Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 5.2 | 2.73 | 0.64 |
STRUCTURAL DOCKING STUDIES AND BIOLOGICAL EVALUATION OF SOME NEWLY SYNTHESIZED SCHIFF BASE DERIVED QUINAZOLINONE DERIVATIVES
Present studies describe the synthesis of a series of Schiff base derived quinazolinone derivatives (6-14) with the aim to have better anti inflammatory agents. The prepared compounds were characterized using chemical and spectral (IR, NMR and Mass) studies. Pharmacological evaluation of the newly synthesized derivatives indicated that compounds 8, 11 and 14 exhibit significant anti-inflammatory...
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1530
GREEN SYNTHESIS OF SILVER NANOPARTICLES USING TABERNAEMONTANA DIVARICATA AND IN-VITRO CYTOTOXICITY INVESTIGATION AGAINST HUMAN LUNG ADENOCARCINOMA
The present study aims to synthesize highly stable and dispersed cytotoxic silver nanoparticles (AgNPs) from Tabernaemontana divaricata (T. divaricata) leaves extract, by using noble green approach at room temperature. Phytocomponents were investigated using general methods and found good agreement with reported literature. Green synthesized AgNPs were characterized using UV-Vis, FT-IR, XRD, TGA, ...
5051
1999
EFFECT OF DIAZEPAM AND BICUCULLINE IN BODY WEIGHT REGULATION: POSSIBLE ROLE OF GABA TYPE A RECEPTOR
Arcuate nucleus GABAergic system plays an important role in the energy balance evidenced by various studies. The present study was designed to investigate the involvement of GABA type A receptor in experimental obesity. In the present study effects of chronic administration of diazepam (0.5 and 1mg/kg/day, i.p) and bicuculline (0.6 and 1.25mg/kg/day, i.p) specific GABA type A receptor agonist and ...
4599
1323
SCREENING OF ANTIMICROBIAL PROPERTIES OF PHENOL SCHIFF BASES
In their fight for supremacy and survival, microorganisms have been developing and devising various methods to inactivate the action of antibiotics. The numbers of drug resistant microorganisms with reduced susceptibility to various antibiotics are increasing. Therefore, new infection-fighting strategies are required to control microbial infections. The interaction between potent chemicals and liv...
3624
1275
ASSESSMENT OF POTENTIAL EFFECT OF ANTIEPILPETIC DRUGS ON LIPID PROFILE AND C-REACTIVE PROTEIN AS PREDICTORS OF VASCULAR DISEASE IN EPILEPSY PATIENTS
Epilepsy is a neurological disorder which often requires lifelong treatment with antiepileptic drugs (AEDs). Prolonged use of AEDs is associated with changes in vascular risk markers. Hence, the study was designed to evaluate the effect of older generation AEDs (carbamazepine and phenytoin) and newer generation AED (levetiracetam) monotherapy on the markers of vascular risk in epilepsy patients. T...
3457
1136
BIOCHEMICAL CHARACTERIZATION OF PROTEASE FROM ZINGIBER OFFICINALE RHIZOME BY USING NEURAL NETWORKING APPROACH
Biochemical characterization of enzyme is the most fundamental aspects of enzymology from industrial point, as it is desirable to choose an enzyme which will have the fastest reaction rate per unit amount of enzyme which indicates the maximum effect for the minimum amount of added catalyst. In this study, Protease enzyme was extracted from Z. officinale and purified by using various down streaming...
3149
1192
BIOPHYTUM SENSITIVUM DC.: A REVIEW
Biophytum sensitivum DC. (Family - Oxalidaceae), commonly known as “Lajjalu” in Northern India, is an annual herb that grows at the foothills of the Himalayas. It is an indigenous medicine, used against “Madhumeha” (Diabetes mellitus) apart from being used as tonic, stimulant, and in the treatment of stomach ache, asthma, insomnia, convulsions, cramps, chest-complaints, inflammations, tumo...
11530
2714
PHYSICOCHEMICAL, ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF A MULTIPURPOSE HERBAL FORMULATION (HB-01)
An herbal formulation composed of Allium cepa (Onion), Zingiber officinale (Ginger), Allium sativum (Garlic), Aloe vera, Andrographis paniculata (King of bitters), Allium ascalonicum (Shallot), reportedly used as anti–inflammatory agent was investigated. This study evaluated the physicochemical, phytochemical properties and in vivo anti–inflammatory effect of the herbal formulation. The herbal...
3392
1713
PHENOTYPICALLY AND GENETICALLY VARIATION OF Rif r MUTANTS STRAINS OF PSEUDOMONAS FLUORESCENCE pf2T2 AND pf2m1
The present study was Rifampicin-resistant (Rif r) mutants of Pseudomonas fluorescens pf2T2 and pf2m1 were isolated from different localities of onion plant rhizosphere soil in an around the Tamil Nadu. However, the mutants of P. fluorescens were of two general categories. Group 1 showed fast growing in terms of growth rate, competitive fitness, and membrane protein composition. Group 2 showed a s...
2859
1121
ANALGESIC, ANTIINFLAMMATORY AND ANTIPYRETIC ACTIVITY OF TRICHOSANTHES DIOICA ROXB. LEAF EXTRACTS
Aim of the study: This study evaluates the analgesic, anti-inflammatory and antipyretic activities of the aqueous, methanol and n-hexane extracts of Trichosanthes dioica Roxb. to provide experimental evidence for its traditional use such as fever, pain and inflammation. Materials and methods: Investigations on the analgesic effects of Trichosanthes dioica Roxb. was carried out by acetic acid-induc...
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