Most Popular
ESTIMATE THE SEROPREVALENCE OF TTI IN BLOOD DONORS AND COLLATE THE RISK OF TTI BETWEEN VOLUNTARY DONORS AND REPLACEMENT DONORS
Introduction: The goal of BTS (Blood Transfusion Service) is to provide safe and quality blood and blood products to needy patients. In developing and underdeveloped countries, there exists a gap between the demands and supply of blood products. Since 100% voluntary blood donation is not achieved, we rely on replacement donors also. Hence this study was attempted to assess the seroprevalence of TT...
1668
859
IN-SILICO MOLECULAR DOCKING INSIGHTS OF BIO ACTIVE COMPOUNDS OF GENUS MOMORDICA AND NOVEL SYNTHETIC ANTI –PARKINSON’S DRUG: A PROMISING LEAD IN THE QUEST FOR MAO-B INHIBITORS
Discovering Novel MAO-B inhibitors is promising therapeutic strategy for Parkinson’s disease. The pharmacological effects of MAO-B inhibitor showed significant neuro-protection and improved motor function and reduced oxidative stress marker. In-silico molecular docking simulation to investigate the interaction between target protein (MAO-B Inhibitors) and revealing promising hits with high bindi...
1668
723
HEAVY METAL CONTENTS AND ASSOCIATED HEALTH RISK OF SOME GHANAIAN AND ASIAN HERBAL DRUGS
This study looked at heavy metal levels in selected registered herbal drugs of Asian and unregistered Ghanaian herbal drugs sold in Kumasi. It examined the health risks of the metals. It provided authorities with data to ensure that herbal drugs are strictly monitored and their metal levels evaluated to safeguard patrons' health. Dry ashing method was used on 10g of each of the herbal drug samples...
1667
769
DEVELOPMENT AND OPTIMIZATION OF TRANSDERMAL MICROEMUSION FORMULATION OF BCS CLASS II ANTIDIABETIC DRUG BY DOE
The main aim of present investigation was to examine the potential of a microemulsion formulation developed through simplex lattice design as well as desirability function approach for transdermal delivery of BCS class II anti diabetic drug Glibenclamide. Pseudo-ternary phase diagrams were plotted by water titration method for multiple microemulsion formulations using oleic acid (oil), tween 80 ...
1666
996
THERAPEUTIC EFFECT OF LEAVES OF AYAPANA TRIPLINERVIS IN INDOMETHACIN INDUCED MILD, MODERATE AND SEVERE GRADE GASTRIC ULCER
Peptic ulcer disease (PUD) is increasing gradually in India as well as worldwide. Excess use of non-steroidal anti-inflammatory agents (NSAID) and lifestyle factors cause gastric mucosal damage. This study was designed to search out the gastro-protective efficacy of hydromethanolic extract of Ayapana triplinervis on different graded ulcers. Mild to severe grade of gastric ulcer has been developed ...
1666
1032
SCREENING FOR BIOFILM-FORMING EFFICACY OF CLINICAL ISOLATES
Seven pathogenic isolates with clinical history were procured from the Department of Microbiology, RMMCH, Annamalai University, Chidambaram, Tamil Nadu. Among them, five isolates (S1-S5) showed multi-drug resistance to the selected antibiotics. Maximum multi-drug resistance was exhibited by four Gram negative isolates (S1, S2, S4 and S5). Initial qualitative analysis of these four isolates for bio...
1665
786
IDENTIFICATION AND QUANTIFICATION OF POTENTIAL BIOACTIVE COMPOUNDS FROM SEAWEED OF CHAMPIA COMPRESSA
The present investigation was carried out to analyze the bioactive metabolites of red seaweed Champia compressa collected from Mandapam, Ramanathapuram district, Tamil Nadu, India. The collected sample was evaluated for qualitative and quantitative phytochemical screening analysis using five different solvents methods. The preliminary qualitative analysis of Champia compressa solvent extracts reve...
1665
1038
DUNDEE READY EDUCATION ENVIRONMENT MEASURE (DREEM) TOOL: PERCEPTION OF LEARNING ENVIRONMENT IN A MEDICAL COLLEGE OF INDIA
Background: In the present era of quality accreditation, considering the quality of medical education is also very important, especially in developing countries. The present study was planned to understand the current state of medical education and explore medical students’ perception of their learning environment so that problem areas can be identified both at the institutional and curriculum l...
1665
1311
IN-SILICO ANALYSIS OF GALLIC ACID DERIVATIVES FOR IDENTIFICATION OF NOVEL ALANINE RACEMASE INHIBITORS
Background: In drug design development, Alanine racemase grabbed researchers' attention as it is a potential target for many antimicrobial agents due to its imperative role in bacterial cell wall synthesis. The irresponsible binge eating of antibiotics leads to drug resistance is a key issue of concern for the researchers. The development of multidrug resistance, responsible for causing immense hu...
1664
935
HPTLC METHOD DEVELOPMENT AND VALIDATION FOR HYDROXYCHAVICOL ISOLATED FROM PIPER BETEL LEAVES
A simple, precise, accurate, and rapid high performance thin layer chromatographic method has been developed and completely validated for the estimation of hydroxychavicol isolated from piper betel leaves powder. The isolation of hydroxychavicol was carried out using flash chromatography. Validation was carried out with pre-coated silica gel aluminum plate G 60 F254 (10 x 10 cm) as the stationary ...
1664
1280