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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

Inclusion in Web of Science (Thomson Reuters) - ESCI
Projected Impact Factor (2018): 0.83 , CiteScore (2017): 0.27
Five-Year Projected Impact Factor: 1.81

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Volume 1 (2010) - Issue 6, June

Review Articles

 
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1.

IN PRAISE OF THE HUMBLE MUSHROOM CORDYCEPS MILITARIS

Cordyceps militaris is an important medicinal mushroom useful for the extraction of several bio-metabolites for natural drugs to revitalize the various physiological systems of the body from the ancient era. The constituents of C. militaris are now using widely in the modern pharmaceutical industries. The active principles of C. militaris are beneficial to act principally as pro-sexual, anti-cance...

Shonkor Kumar Das*, Mina Masuda and Akihiko Sakurai

Department of Applied Chemistry and Biotechnology, Graduate School of Engineering, University of Fukui, 3-9-1 Bunkyo, Fukui, Japan

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).1-6

1-6

1928

949

2.

A NOVEL APPROACH IN GASTRO RETENTIVE DRUG DELIVERY SYSTEM: FLOATING DRUG DELIVERY SYSTEM

The task of achieving efficient delivery of drugs that have poor bioavailability or narrow absorption windows have plagued the pharmaceutically industry for decades. Thus, much research has been dedicated to the development of novel polymeric-based gastro retentive drug delivery technologies that may optimize the bioavailability and subsequent therapeutic efficacy of such drugs. Several technical ...

Samip Shah * and Shridhar Pandya

Department of Pharmaceutics, Pioneer Pharmacy Degree College , Vadodara (Gujarat), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).7-18

7-18

2284

1048

3.

COCONUT OIL: THE HEALTHIEST OIL ON EARTH

Coconut oil is said to be healthiest oil on the earth because it is used not only diabetes but it is also used to reduce weight, risk of atherosclerosis, risk of cancer, prevents bacterial, viral and fungal infections, improves digestion and nutrient absorption etc. Diabetes is all about sugar, the sugar in our bodies known as blood sugar or blood glucose. There is one fat that diabetics can consu...

Aakansha Gupta*, Annu Malav, Anoop singh, M.K.Gupta, Mahaveer Pr. Khinchi, Natasha Sharma and Dilip Agrawal

Kota College of Pharmacy, RIICO Industrial Area, Ranpur, Kota (Rajasthan), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).19-26

19-26

3257

1193

4.

AROMATASE INHIBITORS: A NEW HOPE FOR BREAST CANCER PATIENTS

Breast Cancer is the leading cause of mortality among the women of age 30 to 60. Endocrine therapy used for the treatment has shown promising results in which the anti-estrogen tamoxifen has been the standard first-line treatment used for more than 30 years. But its side effects like resistance, increase risk of thromboembolism, endometrial cancer and uterine sarcoma limits its use. The developmen...

Anu Mahajan *, Shruti Rawal, PMS Bedi, Nipun Mahajan and Ajay Sharma

Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).27-40

27-40

1631

489

Research Articles

 
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5.

FORMULATION AND EVALUATION OF CELECOXIB –LOADED NANOSIZED EMULSION AS TRANSDERMAL DRUG DELIVERY VEHICLE

Celecoxib, a selective cyclo- oxygenase – 2 inhibitor has been recommended orally for the treatment of arthritis and osteoarthritis. Long term oral administration of celecoxib produces serious gastrointestinal side effects. Therefore the aim of the present investigation was to assess the potential of nanosized emulsion formulations for transdermal delivery of celecoxib (CXB), to reduce the side ...

R. Baskar, S. Joseph Raj, M. Rajesh *, l. Subramanian, S. Palanichamy and A. Thangathirupathi

Department of Pharmaceutics, Sankaralingam Bhuvaneswari College of Pharmacy, Anaikuttam, Sivakasi, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).41-49

41-49

1717

595

6.

SYNTHESIS OF 3- (1 – BENZYL – 1H – BENZO [D] IMIDAZOL – 2 – L AMINO) – 2 – (3 – ARYL – 1- PHENYL – 1H – PYRAZOL – 4 – YL) THIAZOLIDIN – 4- ONES AND THEIR ANTIMICROBIAL ACTIVITIES

Reaction of 1- (1- benzyl- 1H- benzo [d] imidazol- 2- yl) hydrazine (1) with 3-aryl-1-phenyl-1H-pyrazole-4-carbaldehydes (2a-f) in ethanol yielded the corresponding Schiff bases (3a-f). Further, cyclization of compounds 3a- f with thioglycollic acid in benzene in presence of anhydrous ZnCl2 furnished desired novel compounds 3- (1 – Benzyl - 1h - Benzo [D] Imidazol – 2 - L Amino) – 2 - (3 –...

Sharanabasappa B. Patil and Naganna M. Goudgaon*

Department of Studies and Research in Chemistry, Gulbarga University, Gulbarga (Karnataka), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).50-56

50-56

1361

582

7.

