Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 5.2 | 2.73 | 0.64 |
BIOMATERIAL BASED INJECTABLE HYDROGEL FOR CONTROLLED DRUG DELIVERY: A REVIEW
The aim of a pharmaceutical product is to obtain excellent therapeutic and favorable treatment. Controlled drug release coatings have been around for more than 50 years and their performance has increased significantly since the beginning. The main drawbacks of the controlled drug delivery system are its poor bioavailability, high-dose requirements, adverse side effects, low therapeutic indices,...
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1848
ENHANCEMENT OF POOR ORAL ABSORPTION DRUG VIA LIPID FORMULATION: SELF EMULSIFYING DRUG DELIVERY SYSTEM
The oral route of drug administration is one of the simplest route of drug administration throughout the world because its patients convenience. The drug administered through orally should possess good aqueous solubility for better oral absorption and thus bioavailability will increase. But it was found that 30-40% of the drug shows low solubility thus bioavailability profile will be affected. Sel...
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A REVIEW ON OBESITY COMPLICATIONS AND ITS MANAGEMENT
The article focuses on the prevalence of obesity in India, increasing levels of childhood obesity, and the potential health hazards that result from obesity, thereby suggesting the necessary preventive measures and the prevailing natural and synthetic therapy that can help to cure the disease, thus spreading awareness about its severity and necessity for treatment. Obesity in India has reached epi...
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A REVIEW ON CHROMEN DERIVATIVES AS ANTIEPILEPTICS
Chromens are oxygen-containing heterocycles, abundantly found in nature in the form of flavone, is flavones, flavanones, catechins, anthocyanins and collectively known as flavonoids and isoflavonoids. Being a polar and ionizable aromatic compound, it improves the pharmacokinetic characteristics of lead molecules. Imidazole derivatives have occupied a unique place in the field of medicinal chemistr...
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1022
FABRICATION AND COMPARATIVE EVALUATION OF CURCUMIN AND PACLITAXEL- LOADED SOLID LIPID NANOPARTICLE; THE PATHWAY OF EFFECTIVE CANCER THERAPY
The objective of the present study is to develop, evaluate and compare potent phytoconstituents of curcumin loaded solid lipid nanoparticles (CUR-SLN) and Paclitaxel loaded solid lipid nanoparticles (PTX-SLN) for the treatment of malignancy. Curcumin is an active phenolic compound of Curcuma longa as a promising phytoconstituent has been extensively studied over the past several years. The result ...
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STEADY SHEAR AND DYNAMIC SHEAR RHEOLOGICAL PROPERTIES OF CARBOXY-METHYL LOCUST BEAN GUM INFLUENCING EROSION OF THE POLYSACCHARIDE COAT OF COMPRESSION COATED TABLETS
Rheological properties of carboxymethyl locust bean gum (CMLBG) solutions having different concentrations and solution pH were evaluated through steady shear and oscillatory measurements and were used to describe the erosion propensity of CMLBG coat of compression coated placebo tablets. CMLBG solutions, irrespective of concentration and solution pH, exhibited predominant viscous character as the ...
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ANTIBACTERIAL ACTIVITY OF ANDROGRAPHIS PANICULATA OF METHANOLIC EXTRACT AGAINST SOME HUMAN PATHOGENIC BACTERIA AND EFFECT OF ANDROGRAPHOLIDE COMPOUND AGAINST BACTERIAL PATHOGEN
Cold and hot methanolic extract of leaves and whole plant parts of Andrographis paniculata were tested against gram-negative Escherichia coli (MTCC 1679) Klebsiella pneumonia (MTCC 4032) Streptococcus pyogenes, Solmonella typhimurium (MTCC733) and gram-positive Staphylococcus aureus (MTCC737). Maximum activity among all the bacterial cultures tested was showed against E. coli MTCC1679 when compare...
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ANTHROPOMETRIC AND BIOCHEMICAL ANALYSIS OF NORMAL AND OBESE SUBJECTS ON AN INDIAN POPULATION
Obesity is a very serious health problem worldwide. Obesity depends on several physical and bio-chemicals parameters that are discussed in this work, i.e., BMI, cholesterol level that includes Total cholesterol (TC), High density lipoprotein concentration (HDL-c), Low density lipoprotein (LDL-c), Triglycerides level (TG), Glucose level, Postprandial glucose level. The present study throws light on...
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EXERCISE-INDUCED OXIDATIVE STRESS MANAGEMENT BY METHANOLIC EXTRACT OF ZINGIBER OFFICINALIS ON SOME VITAL TISSUES IN MALE RAT
Background: Zingiber officinalis known as ginger, under the family Zingiberaceae, is a popular food spice and occupies an important place in Ayurvedic and traditional medicine. Its rhizome is used as antioxidative, carminative and for chronic diseases. Aims: Study indicated the curative effects of methanolic extract of ginger on severe exercise-induced oxidative damage in vital organs. Materials a...
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FORMULATION AND EVALUATION OF COLON TARGETED MICROSPHERES OF GLIPIZIDE
The objective of the present study was to formulate and evaluate microspheres of Glipizide using guar gum and HPMC K4M as polymers for colon-specific delivery for better treatment of Type 2 diabetes. The glipizide microspheres were prepared by ionotropic gelation method by the use of various cross-linking agents. The microspheres were then studied for physical appearance, particle size, surface mo...
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