Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SYNTHESIS, CHARACTERISATION AND PHARMACOLOGICAL EVALUATION OF NOVEL COUMARIN DERIVATIVES
In the present study a new series of coumarin derivatives have been synthesized by condensation of ethyl acetoacetate and resorcinol. The chemical structures of the synthesized compounds were confirmed by means of IR, 1H-NMR and Mass spectral analysis. These compounds were screened for their Analgesic and Anti-inflammatory activities. Among the synthesized compounds II (a-1 to c-3)....
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A STUDY ON ANTIMICROBIAL POTENTIAL OF TRIDAX PROCUMBENS (L.) AGAINST CLINICAL ISOLATES
In-vitro antibacterial and antifungal activity of Tridax procumbens plant parts (leaf and stem) were investigated by agar well diffusion method. The petroleum ether, methanol and aqueous extracts of the plant parts were tested against two bacterial strains i.e., Bacillus subtilis and Escherichia coli and two fungal strains i.e., Trichoderma reesei and Fusarium oxysporium. The results of antibacter...
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ANTIOXIDANT POTENTIAL FRACTIONATION FROM METHANOL EXTRACT OF AERIAL PARTS OF RUELLIA PROSTRATA POIR (ACANTHACEAE)
Aerial parts of Ruellia prostrata were subjected to extraction and further fractionation to obtain antioxidant rich fraction. Different concentrations of methanolic extract and its n-butanolic fraction were subjected to antioxidant assay by DPPH method, Nitric oxide scavenging activity and reducing power assay. The fractions showed dose dependent free radical scavenging property in all the models....
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HIGH PREVALENCE OF HOOKWORM INFECTION AND APPARENT ABSENCE OF ASCARIS LUMBRICOIDES: A CASE STUDY AT THE KOMFO ANOKYE TEACHING HOSPITAL IN GHANA
Background: Parasitic helminth infection is one of the major risk factors underlying the high rates of anaemia and malnutrition in many third world countries due to the poor socio-economic and environmental conditions of the people and these play a very significant role in their transmission. Method: 2000 stool specimens collected between May and October 2008 at the Komfo Anokye Teaching Hospit...
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FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF GRANISETRON HYDROCHLORIDE BY DRY GRNULATION METHOD
The aim of work is to characterization and evaluation of fast dissolving tablet of Granisetron hydrochloride using three superdisintegrants like crosscarmellose sodium, crosspovidone and sodium starch glycolate. FTIR studies revealed that there was no physico-chemical interaction between granisetron hydrochloride and other excipients. The tablets were prepared by dry granulation method and all had...
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APPLICATION OF DESIGN OF EXPERIMENTS FOR OPTIMIZATION OF RANEY NICKEL MEDIATED BORROWING HYDROGEN REACTION
An efficient, cost effective use of Raney nickel (R-Ni) a widely used industrial catalyst for N-Alkylation using alcohols is highlighted here. The work describes the scope and capability of R-Ni in borrowing hydrogen reactions for Aniline and Benzyl alcohol. The reaction optimization is described using two techniques, Conventional and Design of experiment. The use of DOE for reaction optimization ...
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PHARMACOGNOSTIC AND PHYTOCHEMICAL INVESTIGATION ON STEM BARK OF CHLOROXYLON SWIETENIA DC. AN ETHNOMEDICINALLY IMPORTANT MEDICINAL TREE
Chloroxylon swietenia DC. belongs to the family Rutaceae / Meliaceae / Chloroxylaceae, is a medicinal and aromatic tree of dry deciduous forests. It is popularly known as Yellow wood, East Indian satin wood and Ceylon satin wood. The stem bark is credited for its effectiveness in the treatment of common cough and cold, it is also used as an astringent. Its pharmacognostic data for authentication o...
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EFFECT OF PLACEBO ON DEPRESSION
Depression is a well defined mood disorder which is characterized by state of disposition of mind and dislike or antipathy to activity that can affect an individual’s thoughts, demeanor, sense of emotional touch and physical well- being. Depressed people may feel mournful, troubled, uneasy in mind, meaningless, helpless and unworthy, experiencing as if having committed an offence. They are easil...
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SYNTHESIS, CHARACTERISATION AND ANTIMICROBIAL EVALUATIONS OF SOME NOVEL 1, 3, 4-THIADIAZOLE DERIVATIVES
A series of 1, 3, 4-thiadiazole derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR and mass spectrum analysis. All the compounds were evaluated for antibacterial and antifungal activities. Most of the compounds have shown significant antibacterial and antifungal activity when compared with the standard drugs...
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DEVELOPMENT & VALIDATION OF AN IN VITRO DISSOLUTION METHOD WITH HPLC ANALYSIS FOR BETAMETHASONE ACETATE AND BETAMETHASONE SODIUM PHOSPHATE IN FORMULATED DOSAGE FORM
The intended purpose of this work is to develop and validate a dissolution test for betamethasone acetate and betamethasone sodium phosphate injectable suspension using a reverse-phase liquid chromatographic method. After testing sink conditions, dissolution medium and stability of the drug, the best conditions were: flow through cell of diameter 22.6 mm, 2.0 ml per minutes flow rate for 120 minut...
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