DEVELOPMENT AND CHARACTERIZATION OF TRANSDERMAL MICROEMULSION GEL FOR AN ANTIVIRAL DRUG

The objective of this study was to design and develop o/w microemulsion for transdermal delivery of poorly water soluble acyclovir by aqueous titration method. Oleic acid: castor oil (3:1), tween 80, and ethanol were selected as oily phase, surfactant and cosurfactant respectively. The Pseudoternary phase diagrams were constructed by aqueous titration method. The cosurfactant affect the shape and ...

Brajesh Kumar *, Sanjay Kumar Jain, Sunil Kumar Prajapati, Alok Mahor and Ajay Kumar

Institute of Pharmacy, Bundelkhand University, Jhansi (UP), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).57-74

57-74

2382

618

8.

RP- HPLC METHOD FOR THE ESTIMATION OF ESOMEPRAZOLE MAGNESIUM IN BULK AND ITS PHARMACEUTICAL DOSAGE FORMS

A simple reverse phase HPLC method was developed for the determination of Esomeprazole magnesium present in bulk and pharmaceutical dosage forms. Efficient chromatographic separation was achieved on Kromasil100-C18 stationary phase (250 X 4.6 mm i.d., 5µ particle size) with simple mobile phase combination of acetonitrile: phosphate buffer 55: 45 (V/V) in an isocratic mode at a flow rate of 1.0 mL...

Girish G. Rathi, Rakesh Kumar Singh*, Pankaj Singh Patel, Rajan Kumar Singh and Brijesh Kumar

College of Pharmaceutical Sciences, Mohuda, Berhampur, Orissa, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).75-81

75-81

1604

612

9.

FORMULATION AND OPTIMIZATION OF SUSTAINED RELEASE TABLETS OF DICLOFENAC SODIUM USING GUAR GUM AS RELEASE MODIFIER

PURPOSE OF STUDY: In the present study, an attempt was made to increase therapeutic effectiveness, reduction in dosing frequency and thus improving patient compliance, by developing sustained release matrix tablets of Diclofenac sodium using guar gum as release modifier. METHOD: Six batches of sustained release matrix tablets of Diclofenac sodium was prepared by using different drug: polymer ra...

Rishabha Malviya*, Pranati Srivastava, Mayank Bansal and Pramod Kumar Sharma

Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut (UP), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).82-88

82-88

2462

955

10.

PHARMACOGNOSTICAL INVESTIGATION OF RICINUS COMMUNIS STEM

Castor (Ricinus communis L, Euphorbiaceous) is needed in the United States to supply caster oil for the hundred of products using this versatile chemurgical raw material. 40-45 thousand tons of castor oil and derivatives are imported each year. Ricinus communis is a common medicinal plant in Ayurveda and is used several part of country for various medicinal properties like the oil of leaf and root...

Ramesh Kumar Singh *, M. K. Gupta, Arvind Kr. Singh and Sunil Kumar

Department of Pharmacy, Rameshwaram Institute of Technology & Management, Lucknow (UP) India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).89-94

89-94

1675

863

11.

DEVELOPMENT AND VALIDATION OF SPECTROFLUORIMETRIC METHOD FOR THE ESTIMATION OF VOGLIBOSE IN BULK AND PHARMACEUTICAL DOSAGE FORM

A simple, accurate, sensitive, reproducible and cost – effective spectrofluorimetric method was developed for the estimation of voglibose in bulk and pharmaceutical formulations. The solvent systems, wavelengths of detection (excitation and emission) were optimized in order to maximize the sensitivity and minimize the cost of analysis for voglibose. Derivatization procedure was employed for anal...

Mallikarjuna Rao N.*, Bagyalakshmi J. and Ravi T. K.

College of Pharmacy, Sri Ramakrishna Institute of Paramedical Science, New Siddapudur, Coimbatore, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).95-01

95-101

1720

684

12.

ANTI-DIABETIC ACTIVITY OF PSORALIA CORYLIFOLIA SEED EXTRACT IN ALLOXAN INDUCED DIABETIC RATS

Psoralia corylifolia commonly known as Babchi, Bavachi in Hindi, is a well known herb in Indian system of medicine to treat various disorders including diabetes mellitus without any scientific evidences. Therefore this study was designed to investigate in vivo hypoglycemic and antidiabetic potential of methanolic extract of seeds of Psoralia corylifolia in glucose loaded animals and alloxan induce...

Anurag Mishra*, Rajiv Gupta and Rahul Dev Lawania

Department of Pharmacognosy, Faculty of Pharmacy, Babu Banarasi Das National Institute of Technology and Management, Lucknow, (U P) India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).102-08

102-108

1392

533

13.

ANTIDIABETIC ACTIVITY OF BERBERIS ASIATICA (D.C.) ROOTS

Barberries are a large group of evergreen shrubs, found in Lalitpur, Allahabad, Bhopal and Haldwani etc. It is an evergreen shrub. Commonly, its fruits are called as berries. This plant is generally use in case of diabetes and mouth ulcer, as a traditional use. Type 2 diabetes mellitus (formerly called NIDDM, type II or adult-onset) is characterized by insulin resistance in peripheral tissue and a...

Pradeep Singh*, S. K. Jain and Shashi Alok

Department of Pharmacognosy, Institute of Pharmacy, Bundelkhand University, Jhansi (UP), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(6).109-12

109-112

1479

564