NEUROPROTECTIVE PROPERITY OF CENTELLA ASIATICA AGAINST PENTYLENE- TETRAZOLE INDUCED EPILEPSY IN RAT BRAIN WITH PARTICULAR REFERENCE TO LIPID METABOLISM
This study evaluated the anticonvulsant effect of different extracts of Centella asiatica (CA) with particular reference to lipid metabolism in different regions of rat brain. The rats were randomly divided into 4 groups having 6 in each group: i.e. Control group received saline, PTZ-induced epileptic group (60mg/kg b.w op/ 1 day), epileptic group pretreated with chloroform extract (CE),...
Lycopene, a non-provitamin a carotenoid, found in tomatoes, processed tomato products and other fruits, due to which red to pink coloration is observed. Among all the dietary carotenoids, lycopene is one of the most potent naturally and abundantly occurring antioxidant. Lycopene has unique structural features and chemical features which contribute to specific biological properties and pharmacologi...
Coconut oil is said to be healthiest oil on the earth because it is used not only diabetes but it is also used to reduce weight, risk of atherosclerosis, risk of cancer, prevents bacterial, viral and fungal infections, improves digestion and nutrient absorption etc. Diabetes is all about sugar, the sugar in our bodies known as blood sugar or blood glucose. There is one fat that diabetics can consu...
EFFECT OF CLASSICAL HERBO – MINERAL SIDDHA FORMULATION AGASTHIYAR KUZHAMBU FUMIGATION THERAPY ON SILAIPUN (VARICOSE ULCER) – A CASE STUDY
Siddha system is one of the ancient systems of medicine. In this system the herbals, metals, minerals and animal products has been used to prepare the medicines for treating various illness. Siddha medicines are divided into internal medicines and external medicines, in which Pugai maruthuvam (Fumigation therapy) is one of the external therapies. Agasthiyar Kuzhambu is one of the classical herbo m...
COMPARATIVE PHARMACOGNOSTIC STUDIES OF TWO GHANAIAN MEDICINAL PLANTS: SABA SENEGALENSIS AND SABA THOMPSONII
The study sought to describe the pharmacognostic features for identification and quality control of closely related species Saba senegalensis (A. DC.) Pichon and Saba thompsonii (A. Chev.) Pichon (Apocynaceae), useful medicinal plants against inflammation and its related diseases in Ghana and West Africa. Macro-morphological, qualitative and quantitative microscopic features as well as physicochem...
Oral films are a novel approach for the development of orally disintegrating dosage forms. They are thin, elegant in appearance and can be made into various sizes and shapes like rectangular or circular. The strips may be flexible or brittle, opaque or transparent. Oral films are made up of various hydrophilic and hydrophobic polymers to provide rapid disintegration on the tongue without the need ...
ANALGESIC ACTIVITY OF EXTRACTS OF EULOPHIA OCHREATA LINDL. AND ZINGIBER CASSUMUNAR ROXB. IN ANIMAL MODEL
The present study was designed to investigate Analgesic activity of Chloroform extract and isolate 1 of Eulophia ochreata Lindl. and dicholoromethanolic extract and isolate 2 of Zingiber cassumunar Roxb. The analgesic activity was assessed by using acetic acid induced writhing method and hot plate method. In acetic acid induced writhing method the extracts and isolates of both plants was administe...
DEVELOPMENT AND VALIDATION OF METHODS USING DERIVATIVE SPECTRO-PHOTOMETRY FOR DETERMINATION OF DIPYRONE IN PHARMACEUTICAL FORMULATIONS
Dipyrone (sodium noramidopyrine methanesulfate), a member of the pyrazolone group, is a drug that possesses analgesic, antipyretic, anti-inflammatory, and spasmolytic properties. Traditionally, iodimetric methods have been recommended for the quantitative determination of dipyrone in all its pharmaceutical forms. This work describes the development of zero order and fourth order (∆λ = 10) deriv...
A PHARMACIST BASED INTERVENTION TO IMPROVE THE CARE OF PATIENTS WITH HYPERTENSION AND DIABETES MELLITUS IN A PRIVATE INSTITUTION
The study was intended to evaluate the effectiveness of patient counselling in improving the quality of life (QOL) and knowledge, attitude and practices (KAP) of hypertensive and diabetic patients in a private educational institution. The study was conducted for a period of six months with the help of validated KAP and QOL questionnaire. Impact of patient counselling was studied by comparing the K...
HIGH PREVALENCE OF HOOKWORM INFECTION AND APPARENT ABSENCE OF ASCARIS LUMBRICOIDES: A CASE STUDY AT THE KOMFO ANOKYE TEACHING HOSPITAL IN GHANA
Background: Parasitic helminth infection is one of the major risk factors underlying the high rates of anaemia and malnutrition in many third world countries due to the poor socio-economic and environmental conditions of the people and these play a very significant role in their transmission. Method: 2000 stool specimens collected between May and October 2008 at the Komfo Anokye Teaching Hospit...