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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

Inclusion in Web of Science (Thomson Reuters) - ESCI
Projected Impact Factor (2017): 0.59 , SJR (2017): 0.14
Five-Year Projected Impact Factor: 1.83

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Volume 1 (2010) - Issue 7, July

Review Articles

 
Title
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1.

RATIONALE BEHIND THE COMBINATION OF SULFONYLUREA AND METFORMIN IN DIABETES MELLITUS

The prevalence of diabetes in India has been growing by leaps and bounds. The statistics in this regard are quite alarming. It is obvious that in a country like India, the rising prevalence of diabetes with its complications is likely to produce severe constraints on health care budgets in future. This explosion of diabetes in India has been viewed with serious concern by the WHO and the Internati...

PV Ingle * and G S Talele

Department of Clinical Pharmacy, R. C. Patel Institute of Pharmaceutical Education & Research 1, Shirpur, Dist- Dhule, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).1-5

1-5

1923

710

2.

A COMPREHENSIVE PHARMACOGNOSTIC REPORT ON VALERIAN

Herbalism is a traditional medicine practice based on the utilization of plants and plant extracts. In herbalism ‘Valerian’ is a boon medicine for several ailments. Valerian (Valerian officinalis) is a naturally occurring Ayurvedic medicine widely grown in the temperate zones of Europe, North America and Asia and is a safe herbal supplement indicated in various ailments, chief being for the sy...

Muktika Sharma , U. K. Jain *, Ajay Patel and Nilesh Gupta

Department of Pharmacy, Bhopal Institute of Technology and Science, Suveesha Vidyanagar, Bhojpur Road, Bangrasia, Bhopal (MP) India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).6-40

6-40

2861

1611

Research Articles

 
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3.

IN VITRO PROPHYLACTIC CATARACT PREVENTION STUDY ON GLUCOSE INDUCED CATARACT BY QUERCETIN AND ALPHA- TOCOPHEROL

The antioxidants such as quercetin and alpha- tocopherol were subjected for in vitro prophylactic cataract prevention study on glucose induced cataract model. Goat lenses were incubated in artificial aqueous humor containing 55 mM glucose with test drugs in different concentrations at room temperature for 72 h. Biochemical parameters studied in the lens were electrolytes (Na+, K+), Na+- K+- ATPase...

Lokesh J Shetty *, Harikiran H and A Sharma

Department of Pharmacology and Pharma Chemistry, Shree Devi College of Pharmacy, Kenjar, Mangalore, Karnataka, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).41-45

41-45

1197

469

4.

DEVELOPMENT AND EVALUATION OF FAST DISINTEGRATING TABLETS OF SALBUTAMOL SULPHATE BY SUPERDISINTEGRATING AGENTS

The purpose of this research was to develop fast disintegrating tablets of Salbutamol Sulphate using superdisintegrating agents. Recently fast disintegrating drug delivery system have started gaining popularity and acceptance as new drug delivery system, because they are easy to administer and lead to better patient compliance. Salbutamol Sulphate is a selective β2 receptor agonist widely used as...

Arvind K. Singh *, Ramesh K. Singh, Sunil Kumar and M. K. Gupta

Department of Pharmacy, Rameshwaram Institute of Technology & Management, Lucknow (UP), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).46-53

46-53

1418

566

5.

SAFETY AND MULTIPLE DOSE PHARMACOKINETICS OF PALIPERIDONE ER IN INDIAN SCHIZOPHRENIC PATIENTS

Paliperidone is a new active substance, belonging to the class of atypical antipsychotic, and is the active metabolite of a well-known active substance, risperidone that has been used for the last 3 years. A randomized, double-blind, multicentric, study to evaluate the safety and efficacy of Paliperidone ER compared to Olanzapine in patients with Schizophrenia was conducted in Indian schizophrenic...

HR Mehta*, AS Srivastava, SK Shah, DS Patel, PG Labana, AK Ramani, PB Patel and BB Patel

Clinical Research Group, Torrent Research Centre, Village-Bhat, Gandhinagar, Gujrat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).54-61

54-61

1310

484

6.

ANTIOXIDANT AND PHYTOCHEMICAL POTENTIAL OF WILD EDIBLE MUSHROOM TERMITOMYCES RETICULATUS: INDIVIDUAL CAP AND STIPE COLLECTED FROM SOUTH EASTERN PART OF INDIA

Antioxidant and phytochemical properties of an ethanolic extracts from the wild edible mushroom Termitomyces reticulatus and their individual parts (Cap and Stipe) were evaluated. Reducing power, β-carotene bleaching, ABTS and DPPH radicals scavenging activity were used to evaluate their antioxidant activity. Antioxidant components like total phenol, flavonoid, β-carotene and lycopene were also ...

Jagadish K. Loganathan *, D. Gunasundari, M. Hemalatha, R. Shenbhagaraman and V Kaviyarasan

Center for Advanced Studies in Botany, University of Madras, Guindy Campus, Chennai (TN), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).62-72

62-72

1692

608

7.

A QUALITY ASSESSMENT AND PHYTOCHEMICAL SCREENING OF SELECTED REGION OF WITHANIA SOMNIFERA DUNAL

Withania somnifera Dunal. (ashwagandha) is widely used in Ayurvedic medicine, the traditional medicinal system of India. It is an ingredient in many formulations prescribed for a variety of musculoskeletal conditions (e.g., arthritis, rheumatism), and as a general tonic to increase energy, improve overall health and longevity, and prevent disease in athletes, the elderly, and during pregnancy. In ...

