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GC-MS ANALYSIS OF CURCUMA ZEDOARIA TUBER EXTRACTS AND ITS ANTIBACTERIAL ACTIVITY
This study investigates the presence of bioactive compounds present in the tubers of Curcuma zedoaria using GC-MS analysis. Different compounds, including alkaloids, tannins, flavonoids, and proteins, were identified using the preliminary phytochemical screening for aqueous, ethanol and methanol extracts. The present study reports the antimicrobial activity analysis using aqueous, ethanol and meth...
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TRADITIONAL MEDICINAL PLANTS USED FOR THE TREATMENT OF RESPIRATORY PROBLEMS IN INDIA: A REVIEW
Respiratory system is one of the vital systems of the body which is affected negatively by air pollutants, viral and bacterial infections. These infections can lead to several chronic diseases. Modern medicines can help treat these diseases, but they have several side effects that can further lead to other health-related troubles. In India, many people still use herbal remedies to treat mild infec...
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IDENTIFICATION AND VALIDATION OF PALUSTRIC ACID AND ANDROGRAPHOLIDE FROM OCIMUM BASILICUM LEAF AS A PROMISING BREAST CANCER INHIBITOR: AN IN-VITRO AND IN-SILICO ANALYSIS
This study aimed at identifying promising breast cancer inhibitors through in-vitro and in-silico studies. Ocimum basilicum. L is a traditional herb used for varied ailments. The present study is designed to evaluate the anti-carcinogenic potency of Palustric acid and Andrographolide against the MCF-7 cell line by in-vitro analysis. Further in-silico examination was performed to detect and formula...
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PRELIMINARY STUDY OF ANTIMICROBIAL ACTIVITY AND PHENOTYPIC CHARACTER FROM ACTINOMYCETES AND PENICILLIUM SP
Indeed, Actinomycetes and Penicillium are microorganisms that live in different ecosystems. Besides, they play important roles in various fields in respect such as agriculture, medicine and the environment. During this study, we were interested in the isolation of two strains namely: Actinomycetes and Penicillium sp. from coconuts and truffle respectively. In addition, the agar cylinder technique ...
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FABRICATION AND STATISTICAL OPTIMIZATION OF LIPID-BASED NANOPARTICLES FOR THE ENCAPSULATION OF DOLUTEGRAVIR SODIUM
Dolutegravir, an integrase strand transfer inhibitor (INSTI), is a BCS class II, poorly soluble antiretroviral medication that has been licenced by the FDA for the treatment of HIV infections. DTG has a number of drawbacks, including limited oral bioavailability (16%), hepatotoxicity, and instability in an acidic environment. Due to the medication's limited solubility, 84% of the dose is eliminate...
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ANTIDIABETIC ACTIVITY OF METHANOLIC AERIAL EXTRACT OF EUPHORBIA MILII DES MOUL IN STREPTOZOTOCIN–NICOTINAMIDE INDUCED TYPE 2 DIABETIC RATS
It is an ornamental shrub native to Madagascar and the Philippines, widely distributed in India. Euphorbia milii Des Moul is widely used in folk medicine to treat warts (South Brazil), cancer and hepatitis in (China). The present study seeks to evaluate the methanolic aerial extract of Euphorbia milii Des Moul (MAEEM) for its anti-diabetic effect against streptozotocin–nicotinamide induced type ...
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PRODUCTION AND CHARACTERIZATION OF BIOPOLYMER (PHB) USING BACTERIAL STRAINS ISOLATED FROM ALLUVIAL SOIL
Biopolymers are gaining much interest and are considered appropriate substitutes for petroleum-based plastics. It is used for various applications in the medical, agriculture, and packaging fields. The bacterial strains from river soil samples were isolated and screened for biopolymer production. The objective of the present study was to produce polyhydroxybutyrate (PHB) from the isolated strains ...
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MOLECULAR-LEVEL COMPARATIVE ANALYSIS ON HUB-PROTEINS OF PARKINSON’S DISEASE WITH SELECTED SYNTHETIC DRUGS USING AN IN-SILICO APPROACH
Physical interactions between proteins are cardinal to biological processes. To restore their function, proteins must interact with one another. Hub proteins are densely interconnected proteins with a wide range of biological significance and are also to blame for several illnesses, including cancer, autoimmune disorders, and neurodegenerative diseases. The most prevalent of these is Parkinson's d...
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ETHANOPHARMACOLOGY, PHYTOCHEMICALS AND THERAPEUTIC POTENTIAL OF AILANTHUS EXCELSA ROXB: AN OUTLOOK
The genus Ailanthus, which includes both evergreen and deciduous species, is native to both Asia and northern Australia. Traditional medicine relies heavily on this plant, and various components of the plant are utilized to treat a wide range of illnesses. Herbal and ayurvedic drugs have gained worldwide attention over the past decade for their potential health and financial benefits. There are no...
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FORMULATION AND EVALUATION OF NUTRACEUTICAL DRY POWDER SUSPENSION USING MORINGA OLEIFERA LEAVES AND CELASTRUS PANICULATUS SEEDS EXTRACTS
Herbs, which have been used to cure numerous ailments since ancient times, play an important role in building the foundation of modern medications. The present study aimed to investigate the antioxidant potential of nutraceutical dry powder suspension formulated with Moringa oleifera leaves and Celastrus paniculatus seeds extract against DPPH (2,2-diphenyl-1-picryl-hydrazine-hydrate). Plant extrac...
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