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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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Most Cited

CITATIONS REPORT: (Source- Google Scholar)
 
Year 202020212022Total
No. of Published Articles 745760548 2053
Citations 69926321 983
Projected Impact Factor 5.22.730.64  
Total Citations: 58203
 
Title
Views
PDF
Cited
21.

MOLECULAR DOCKING, PHARMACOPHORE MODELLING AND 3D QSAR ANALYSIS OF NOVEL CHALCONE DERIVATIVES

Chalcone based structures have many interesting biological properties like anti-malarial, anticancer, antiviral, antibacterial, antifungal, anti-hyperglycaemic and photo-cytotoxicity activities. In this study, the novel chalcone derivatives (1a-1l) have been synthesized and investigated for antimicrobial activities. The MIC results of antimicrobial activities reveal that one of the chalcone deriva...

S. A. Gandhi *, V. M. Barot, M. C. Patel, T. J. Malek and U. H. Patel

Bhavan’s Shri I. L. Pandya Arts, Science and Smt. J. M. Shah Commerce College, Dakor, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1725-33

1725-1733

2945

1365

22.

METHYLATION EFFECT OF APIGENIN 8-C-GLUCOSIDE TOWARDS ANTIOXIDANT POTENTIAL – A DFT STUDY

The extensive study on O - methylated flavonoids reveals that substitution with methyl group enhances the radical scavenging behavior in certain compounds. Due to potential applications of C-glycosides in metabolic engineering, methylation in these flavonoids needs to be analyzed in both theoretical and experimental levels for their radical scavenging behavior. In this work naturally occurring C- ...

K. Anbazhakan, R. Praveena * and K. Sadasivam

Department of Chemistry, Bannari Amman Institute of Technology, Sathyamangalam, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1734-40

1734-1740

2543

1072

23.

ANTIOBESITY, ANTIHYPERLIPIDEMIC AND ANTIDIABETIC AGENTS OF PROTO-CATECHUIC ACID IN HIGH FATTY DIET ALONG WITH ALLOXAN INDUCED DIABETES

Aim: The present investigation was carried out by evaluating the effect of protocatechuic acid (PCA) on a high-fat diet (HFD) along with a low dose of alloxan-induced hyperglycemia in male Wistar rats. Methods: In the present study, administration of high fatty diet (HFD) for 45 days  along with low dose of alloxan (80 mg/kg) in rats on 30 days produced significant high fatty diet in the, body we...

M. Rajguru *, S. Tembhurne and S. Kolhe

Department of Pharmacology, AISSMS College of Pharmacy, Savitribai Phule Pune University, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1741-46

1741-1746

2537

1026

27.

FORMULATION DEVELOPMENT AND IN-VITRO CHARACTERIZATION OF FAST DISSOLVING POLYMERIC FILMS OF OLANZAPINE FOR THE MANAGEMENT OF PANIC ATTACK OF SCHIZOPHRENIA

Schizophrenia is a severe and disabling disorder which needs immediate administration of a suitable drug. Olanzapine, a BCS class II atypical antipsychotics drug of thienobenzodiazepine class is frequently prescribed to treat schizophrenia. The aim of the present investigation was to formulate mouth dissolving films of Olanzapine to improve its solubility and patient compliance. An inclusion compl...

M. Momin *, S. Lalka, S. Mhatre and S. Mistry

Department of Pharmaceutics, SVKM’s Dr. Bhanuben Nanavati College of Pharmacy, Mithibai Campus, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1765-74

1765-1774

3212

1217

28.

SHORT-TERM TREATMENT OF ELASTASE-LPS INDUCED EXACERBATION MODEL OF EMPHYSEMA IN MICE WITH DOCOSAHEXAENOIC ACID, A PRECURSOR OF ANTI-INFLAMMATORY AUTACOIDS

An essential pathological phenotype of chronic obstructive pulmonary disease is emphysema or lung tissue destruction. The study aims to assess docosahexaenoic acid (DHA), a precursor for specialized pro-resolving mediators, as a treatment of emphysema. Albino mice were challenged with porcine pancreatic elastase on day 1 and bacterial lipopolysaccharide on day 21 to induce emphysema. The pathologi...

