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PHYTOCHEMICAL AND PHARMACOGNOSTICAL SCREENING OF JASMINUM MULTIFLORUM (BURM. F.) AND JASMINUM MESNYI (HANCE) STEMS
Jasminum multiflorum and Jasminum mesnyi, the ornamental shrubs belonging to family Oleaceae are widely distributed throughout India. Despite their use in the essence industry for making perfumes, oils, and creams, these species are also used in the healing wounds and ulcers, constipation, flatulence, skin diseases, rheumatism, stomatitis, diabetes, stress, antiseptic, diuretics, and gastric distu...
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STABILITY INDICATING ANALYTICAL METHOD VALIDATION FOR SIMULTANEOUS ESTIMATION OF FENTICONAZOLE NITRATE, TINIDAZOLE AND LIDOCAINE BY REVERSED PHASE-HPLC
The current study aims to develop a reversed-phase HPLC method for quantifying the active substances of Fenticonazole Nitrate (FENTI), Tinidazole (TINI) and Lidocaine base (LIDO) simultaneously and to validate the proposed method for the intended analytical application in the bulk and pharmaceutical dosage form by ICH guidelines. In this work, the behaviour of f FENTI, TINI and LIDO was studied un...
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QBD APPROACH TO DEVELOP RP-HPLC METHOD FOR CAPECITABINE IN BULK AND DOSAGE FORM
A simple, specific, accurate, reliable, and precise reverse-phase high-performance liquid chromatographic method was developed by quality by design approach and validated for the estimation of Capecitabine in bulk and tablet dosage forms. A surface methodology was used to optimize the data with a three-level Box Behnken Design (BBD) was used. Mobile phase composition, flow rate, and column oven te...
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STRENGTHENING IMMUNIZATION SYSTEMS THROUGH EFFECTIVE SUPPLY CHAINS: INSIGHTS FROM GLOBAL EFFECTIVE VACCINE MANAGEMENT INITIATIVE
The Expanded Programme on Immunization (EPI), launched in 1974, is the world’s major vaccination program against vaccine preventable diseases. Despite progress, the program’s success, measured through coverage rates, has recently stalled, especially in low-income countries where access to vaccines remains challenging. EPI’s effectiveness relies heavily on the Immunization Supply Chain, but t...
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GENERALIZED ARTIFICIAL NEURAL NETWORK MODELLING AND ITS APPLICATION IN PERFORMANCE PREDICTION OF SUSTAINED RELEASE MONOLITHIC TABLETS
Artificial Intelligence is the simulation of human intelligence. From delivering simple groceries to doorsteps to solving the toughest task in scientists’ lab, it is surrounding human life in all the means. So how can the Pharma industry be untouched in the case of AI?! Artificial Neural Network (ANN) is a type of AI used to solve non-linear problems and predict the output for given input parame...
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ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF NEW TRANSITION METAL COMPLEXES DERIVED FROM 5-(2-(4-METHOXYPHENYL)-1H-BENZO [D] IMIDAZOL-1-YL) QUINOLIN-8-OL
New pharmacologically active transition metal complexes of Co(II), Ni (II), Cu (II), and Zn(II) have been synthesized with the ligand 5-(2-(4-methoxyphenyl)-1H-benzo [d] imidazol-1-yl) quinolin-8-ol (2). Different analytical and spectroscopic tools were used to analyze the compounds, including elemental analysis, FTIR, 1H-NMR, mass spectra, electronic spectra, magnetic measurement, and molar condu...
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PHARMACOGNOSTICAL STANDARDIZATION AND PRELIMINARY PHYTOCHEMICAL INVESTIGATIONS ON ANANAS COMOSUS (L.) MERR.
Pineapple or 'Ananas,' is a tropical fruit that belongs to the Bromeliaceae family. The stem and fruit of this plant are utilized in conventional and folk medicine for treating various illnesses. In addition to calcium, iron, potassium, pineapples are a rich source of vitamin C, B and A. This study involves determinations various standardization specifications for the plant Ananas comosus (L.) Me...
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PHARMACEUTICAL POTENTIAL OF FLEXIRUBIN PIGMENT FROM CHRYSEOBACTERIUM
The study was carried out to isolate and characterize pigment producing bacteria from rhizosphere soil. In our study, isolation and characterization of bacteria that produced pigments were performed using serial dilution, spread plating method followed by gram staining and various other biochemical tests (Oxidase, Catalase and IMViC tests). Our study concluded that bacteria isolated from rhizosphe...
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TAU-PET IMAGING OF BRAIN DAMAGE IN HEAD INJURY
Positron emission tomography (PET) imaging has been broadly used in the study of brain damage for a long time. However, PET has been mostly used for the assessment and detection of neural activity after brain damage. Tau proteins play a significant role in a variety of degenerative neurological conditions. Post-mortem neuropathology studies of victims of repeated and severe head trauma have define...
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MEDICINAL VALUE OF MILLETS FOR HEALTHY LIFE
Millets are one of the oldest foods known to humans and possibly the first cereal grain to be used for domestic purposes. The Indian flatbread roti is made from ground millet seeds. In malice of all these extraordinary rates and capacities of millet husbandry systems, the area under millet products has been shrinking over the last five decades and swiftly after the green revolution period. The bit...
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