Brijendra Kr. Singh *, Rajat Gahoi and Anuj Sonkar

School of Pharmaceutical Sciences, Shobhit University, Meerut, UP, (India)

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).73-77

73-77

1516

525

8.

HYDROALCOHOLIC EXTRACTION OF MANGIFERA INDICA (LEAVES) BY SOXHLETION

The genus Mangifera indica belongs to the family Anacardiaceae and comprises of 40 species distributed in tropical and sub-tropical parts of South East Asia, Africa and Latin America The resin is useful in cutaneous disease .the juice of kernel is snuffed to stop nasal bleeding. A decoction of the leaves with a little honey added is given in aphonia, the loss of voice. Mid ribs of the leaves calci...

S B Nikhal* and PA Dambe

Department of Pharmacognosy, Siddhant College of Pharmacy, Sudumbre, Pune (Mh), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).78-81

78-81

4046

1295

10.

BLOOD CHOLESTEROL LOWERING EFFECT OF ADENANTHERA PAVONINA SEED EXTRACT ON ATHEROGENIC DIET INDUCED HYPERLIPIDEMIA RATS

The effect of Adenanthera pavonina (AP) seed extract on the blood cholesterol level of atherogenic diet rats was evaluated. Twelve adult male Wistar rats divided into 3 groups of 4 animals each were used and were treated orally with normal saline (Control group), atherogenic diet (Positive control) and 200mg/kg of AP seed extract (treatment) over a 4-week period. The present study was undertaken t...

Vettae Gounder Maruthappan * and Kumaravelu Sakthi Shree

Unit of Endocrinology, Department of Zoology, Bharathiar University, Coimbatore, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).87-94

87-94

1338

625

11.

IMPROVEMENT OF DISSOLUTION BEHAVIOR OF PARACETAMOL USING SOLID DISPERSION TECHNIQUE

Paracetamol is an important anti-inflammatory and analgesic drug widely used in biological disorders. One of major problems with this drugs is its low solubility thus dissolution rate in biological fluid, which results into poor bioavailability after oral administration. In this study polyvinyl pyrrolidone (PVP) is used to enhance bioavailability of paracetamol. Paracetamol and PVP are used in 1:1...

Rishabha Malviya*, Pranati Srivastava, Mayank Bansal and Pramod Kumar Sharma

Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut (UP), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).95-99

95-99

2258

622

12.

NOVEL METHOD FOR SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN HYDROCHLORIDE AND OFLOXACIN BY REVERSE PHASE-HIGH PERFORMANCE LIQUID CHROMATOGRAPHY (RP-HPLC)

A novel method was developed for the determination of fluoroquinolones such as ciprofloxacin hydrochloride (CPL) and ofloxacin (OFX) by isocratic reverse phase-high performance liquid chromatography (RP-HPLC) coupled with UV detection. The developed method was rapid, accurate, reproducible, economical and sensitive for the simultaneous estimation of ciprofloxacin hydrochloride and ofloxacin. Fluor...

Neetu Sachan *, Phool Chandra, S. K. Saraf and R. C. Gupta

College of Pharmacy, Institute of Foreign Trade & Management (IFTM), Lodhipur Rajput, Delhi Road, Moradabad (UP), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).100-07

100-107

1163

456

13.

PHYTOCHEMICAL SCREENING ON THE STEM BARK OF ANTHOCEPHALUS CADAMBA (ROX B.) MIQ.

The present work deals with development and standardization of phytochemical screening for quantification of methanolic extract of medicinal plant stem bark of Anthocephalus cadamba (Roxb.)Miq. The scientific parameter is necessary to identify the exact plant material and to find its quality and purity. The present study deals with various, physical evaluation and preliminary phytochemical screeni...

Himanshu Gurjar *, S. K. Jain, Rupali Nandanwar and Vinod K. Sahu

Department of Pharmacognosy, Institute of Pharmacy, Bundelkhand University, Jhansi (UP), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).108-15

108-115

1972

882

14.

ANTI BACTERIAL ACTIVITY OF 3- (4- ARYL SUBSTITUTED- 3 – YL) – THIAZOLIDIN- 4 – ONE AND THEIR DERIVATIVES

This study involves synthesis of 3- [4- aryl substituted- 3 - yl] - thiazolidin- 4 – one - 5- acetic acid by microwave oven induced synthesis method. Synthesized compounds were screened for anti-microbial activity by MIC and zone inhibition tests against various gram positive organism and gram negative organisms respectively. The microbiological assay is based upon a comparison of the inhibition...

M R Shivalingam *, D Jeslin, Y V Kishore Reddy, B Appa Rao, N Sunitha, Velpuri Amulya and T Jyothibasu

Department of Pharmaceutics, Victoria College of Pharmacy, Guntur, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).116-22

116-122

1301

528

15.

OPTIMIZATION OF EFFECT OF SUPERDISINTEGRANTS AND SUBLIMING AGENT ON ORODISPERSIBLE TABLET OF ONDANSETRON RESINATE

Ondansetron is a serotonin 5HT3 antagonist; anti emetic drug. Bitter taste of the ondansetron is a major problem in ensuring patient compliance. Resinates of ondansetron were prepared with Indion 234 and loading process was optimized. A 3² factorial design was used for formulation development of orodispersible tablet of these taste masked resinates. The amount of subliming agent (camphor) and sup...

Shridhar Pandya* and Samip Shah

Department of Pharmaceutics, Pioneer Pharmacy Degree College, Vadodara (Gujrat), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(7).123-31

123-131

1192

454