Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
PICOGRAM LEVEL QUANTIFICATION OF VARENICLINE IN HUMAN PLASMA SAMPLES BY LC–ESI-MS/MS
The objective of this research was to develop and validate a simple, sensitive and specific Liquid Chromatography – Tandem Mass Spectrometry (LC–MS/MS) quantification of Varenicline in human plasma using Varenicline -D4 as Internal Standard (IS). The analyte was separated on a Zorbax SB-C18, 4.6 x 75 mm, 3.5 μm, 80 Å column with an isocratic mobile phase of 5mM ammonium formate: acetonitrile...
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STUDY OF VARIATION IN PRICE OF VARIOUS NSAIDS COMBINATIONS AVAILABLE IN INDIAN MARKET
Introduction: Non Steroidal Anti Inflammatory drugs are widely used drugs worldwide for various inflammatory conditions and acute as well as chronic pain conditions. In India large number of NSAIDs preparations are available in the market. Therefore choosing a NSAID becomes very difficult task for the prescribing physician. Objective: To evaluate the price variation of the different NSAIDs prepara...
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STUDY OF NEUTRALIZATION OF ENZYMATIC ACTIVITY OF DABOIA RUSSELII VENOM BY VARIOUS PLANT EXTRACTS AND THEIR COMBINATIONS USING IN VITRO METHODS
Snakebite is an important cause of morbidity and mortality and is one of the major health problems in India. Russell’s viper (Daboia russelli) appears to be the commonest cause of fatal snakebite in many Asian countries and especially in the Indian subcontinent. Intravenous administration of anti venom serum neutralizes the systemic actions, but it is of little effect on the reversal of local sy...
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EVALUATION OF ANTI- HYPERGLYCAEMIC ACTIVITY OF MAYTENUS EMARGINATUS WILLD LEAVES EXTRACT ON STREPTOZOTOCIN-INDUCED DIABETES IN WISTAR RATS
Maytenus emarginatus Willd. Celeastraceae, popularly known as “Kankeri or kankero”, is a Thorny staff evergreen tree that is rich in various chemical constituents that determine the medicinal potential of this species. Diabetes mellitus is a disease that is affecting major population of the world. This study aimed to evaluate the antihyperglycaemic activity of the hydroalcoholic extract of the...
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EFFECT OF ORAL ADMINISTRATION OF VITAMIN A ON BLOOD GLUCOSE LEVEL IN RABBITS AND ITS POSSIBLE INTERACTIONS WITH COMMONLY USED ORAL ANTIDIABETIC AGENTS
In diabetes mellitus antioxidant vitamins are commonly employed to prevent or mitigate the long term complications of the disorder. Diabetic retinopathy, nephropathy, coronary and cerebral vascular insufficiency are examples of such complications. They are more common in Type 2 diabetes mellitus. The present study was conducted to observe the effect of Vit A on blood glucose level and its possible...
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PHYTOCHEMICAL INVESTIGATION FOR THE WOUND HEALING POTENTIAL OF A NOVEL COMPOUND ISOLATED FROM MENTHA PIPERITA L. LEAVES
Mentha piperitais currently one of the most economically important aromatic and medicinal crops in all over the world. Phytochemical investigation of the leaves of Mentha piperita (L.) (Lamiaceae) yielded a new compound, which is decarboxyrosemarinic acid galactoside. Formulate as 3’, 4’-dihydroxy-β-phenyl ethyl caffeate-4-(3’’’-menthyl)-4’-β-D-galacto pyranoside. 13C NMR, 1H NMR, FA...
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COMPARATIVE PHARMACEUTICAL QUALITY CONTROL TESTING OF DIFFERENT BRANDS OF PARACETAMOL TABLETS AVAILABLE IN THE TRINIDAD & TOBAGO, WEST INDIES
Paracetamol tablets are popular over the counter (OTC) products among the patients as a good analgesics and antipyretics. The objective of this study was to compare the quality of the paracetamol tablet formulations those are locally available in Trinidad & Tobago pharmaceutical market manufactured by various pharmaceutical companies with pharmacopoeia standards. The four popular brands (A, B,...
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SIMULTANEOUS ESTIMATION OF ALFUZOSIN AND DUTASTERIDE IN TABLET DOSAGE FORM BY REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY
A simple, accurate, economic and rapid method for the simultaneous estimation of Alfuzosin and Dutasteride by RP-HPLC, as a result simple, economic, precise and accurate methods was developed and validated by Reverse Phase High performance Liquid Chromatography in tablet dosage form. The mobile phase consisted of Acetonitrile and Buffer solution in the ratio of (75:25) was eluted through universil...
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2D QSAR STUDY OF POTENT GSK 3β INHIBITOR FOR TREATMENT OF TYPE II DIABETES
The best QSAR model were generated with left of adept and significant descriptors like electronic, lipophilic and topological, using multiple linear regression (MLR) and partial least square (PLS), model further explained by using forward feed neural network analysis (FFNN). QSAR is a kind of technique that directly correlates in between chemical structure to their biological activity. The best ML...
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ANTIMICROBIAL ACTIVITY OF LEUCAS CEPHALOTES SPRENG
Medicinal plants are of important therapeutic aid for various treatments. Leucas cephalotes Spreng. up in cultivated fields as a weed, especially after a period of rain. In the present study the dried plant stems powder of Leucas cephalotes Spreng. was taken and subjected to extraction with ethanol and aqueous extraction was done on the marc left after ethanolic extraction. The antimicrobial activ...
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