Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
A CASE CONTROL STUDY OF OXIDATIVE STRESS AND INFLAMMATION IN TUNISIAN PATIENTS WITH ISCHEMIC HEART DISEASE
Ischemic heart disease (IHD) is the major cause of morbid-mortality in most countries. The involvement of inflammation and oxidative stress (OS) in the development of atherosclerosis, ischemic cardiopathy triggering phenomen, has been investigated. The high sensitive C-reactive protein (hs_CRP) was measured in serum by immunoenzymatic method. Serum total homocysteine (Hcy) concentration was measur...
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SYNTHESIS AND CHARACTERIZATION OF BIOLOGICALLY ACTIVE COMPOUND E-2-((2-AMINO PYRIDINE-3-YL) METHYLENE AMINO) ETHANE THIOL AND ITS METAL COMPLEXES
A new physiologically active compound E-2-((2-amino pyridine-3-yl) methylene amino)ethane thiol derived from the condensation of Cysteamine and 2-amino Pyridine 3-Carbaldehyde was synthesized and characterized by spectral techniques like IR, UV-Vis,1H- NMR, TG-DTA, ESR, CHN analyses. The complexes were further screened for their biological activity at Nishka labs and Nickel and Cobalt complexes we...
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CRISPR/Cas9 TECHNOLOGY- A NEW BOON IN GENOME EDITING
Targeted genome engineering provides the ability to precisely modify genetic information in order to study gene function, biological mechanisms, and disease pathology. Historically, random mutagenesis or low-efficiency homologous recombination were used to modify the genomes of cell lines or animal models. However, new advances in the design of sequence-specific endonucleases have enabled more eff...
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ASSESSMENT AND COMPARISON OF EFFICACY OF MIDAZOLAM AND DIAZEPAM AS PREOPERATIVE MEDICATION
Objective: To compare the drugs: Midazolam and diazepam as preoperative medication. Materials and methods: 100 patients aged between 18-60, scheduled for elective surgery were included in this comparative study. Patients were randomly allocated into two groups of 50 each. Materials and methods: Patients received 0.08mg/kg body weight midazolam inject intramuscularly and diazepam 10 mg orally. Asse...
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ISOLATION AND DEVELOPMENT OF AN HPLC METHOD FOR THE QUANTIFICATION OF A BIOMARKER IN THE ROOTS OF PAULLINIA PINNATA
An RP-HPLC method to be used to quantitate the amount of a biomarker in the roots of Paullinia pinnata was developed. The root bark was milled and extracted and the dry powder obtained taken through column chromatography (CC). The biomarker was then isolated. The melting point of the biomarker was determined and found to be 117-119 oC. A RP-HPLC method was successfully developed and used to quanti...
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IMPACT OF AN EDUCATIONAL INTERVENTION ON ASTHMA KNOWLEDGE AND METERED-DOSE INHALER TECHNIQUE AMONG NURSING STUDENTS OF GOVERNMENT COLLEGE OF NURSING, BENGALURU
Nurses being one of the important members of the healthcare team, play a significant role in providing care and education. Current effective treatments for asthma are in the form of metered-dose inhalers. An effective control is achieved only when the patient is comfortable to use the metered-dose inhaler device correctly. This study was therefore planned to evaluate their knowledge and to assess ...
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A STUDY TO EVALUATE USAGE OF ANTIMICROBIAL AGENTS AT PRIMARY HEALTH CENTRES AND URBAN HEALTH CENTRES IN AHMEDABAD DISTRICT
Aims and Objectives: To evaluate the use and the impact of interventions on the use of antimicrobial agents (AMAs) at Primary Health Centres (PHCs) and Urban Health Centres (UHCs) in Ahmedabad district. Materials and methods: This was an interventional and prospective study carried out at 5 PHCs and 5 UHCs of ahmedabad district. In pre-intervention phase, 30 adult patients from each centre who wer...
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STUDY OF THE EFFECT OF MELATONIN ON RETENTION OF CONDITIONED AVOIDANCE RESPONSE AND ON ENHANCEMENT OF SEROTONIN MEDIATED BEHAVIOURAL RESPONSES AFTER ELECTROCONVULSIVE SHOCK (ECS) ADMINISTRATION IN RATS
Objectives: To obtain the data regarding the effects of melatonin on retention of conditioned avoidance response (CAR) and on enhancement of serotonin mediated behavioural responses after electroconvulsive shock (ECS) administration in rats. Methods: Forty rats after training for conditioned avoidance response by using Cook’s pole climbing apparatus were divided in four groups with ten rats in e...
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ANTIBIOTIC DE-ESCALATION IN THE INTENSIVE THERAPY UNIT- A REVIEW
An antibiotic may be defined as a substance or compound that kills or inhibits the growth of, bacteria. Antibiotics belong to the broader group of antimicrobial compounds, used to treat infections caused by microorganisms, including fungi and protozoa, viruses. Antibiotic de-escalation is a mechanism whereby the provision of effective initial antibiotic treatment is achieved while avoiding unneces...
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EFFECT OF INGREDIENTS OF A LOCAL ANTIDIABETIC FORMULATION IN ENHANCING THE ANTIDIABETIC ACTIVITY OF SALACIA RETICULATA IN ALLOXAN INDUCED DIABETIC RATS
Salacia reticulata, used in traditional and local medicines in Western Ghats of Southern India for the treatment of hyperglycaemia, is widely used for its sugar lowering activity. Accordingly, the present study was designed to investigate the possible actions of ethanolic extract of roots of Salacia reticulate (EESR) and an ethanolic extract of local formulation (EELF) made by mixing roots of Sala...
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