Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
MOLECULAR DOCKING ANALYSIS OF PLANT PHYTOCOMPOUNDS AS PROMISING INHIBITORS AGAINST LASB VIRULENCE PROTEIN – AN IN-SILICO AND IN-VITRO APPROACH
Pseudomonas aeruginosa is a Gram-negative pathogenic bacterium that can cause a variety of hospital-acquired diseases. It is a multidrug-resistant bacterium and can survive a wide range of antibiotics; hence there is a concern about its limited therapy options. In this scenario, the discovery and development of novel antibiotics are in high demand. In our research work, molecular docking a Bioinfo...
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1159
DESIGN OF A NOVEL PHOTOBIOREACTOR FOR THE OPTIMIZATION OF GROWTH PARAMETERS OF SCENEDESMUS DIMORPHUS AND UTILIZATION OF DAIRY WASTE FOR BIOENERGY CONVERSION
Scenedesmus dimorphus isone of the widely exploited microalgae in several arenas of science, such as in food, nutraceuticals, agriculture, and pharmaceutical industries due to its high nutritional content and bioactivities. The present study designed a novel, cost-effective, eco-friendly, easy-to-operate and rectangular photobioreactor using glass material. Photobioreactor was provided with monoch...
1614
958
PHYTOCHEMICAL EXPLORATION OF ANISOMELES MALABARICA R. BR. LEAVES BY SOLVENT EXTRACTION AND GC-MS
Medicinal plants belong to the Labiatae family, commonly known as the mint family. This family comprises the Anisomeles malabarica, which contain biologically important phytochemicals. Focus on solvent extraction of selected medicinal plant parts and its phytochemical analysis gives an insight for herbal drug discovery. A heat continuous percolation experiment was conducted for 24 hours using thre...
3436
2011
QUANTITATIVE PHYTOCHEMICAL PROFILE AND IN-VITRO ANTIOXIDANT POTENTIAL OF D5 CHOORANAM, AN ANTIDIABETIC SIDDHA FORMULATION
D5 Chooranam is a classical Siddha formulation developed by Central Council for Research in Siddha, prescribed for the management of diabetes mellitus. The present work was carried out to assess phytochemical profile and also to explore the antioxidant potential of Siddha drug D5 Chooranam. The Phytochemical profile and antioxidant activity were evaluated in five different solvent extracts (Ethyl ...
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1523
EVALUATION OF TRIDAX PROCUMBENS LEAF EXTRACT LOADED PVA FILM FOR WOUND HEALING APPLICATION
Wounds are a severe health problem. The development of pharmaceutical dosage forms to ensure patient comfort and safety and optimize treatment effectiveness is of great interest to the pharmaceutical and biomaterials industries. Tridax procumbens (T. procumbens) leaf is a medicinal herb used for treating wounds since ancient times. In this work, a biomaterial film was developed by using PVA with T...
2875
1511
ANTIDIABETIC ACTIVITY OF METHANOLIC EXTRACT OF DAUCUS CAROTA ROOTS ON ALBINO WISTAR RAT
Objective: The study's key objective is to evaluate the Antidiabetic activity of methanolic root extract of Daucus carota in normal, streptozotocin-induced Diabetic, and alloxan-induced diabetic rats. Materials and Methods: Albino Wistar rats were administered at a dose of streptozotocin 50mg/kg /day and alloxan monohydrate 150mg/kg/day i.p. for 30 days. Experimental rats were given Daucus carota ...
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872
ANTIMICROBIAL POTENTIAL OF CRUDE EXTRACTS AND FATTY ACID FRACTIONS OF FOUR PTERIDOPHYTE SPECIES FROM ASSAM, NORTHEAST INDIA, AND THEIR IDENTIFICATION BY GC-MS
Fatty acids produced by plants protect themselves from pathogens, such as multidrug-resistant bacteria. In the present work, crude extracts, and fatty acid fractions of four pteridophyte species from Assam, Northeast India, were evaluated for their antimicrobial properties, and the bioactive compounds were identified using GC-MS analysis. The crude extract of Pteris semipinnata (Ps), Lygodium micr...
1627
1335
ANTIEPILEPTIC EFFECT OF TELMISARTAN AND VALSARTAN ALONE AND IN COMBINATION WITH ETHOSUXIMIDE ON PENTYLENETETRAZOL INDUCED EXPERIMENTAL MODEL OF EPILEPSY IN ALBINO MICE
Epilepsy is a common neurological disorder in clinical practice requiring newer targets for its efficient treatment. Recently, brain renin-angiotensin system has gained immense importance because of its involvement in seizure regulation. Hence, the present study was planned to evaluate whether angiotensin II AT1 receptor antagonists possess anticonvulsant activity in experimental animals. Forty- e...
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748
MOLECULAR DESIGN AND DOCKING STUDY OF NOVEL QUINOXALINE-CONTAINING COMPOUNDS AS PI3K/MTOR DUAL INHIBITOR
The PI3K-AKT-mTOR signaling pathway is widely used in cancer therapy as it is a signaling pathway that is frequently disrupted in human cancers. Increasingly, inhibitors develop against key proteins in signaling pathways, such as PI3K and mTOR. Dual inhibitors targeting PI3K and mTOR are more potent than one inhibitor targeting only a single protein. This study used to design and molecular docking...
1544
956
NEUROPROTECTIVE POTENTIAL OF ETHANOLIC ASHWAGANDHA ROOT EXTRACT, DOXYCYCLINE AND ELLAGIC ACID AGAINST ROTENONE INDUCED PARKINSON’S DISEASE: A IN-VIVO MODEL STUDY
Parkinson's disease (PD) is the second most prevalent type of neurodegenerative disorder and is a chronic, progressive condition. In the current investigation, we used a rotenone (ROT)-developing rat model of PD to assess the neuroprotective efficacy of ethanolic Withania somnifera root extract (EWSR) in comparison to the known neuroprotectants i.e., Doxycycline (Doxy), and ellagic acid (EA) indiv...
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