Posted by admin on Aug 31, 2023 in |
Microbes are widespread and have been studied widely in recent years. Disease-causing microbes can also be called pathogens, germs, or bugs. These microbes are responsible for causing infectious diseases. Microbes are mediators in almost all ecosystem processes and act as a global pivotal game changer in various ecological activities. The therapeutic outcome with antimicrobial drugs depends totally on the selection of antimicrobial drugs. The choice of antimicrobial drugs depends on causative agents, patient factors, and clinical pharmacology of antimicrobial agents. The current review discusses how microbes can enter the human body through different sites and how antimicrobial drugs help cure various infectious diseases. Along with the same, the current review also represents how antimicrobial drugs affect the viability of microorganisms. The article also incorporates the prophylactic use of antimicrobial drugs. The main objective of the current review article is to give detailed knowledge about single, binary and tertiary combinations of antimicrobial drugs, analytical methods, and patent search of these...
Read More
Posted by admin on Aug 31, 2023 in |
The development of Nanotechnology has paved the way to study various nanomaterials. Nanoparticles are structures that measure the size from 1-100nm. Widely used nanoparticles are usually prepared using noble metals, that is, gold, silver, palladium, and platinum. At the same time, they find their way into a wide range of applications in medicine, electronics, energy saving, environment, textile, cosmetics, biomedical, etc. The natural reducing agents in plants, such as carbohydrates, flavonoids, etc., reduce the silver, generating potential silver nanoparticles. Silver nanoparticles are intended to be used for the present study generated through green synthesis using millets. Millets are small-seeded grasses that are hardy and grow well in dry zones as rain-fed crops under marginal conditions of soil fertility and moisture. The different varieties of millets intended to be used in the project are Barnyard millet, Finger millet, Foxtail millet, Kodo millet, little millet, Pearl millet, Prosomillet, Sorghum. The Silver nanoparticles synthesized through an aqueous extract of different varieties were checked for their quality using UV-VIS spectrophotometer and Scanning electron...
Read More
Posted by admin on Aug 31, 2023 in |
An example of the human microbiota is Staphylococcus saprophyticus, a gram-positive, non-hemolytic pathogenic bacterium. It’s a prevalent culprit behind simple infections associated with the urinary tract, especially among sexually active young women. It has a high colonization rate in the perineum, rectum, urethra, cervix, and gastrointestinal system and is also quite lethal. Because of their ability to form a biofilm, these bacteria are highly resistant to antibiotics. Thus, unconventional methods, such as the use of silver nanoparticles, have been devised to counteract this type of biofilm. The silver nanoparticles are produced in an environmentally friendly way by utilizing an extract of water from banana peels. UV/Vis, FTIR, SEM, and EDAX are the four methods used to characterize the NPs and validate their production. Using the Screening method and SEM analysis, we show that silver nanoparticles inhibit the growth of Staphylococcus saprophyticus ATCC 15305, the most prevalent bacteria responsible for urinary tract infections....
Read More
Posted by admin on Aug 31, 2023 in |
Background: Prescription audit is an effective way to raise the standard of prescriptions. WHO core prescribing indicators are established and trustworthy tool for assessing the quality of prescriptions. So, we used WHO-recommended core prescribing indicators to assess the prescription pattern of treating physicians. Methods: A retrospective observational study was done. A total of 632 prescriptions were included with 2002 drugs from general medicine OPD. The prescriptions were analyzed for general details, legibility, rationality, and WHO core prescribing indicators. The data obtained were presented as descriptive statistics by using MS-Excel and SPSS ver.24. Results: All the prescriptions had general details mentioned as pre-printed. The average number of drugs per encounter was 3.17 ± 1.64 and only 461 (23.03 %) of the drugs were prescribed by generic name. The percentage of encounters prescribed with an antibiotic 160 (25.3%) and an injection 164 (25.9%) was observed. A total 1767 out of 2002 (88.3%) of the drugs were prescribed by the NLEM. Prescriptions with diagnosis (77%), signed (83.07%), and 61.07% with legible handwriting...
Read More
Posted by admin on Aug 31, 2023 in |
D5 Chooranam is a classical Siddha formulation developed by Central Council for Research in Siddha, prescribed for the management of diabetes mellitus. The present work was carried out to assess phytochemical profile and also to explore the antioxidant potential of Siddha drug D5 Chooranam. The Phytochemical profile and antioxidant activity were evaluated in five different solvent extracts (Ethyl acetate, chloroform, ethanol, petroleum ether, and water) of D5 Chooranam. The phytochemical analysis of D5 Chooranam disclosed the existence of various phytochemicals in D5 Chooranam. The amount of phytochemicals present in D5 Chooranam also correlates with the various pharmacological activities as per its therapeutic indications. The considerable radical scavenging capacity of D5 Chooranam, particularly in its water extract, ethyl acetate extract, and fresh aqueous solution, is well justified by the results of all in-vitro antioxidant studies. These results reveal the beneficial effect of D5 Chooranam against oxidative stress associated disorders like diabetes mellitus and its complications. Hence it can be concluded that it may be due to the presence of vital...
Read More
