Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SEASONAL FLUCTUATIONS IN ARBUSCULAR MYCORRHIZAL FUNGAL COMMUNITIES: A REVIEW
Arbuscular mycorrhizal fungi (AMF) enjoy being the cynosure in most agro-ecosystems. These fungi benefit the plant in multiple ways. They improve plant growth by enhancing nutrient uptake and protecting the plant from various plant pathogens, thereby promoting plant diversity. These fungi improve plant tolerance to various abiotic stresses, such as salinity, drought, extreme temperatures, and heav...
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QUALITATIVE AND QUANTITATIVE ESTIMATION OF TYROSINE KINASE INHIBITORS IN PHARMACEUTICAL AND BIOLOGICAL MATRICES – AN OVERVIEW
Tyrosine kinase inhibitors generally having a narrow therapeutic window and large inter-patient variability. In order to support its therapeutic drug monitoring, fast and accurate methods are needed to supporting the pharmacokinetic-guided dosing in patients treating with various tyrosine kinase inhibitors (TKIs) either alone or in combination in bulk, formulations or human plasma using HPLC and d...
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A REVIEW ON HEALTH ISSUES AND PLAUSIBLE REMEDIES IN MENTALLY CHALLENGED CHILDREN
The bioavailability of conventional ophthalmic solutions is very poor due to efficient protective mechanisms of the eye, blinking, reflex Mental health problems are characterized by in definite persistently depressed mood, low self-esteem, loss of interest in normal life activities. A common problems were the chances to occurs from generation to generation, i.e., genetic in nature, and these may a...
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QUINAZOLINE HETEROCYCLE AND ITS ANTI-CANCER ACTIVITY: AN OVERVIEW
The aim of this review is to provide an extensive overview of the diverse pharmacological activities of quinazoline moiety. Quinazolines are well-known and important nitrogen-containing heterocyclic compounds made chemical formula C8H6N2. For the last few years, the heterocyclic fused nucleus quinazoline has drawn immense attention due to its diversified application in medicinal chemistry research...
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RATIONAL APPROACHES FOR SYNTHESIS OF SOME NOVEL IMIDAZOLE HETEROCYCLES WITH THEIR BROAD SPECTRUM OF PHARMACOLOGICAL ACTIVITIES: A BRIEF REVIEW
Imidazole has a special role in heterocyclic chemistry, and its derivatives have piqued interest in recent years due to its diverse chemistry and pharmacology properties. Imidazole is a nitrogen-containing heterocyclic ring that is essential in biology and pharmaceuticals. As a result, imidazole compounds have piqued the attention of researchers for more than a decade. Thus imidazole compounds hav...
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BIOLOGICS AND BIOSIMILARS- A MEDICINE FROM THE LIFE AND FOR THE LIFE: THE COMPLETE REVIEW
In this review, we are completely discussing different eras in pharmaceutical drugs/medicines, i.e., Biologics and biosimilars. These biologics can be called life drugs because they are deriving from living organisms, microbes, yeast, bacteria, and human blood products. These biologics are biopharmaceutical products that are derived from living organisms and are very complex in molecular structure...
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PREDICTION OF HOTSPOT IN PROTEIN-PROTEIN/PROTEIN-SUBSTRATE INTERACTION: A NOVEL COMPUTATIONAL APPROACH
Protein-protein, as well as protein-substrate interactions, play an important role in regulating specific biological functions like signal transduction, apoptosis, gene regulation, and immune response. These play a major role in drug discovery applications and can be used as molecular targets to stop disease development at the molecular level. Thus, understanding the biological mechanism of protei...
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HPLC METHOD FOR ESTIMATION OF VALTRATE IN VALERIANA JATAMANSI AND VALERIANA PYROLAEFOLIA
Valtrate is one of the major valepotriates reported from various species of the genus Valeriana. Aim of the present study was to develop and validate analytical method for quantification of valtrate in dried roots of Valeriana jatamansi and Valeriana pyrolaefolia, both members of family Valerianaceae. Acetonitrile and water (70:30) in isocratic mode were used with an aflow rate of 1.5 mL/min (at 2...
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STABILITY INDICATING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR SIMULTANEOUS ESTIMATION OF ACEBROPHYLLINE AND DOXOFYLLINE IN PHARMACEUTICAL DOSAGE FORM
Objective: To develop a simple, selective, and precise stability-indicating high-performance liquid chromatography method for the simultaneous estimation of acebrophylline and doxofylline in bulk and tablet dosage form. Methods: The chromatographic separation achieved on HiQSil C18 Column (250 × 4.6 mm, 5µm) utilizing a mobile phase Acetonitrile: 10 mM n-hexane sulfonic acid buffer (80: 20, v/v)...
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DEVELOPMENT AND EVALUATION OF POMALIDOMIDE SUPERSATURABLE SELF-NANOEMULSIFYING DRUG DELIVERY SYSTEM FOR IMPROVED SOLUBILITY AND DISSOLUTION RATE
Background: Pomalidomide belongs to BCS class IV drug with low solubility and undergoes first-pass metabolism leads to reduced bioavailability of 15%. Objective: The current study aimed to develop pomalidomide Super saturable-SNEDDS to enhance solubility. Methods: Preliminary solubility studies were performed to identify oil, surfactant, and co-surfactant ratios. Pseudo tertiary phase diagram cons...
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