Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
DESIGN SPACE EVALUATION OF FORMULATION AND PROCESS VARIABLES OF REPAGLINIDE TRANSDERMAL THERAPEUTIC SYSTEM
Repaglinide, a blood-glucose-lowering drug, has low oral bioavailability (56 %) due to first-pass metabolism and shorter half-life (~1 hour) lead to frequent dosing to control blood glucose level. Repaglinide Transdermal Therapeutic System (TTS) was prepared to provide continuous drug delivery for a prolonged period of time. Factors affecting critical quality attributes (CQA) of Repaglinide TTS ar...
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FABRICATION AND EVALUATION OF ELASTOSOMES OF BOSWELLIA SERRATA FOR TRANSDERMAL DRUG DELIVERY
The extracts of Boswellia serrata possess notable medicinal uses. Boswellia serrata is a highly lipophilic drug. It undergoes extensive hepatic first-pass metabolism. The t1/2 is approximately 6 h. There are reported side effects with the administration of Boswellia serrata. This research work aims to fabricate Elastosomes which get hold of many desired features for transdermal drug delivery. The ...
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IMPACT OF SOCIO-DEMOGRAPHIC FACTORS ON THE BONE IN DIABETIC OSTEOPOROSIS POSTMENOPAUSAL WOMEN
Background: Diabetic postmenopausal women and osteoporosis are both chronic conditions and the relationship between them are complex. Objective: The aims of this study were to assess the socio-demographic factors inflicted in Diabetic postmenopausal women with Osteoporosis condition. Method: A Prospective, comparative and interventional study with a convenient sample of 520 Diabetic postmenopausal...
2096
1173
EVALUATION OF SYNERGIC ANTIDEPRESSANT ACTIVITY OF NARDOSTACHYS JATAMANSI WHEN GIVEN ALONG WITH IMIPRAMINE IN WISTER ALBINO RATS AND SWISS ALBINO MICE
Background: Depression is affecting around 5% of the population. In the traditional systems of medicine, many plants and formulations have been used to treat depression for thousands of years. Objectives: This study evaluated the synergic effect of Hydro-alcoholic extract of Rhizomes of Nordostachys jatamansi DC Per Se with combination with Imipramine in Wistar, albino rats, and swiss albino mice ...
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DNA INTERACTION STUDIES BY UV OF COPPER COMPLEX BASED ON HETEROCYCLIC CHALCONES
Privileged structures have been widely used as an effective template in medicinal chemistry for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring compounds. Chalcones, considered as the precursors of flavonoids and isoflavonoids, are abundant in edible plants. Chalcone metal complexes and their derivatives have been known over the past fifty years. Copper is an...
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SHORT TERM (21 DAYS) TOXIC IMPLICATIONS OF PERMETHRIN ON REPRODUCTIVE TISSUES OF MALE SWISS ALBINO MICE
Permethrin, a member of one of the newest class of insecticides, the synthetic type-I pyrethroids, is very much in use nowadays. Due to its relatively low mammalian toxicity and high photostability, it has earned great popularity. Several reports suggest its endocrine disrupting activity, damaging effect on nervous system, its receptors, and other adverse effects. However, very limited information...
2024
1143
ROLE OF MRP–1 IN THE REGULATION OF STEROID RESPONSIVENESS IN UNCONTROLLED ASTHMA
Introduction: Inhaled Corticosteroids remain the mainstay therapy for asthma. Uncontrolled asthma (UA) dose not respond to the highest inhaled corticosteroids, which remains a challenge for clinicians. Multidrug resistance-associated protein 1 (MRP-1) are molecular "pumps," which expel toxins and modulate corticosteroids' pharmacokinetics and may lead to UA. Moreover, their role in UA is still not...
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EVALUATION OF PROMISING ANTIOBESITY ACTIVITY OF ETHANOLIC EXTRACT OF NIGELLA SATIVA SEED ON HIGH FAT DIET-INDUCED OBESE RATS
Nigella sativa (N. sativa) (Family Ranunculaceae) is a widely used medicinal plant throughout the world. Seeds and oil have a long history of folklore usage in various systems of medicines and food. Extensive studies of literature has been revealed that N. sativa has to carry antidiabetic, anticancer, immunomodulator, analgesic, antimicrobial, anti-inflammatory, spasmolytic, bronchodilator, hepato...
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TO DISCERN AND DERACINATE THE ACTIVE CONGLOMERATE FROM HERBS IN ANTAGONISM TO FOOD POISON EFFECTUATE S. AUREUS – AN IN-VITRO PHYTOTHERAPY
Medicinal plants are widely used to treat disease in non-industrialized societies for not being far cheaper than modern medicines. In this study, five types of medicinal plants viz., Glycyrrhiza glabra, Aegle marmelos, Centella asiatica, Cinnamomum verum, Cynodon dactylon were collected from Alwarkurichi, Tirunelveli District, Tamil Nadu, and extracts were prepared using various solvents such as m...
2093
1123
PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND CARBOHYDRATE DIGESTING ENZYME INHIBITORY POTENTIAL OF LEUCAENA LEUCOCEPHALA LEAVES EXTRACT
The study aims to investigate the antioxidant and antidiabetic activity of Leucaena leucocephala ethanol leaf extract (LLME). L. leucocephala leaves extraction was carried out by the maceration method. Phytochemical analysis was performed using standard analytical procedures. Diphenyl picrylhydrazyl (DPPH) radical and 2, 2’-azinobis (3-ethylbenzathiazoline-6-sulfonic acid) (ABTS) radical scaveng...
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