Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
EFFECT OF COMPACTION PROCESS IN GRANULOMETRY
Quetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The aim of the present study is to evaluate the effect of manufacturing process on critical quality attribute on In-process parameters (Granules). Quetiapine fumarate was selected as a model drug for sustained release drug delivery system manufactured ...
6459
2132
A NEW SINGLE STABILITY INDICATING RP-ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY (RP-UPLC) METHOD FOR EVALUATION OF ASSAY OF BICALUTAMIDE FROM DOSAGE FORM AND SUITABILITY OF METHOD FOR DETERMINATION OF DISSOLUTION RATE AND RESIDUE ANALYSIS.
A new single stability-indicating isocratic reversed phase ultra-performance liquid chromatographic (RP-UPLC) method with a shortest run time of 2.5 minutes is developed for the determination of assay of bicalutamide an anti-cancer drug from its finished dosage form in the presence of its forced degradation products. The method is developed using Waters Aquity BEH C18 column with mobile phase cont...
4134
1497
SYNTHESIS AND CHARACTERIZATION OF [16]- MEMBERED DIOXA DIAZA NAPTHALDEHYDE BASED MACROCYCLIC LIGAND AND ITS COMPLEXES OF Co(III), Ni(II) AND Cu(II) PERCHLORATE IONS
An hitherto new unreported [16]-membered dioxadiazanapthaldehyde based macrocyclic ligand (L) 2,11-dioxa-23,30-diaza heptacyclo [30.4.0.04,9.012,21.014,19.024,29.034,39] -tetraconta-12,14,16, 18,20,22, 24,26,28,30,32,34,36,38,40-pentadecaene, has been synthesized by two different synthetic routes each involving two stages. 2-Hydroxy-1-Napthaldehyde in the presence of potassium carbonate was trea...
3380
1460
EFFICACY OF SODIUM HYPOCHLORITE IN CONTROLLING BACTERIAL INFECTIONS IN FIFTH INSTAR LARVAE OF ANTHEREAE MYLITTA DRURY (DABA TV)
Bacterial diseases are highly virulent and cause significant crop loss in Anthereae mylittadrury (Daba TV).Therefore an attempt has been made to evaluate the efficient concentration of sodium hypochlorite in controlling bacterial infection through studies on mortality, Total haemocytes, Protein carbonyl content, Alanine transaminase, Aspartate transaminase in the fifth in star larvae. Results reve...
3828
1511
ALTERATIONS IN PLASMA ANTIOXIDANT ENZYME LEVELS AND SERUM LIPID PROFILE PARAMETERS IN RELATION TO LIPID PEROXIDATION IN INDIVIDUALS WITH MATERNALLY INHERITED TYPE 2 DIABETES MELLITUS
Aim: The present study aimed to evaluate the antioxidant potential and lipid profile parameters, in relation to lipid peroxidation in patients with maternally inherited type 2 diabetes mellitus and in healthy normal individuals. Methods: All standard methods were used to estimate enzymatic antioxidants [Catalase, Copper containing Superoxide Dismutase (CuSOD), Manganese containing Superoxide Dismu...
4495
1498
THE EFFECT OF DOXYCYCLINE HYDROCHLORIDE ON MMP-2 AND 9 IN EXPERIMENTALLY INDUCED PERIODONTITIS – AN ANIMAL STUDY
The periodontal tissues undergo constant changes of remodelling when subject to bacterial infection and the resultant host response. The balance between enzymes secreted by the host such as matrix metalloproteinases (MMPs) and their antagonists tissue inhibitor of metalloproteinases (TIMPs) are major contributors to the progression of periodontal destruction. A sub-type of MMPs referred to gelatin...
3738
1531
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTIFICATION OF BETULINIC ACID IN VITEX NEGUNDO L. AND ITS POLYHERBAL FORMULATIONS
The Vitex negundo, which is traditional Indian medicine, has been used for treatment of various diseases. A simple, sensitive, precise and accurate RP-HPLC method has been developed for the analysis of Vitex negundo L. samples and its polyherbal formulations for their Betulinic acid content. The extraction was checked using different solvents like methanol, chloroform, 95% ethanol, acetone and dic...
5180
1684
SATURATION SOLUBILITY OF SCOPOLAMINE IN THIN FILMS OF POLYACRYLATE PRESSURE SENSITIVE ADHESIVES IS TEMPERATURE DEPENDENT
The method of drug uptake from solid solution has been used to measure the saturation solubility of scopolamine base in various pressure sensitive adhesive DURO-TAKs at elevated temperature. The saturation solubility was strongly temperature dependent, being 50 – 100 % larger at 45°C than at 25°C. The higher temperature also caused much more rapid approach to equilibrium distribution of the dr...
4981
1867
SYNTHESIS OF QUINOLINE DERIVATIVES BY REACTION OF DIMETHYL(2R,3S,4R)-2-PHENYL-4-(PHENYLAMINO)-1,3,4-TRIHYDROQUINOLINE-2,3-DICARBOXYLATE WITH SOME AMINES
In this work, quinoline derivatives were synthesized from reaction of aniline, benzylaldehyde and dimethylacetylene dicarboxylate (DMAD) in sequent steps to provide quinoline derivative dimethyl (2R, 3S, 4R)-2-phenyl-4-(phenylamino)-1, 3, 4-trihydroquinoline-2,3-dicarboxylate (12). Compound (12), was reacted with some amines such as hydrazine hydrate, urea, thiourea, ethylenediamine, diaminoprop...
5530
1913
TOXICOLOGICAL CHRACTERIZATION OF BRHANMANJISTHADI KVATHA CURNA (BRH) ON THE BASIS OF TOTAL PROTEIN AND ALBUMIN CONTENT, LIPID PROFILE, LIVER FUNCTION, KIDNEY FUNCTION, SERUM URIC ACID AND ENZYMATIC PROPERTY IN RATS’ PLASMA AFTER CHRONIC ADMINISTRATION
Brhanmanjisthadi Kvatha Curna (BRH) an Ayurvedic preparation, is used as a traditional medicine in filariasis in the northern part of the country. After 45 consecutive days of chronic administration of the BRH preparation in rats its toxicological aspects was studied. In the study the total protein content in the plasma was increased (2.80 %) in BRH treated male rats in comparison to their control...
4195
1415