Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
QUANTUM AND HISTOLOGICAL STUDIES OF PARACETAMOL ALTERNATIVES TO AVOID CANCER EFFECT
Paracetamol (acetaminophen) (PA) is a widely used as an analgesic and antipyretic drug that is commonly available in without a prescription. Paracetamol has been used to treat many diseases such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers. It cures pain in mild arthritis but has no effect on the underlying inflammation and swelling of the joints. It has been repor...
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LYOPHILIZATION CYCLE COMPARISON AND SCALE-UP OF ESOMEPRAZOLE SODIUM FOR INJECTION BETWEEN LAB SCALE AND SCALE-UP BATCHES VS FDM STUDY
Lyophilization also known as freeze drying is a process in which water is removed from a product after it was frozen and placed under a vacuum, allowing the ice to change directly from solid to vapor without passing through a liquid phase. The process consists of three separate, unique, and interdependent processes; freezing, primary drying (sublimation), and secondary drying (desorption...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NEW PYRAZOLE DERIVATIVES
The synthesis of a novel of pyrazole derivatives was achieved by condensation of acetyl furan with phenyl hydrazine to give hydrazone (1) On the other hand, cyclization of α, β-unsaturated ketone. Using Vilsmeier reagent by DMF (dimethylformamid) and POCl3 Phosphorusoxychloride) to give compound (2). The chemical structures of allnew compounds were established by IR, ¹HNMR, and mass spectra dat...
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GABA-AT INHIBITORY ACTIVITY OF BENZOTHIAZOLE – GABA ANALOGS: IN-SILICO APPROACH FOR ANTIEPILEPTIC PROFILE
Estimation of binding affinity of receptor – ligand complex in docking study of small molecules plays an Important role in structure based drug development process. The γ-amino-butyric acid amino-transferase (GABA-AT) exhibits a catalytic role in regulating γ-amino -butyric acid (GABA) level in brain and responsible for many physiological and pathological changes. Here, in – silico study o...
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EVALUATION OF ANTICANCER EFFECT OF BRASSICA RAPA CHINENSIS LINN. USING IN VIVO MODEL
Aim: Dalton’s Lymphoma Ascites cells (DLA) are a cancer of the lymphocytes, a type of cell that forms part of the immune system. The present study aims to evaluate the anticancer effect of methanolic extract of bokchoy (Brassica rapa Chinensis leaves) using in vivo model in mice. Methods: The experimental mice were divided to 5 groups. The methanolic extract (800 mg/kg) and nanoparticles of meth...
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DYSMENORRHOEA: PREVALENCE, IMPACT AND KNOWLEDGE ASPECT OF TREATMENT IN FEMALES OF REPRODUCTIVE AGE IN TERTIARY CARE TEACHING HOSPITAL
Objectives: To describe the prevalence, severity, impact and treatment aspects of dysmenorrhoea in females of reproductive age group in tertiary care teaching hospital. Material and Methods: This was a questionnaire based survey type study. Detail information regarding demographic profile, menstrual history and dysmenorrhoea was analysed. Severity of dysmenorrhoea was evaluated by a Menstrua...
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SCREENING OF PHYTOCHEMICAL AND IN-VITRO ANTIOXIDANT PROPERTY OF A POLYHERBAL FORMULATION
Herbal plants produce a diverse range of bioactive molecules, making them a rich source of different types of medicines. Thus, a proper scientific evidence or assessment has become the criteria for acceptance of herbal health claims. As such developing a polyherbal formulation will definitely produce synergistic effect as needed comparable to standard drugs that are available in market all over th...
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ANTI OBESITY ACTIVITY AND BENEFICIAL EFFECTS OF METHANOLIC EXTRACT OF DESMOSTACHYA BIPINNATA IN HFD AND PROGESTERONE INDUCED OBESITY IN RATS AND MICE
Obesity is very serious and concerned problem these days. From the first human civilization, research is going to find the drugs to treat obesity and its complications. Despite availability of many drugs in market to treat obesity, no single drug is ideal for treating all sorts of problems caused by obesity. So the research is going on finding perfect drug. Prior going to evaluating drugs on hum...
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PHENYTOIN MONOTHERAPY IN EPILEPSY AND ITS EFFECT ON TSH
Long term administration of antiepileptic drugs has been found associated with development of hypothyroidism. But conflicting reports about effect on thyroid stimulating hormone (TSH) are available in literature and duration required to bring about this effect has also not been reported. Therefore, twenty five newly diagnosed adult patients with epilepsy were subjected to estimation of TSH before ...
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EFFECTS OF JUSSIAEA REPENS L ON SPERM DNA INTEGRITY IN MALE ALBINO RATS
Fertility control is an issue of global challenge. Researchers are trying to develop male herbal contraceptives from natural sources. Jussiaea repens L (JR) is such an herb which is reported to have non toxic antigonadal activity in male rats. The present study has designed to evaluate whether crude queous extract of JR affects the DNA integrity of spermatozoa and also to study whether its actions...
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