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URINARY DYNAMICS IN CHRONIC KIDNEY DISEASES
This review explores the intricate physiology of urine formation and its critical relationship with chronic kidney disease (CKD). Urine formation involves three key processes: glomerular filtration, tubular reabsorption, and tubular secretion, which work together to maintain homeostasis by regulating fluid balance and waste elimination. In CKD, these functions are impaired due to progressive damag...
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AN UPDATE ABOUT MEDICINAL PLANTS USAGE FOR THE TREATMENT OF DIABETES AND SOME OTHER DISEASE IN BUNDELKHAND REGION
Nowadays, some medicinal plants have been reported to be useful in diabetes worldwide and have been used analytically as antidiabetic medicaments. Bundelkhand is a historic zone of central India. This region is known as the land of fighters, sacrifice, and love. It's spread in the range of Uttar Pradesh and Madhya Pradesh state. It includes seven sections of Uttar Pradesh and six sections of Madhy...
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A STUDY ON TERNARY MIXTURE OF PEPTIDE USING ULTRASONIC, IN-VITRO AND IN-SILICO PROCESSES
Penetrating biomolecules by ultrasonic techniques is an innovative and influential tool for characterizing their physicochemical properties. Peptides have been used as extensive applications in drug construction and as an ingredient in nutritional complements. An investigation based on the behavior of the promulgation of ultrasonic waves in solids and the liquid system is now rather well recognize...
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DEVELOPMENT AND OPTIMIZATION OF TRANSDERMAL MICROEMUSION FORMULATION OF BCS CLASS II ANTIDIABETIC DRUG BY DOE
The main aim of present investigation was to examine the potential of a microemulsion formulation developed through simplex lattice design as well as desirability function approach for transdermal delivery of BCS class II anti diabetic drug Glibenclamide. Pseudo-ternary phase diagrams were plotted by water titration method for multiple microemulsion formulations using oleic acid (oil), tween 80 ...
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NOVEL ISOCRATIC RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF OFLOXACIN AND BECLOMETHASONE DIPROPIONATE
The present paper describes a novel, isocratic, simple, precise, accurate, and robust reversed-phase high-performance liquid chromatographic (RP-HPLC) method development and validation for simultaneous quantitative estimation of Ofloxacin and Beclomethasone dipropionate in an Ophthalmic/Otic formulation. The proposed chromatographic estimation was carried out isocratically using Protonsil C18 (250...
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HEPATOPROTECTIVE ACTIVITY OF EXTRACTED FLAVONOIDS FROM ORTHOSIPHON STAMINEUS AGAINST HALOTHANE INDUCED HEPATOTOXICITY IN RATS
Usually, medicine includes the use of herbal medicines, animal parts, and minerals. However, herbal medicines are the most widely used of the three. The general guidelines for policies on Research and Evaluation of Traditional Medicine cover a wide range of issues and are intended to meet the different states in various countries and regions of the world. Orthosiphon stamineus is an herb that is w...
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OPTIMIZATION AND DEVELOPMENT OF TOPICAL METAL ION – CONTAINING ANTIBACTERIAL CREAM AND GELS
Normally and often skin infections present therapeutic challenges to practitioners and researchers due to the growing concern regarding multi-drug resistant bacterial, Viral, and Fungi Strains. The Antibacterial properties of zinc sulphate and copper sulfate are well known and have been investigated for many previous years. However, the synergistic effect between both metal ions as antibacterial i...
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A COMPARATIVE ANALYSIS OF GLASGOW COMA SCALE SCORE WITH FULL OUTLINE OF UNRESPONSIVENESS SCORE IN ASSESSMENT OF PATIENTS WITH TRAUMATIC HEAD INJURY IN INTENSIVE CARE UNIT: A TERTIARY CARE CENTRE STUDY
Background: Neurological assessment of traumatic brain injury patients is of prime importance as it affects the therapeutic and prognostic decisions. GCS (Glasgow Coma Scale), a well recognised and often used scoring system in such cases has some drawbacks. We compared FOUR score (Full Outline of Unresponsiveness) with GCS with an objective to test its validity as an alternative to assess the seve...
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LRTI-SYSTEMATIC APPROACHES TO DIAGNOSIS AND EFFECTIVE THERAPEUTIC MANAGEMENT
Introduction: Lower Respiratory Tract pulls in air from the upper respiratory tract, absorbs oxygen and release carbon dioxide in exchange, infection to this is known as LRTI. It includes Bronchitis, Bronchiolitis, Influenza, Pneumonia, COPD and Asthma. Patients were treated with many medications like Bronchodilators, antibiotics and antivirals. Objectives: To evaluate treatment assessment of resp...
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ISOLATION OF ANTIBACTERIAL PEPTIDE FROM VIGNA ACONITIFOLIA L.
Vigna aconitifolia L. represents a genus in the Fabaceae family and is one of the most drought-resistant legumes, commonly grown in arid and semi-arid regions of India. Therapeutic effects of Vigna aconitifolia L. have been reported in several publications, but there are only a few reports on the biological activities of the Vigna aconitifolia L. proteins. In the present study, antibacterial a...
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