S. Sarkar

Department of Pathology and Cancer Screening, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1775-83

1775-1783

2506

952

29.

IN-VIVO PHARMACOKINETIC EVALUATION OF PIOGLITAZONE – HPMC K 15 M FLOATING TABLETS

The objective of the study is to make a pharmacokinetic evaluation of Pioglitazone floating tablets formulated employing HPMC K 15 M in comparison to Pioglitazone pure drug in rabbits. The two products were tested in a crossover RBD in healthy rabbits of either sex (n=6). The plasma concentrations of Pioglitazone were determined by a validated HPLC method. From the time versus plasma concentration...

G. C. Devi

University College of Pharmaceutical Sciences, Palamuru University, Bandameedipally, Mahabub Nagar, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1784-86

1784-1786

2143

897

30.

OXIDATIVE DETERMINATION OF SOME ANTIHISTAMINE DRUGS IN PURE FORM AND THEIR PHARMACEUTICAL PREPARATIONS BY USING PYRIDINIUM FLUORO CHROMATE (PFC) REAGENT

In this paper Chromium (VI) based Pyridinium fluoro chromate (PFC) reagent has been used as an oxidant for the determination of some antihistamine drugs e.g. Promethazine hydrochloride (PMH) and Pheniramine maleate (PM) in pure form and their pharmaceutical preparations such as Phenergan (Injection and tablet) and Avil (Tablet and injection) respectively. The main principle of this method is based...

A. K. Pandey * and D. Dwivedi

Department of Chemistry, Pt. S.N.S. Govt P.G. (Auto) College, Shahdol, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1787-94

1787-1794

2618

1443

31.

EFFECTS OF ANETHUM GRAVEOLENSE LINN. EXTRACT ON BILE DUCT LIGATION INDUCED HEPATIC FIBROSIS IN RATS

The present study investigated the protective role of methanolic extract from Anethum graveolense L. (AGME) on bile duct ligation (BDL) produce hepatic fibrosis in the rat. BDL rats were divided into four groups, which received orally distilled water or AGME (200 and 400 mg/kg) for continuously 28 days. The BDL induced hepatic fibrosis by anti-fibrotic effect of AGME in the rats determined by seru...

S. Ali *, A. Maiti and V. K. Vishwakarma

Department of Pharmacology, Rajarshi Rananjay Singh College of Pharmacy, Amethi, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1795-03

1795-1803

2448

1112

32.

DESIGN AND OPTIMIZATION OF CAPECITABINE NIOSOMES DERIVED FROM PRONIOSOMES

The aim of this investigation was to design and optimize the Capecitabine niosomes derived from proniosomes using central composite design. Two independent variables viz., the molar ratio of drug to cholesterol (X1), surfactant loading (X2) and two dependent variables viz., the percentage drug entrapment (PDE) and mean volume diameter (MVD) were selected for the study. Proniosomes were prepared by...

Srikanth *, Y. A. Kumar and C. M. Setty

Jawaharlal Nehru Technological University (JNTU), Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1804-10

1804-1810

2584

1098

33.

SIMULTANEOUS ESTIMATION AND ANALYTICAL METHOD DEVELOPMENT, VALIDATION FOR THE TENELIGLIPTIN AND METFORMIN BY RP-UFLC

The study aims to develop an analytical method for the simultaneous estimation of Teneligliptin and Metformin using RP-UFLC. A simple, sensitive and accurate method was developed for Teneligliptin and Metformin using the chromatographic conditions of C18 Phenomenex Kinetex (250 mm × 4.6 mm i.e., 5 μm particle size) column in gradient elution mode with the mobile phase consisting of methanol, ace...

R. Maruthi *, R. S. Chandan and P. Raikar

Department of Pharmaceutical Chemistry, JSS College of Pharmacy, JSS Academy of Higher Education and Research, Mysuru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1811-19

1811-1819

3304

1271