Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
GENERALIZED ARTIFICIAL NEURAL NETWORK MODELLING AND ITS APPLICATION IN PERFORMANCE PREDICTION OF SUSTAINED RELEASE MONOLITHIC TABLETS
Artificial Intelligence is the simulation of human intelligence. From delivering simple groceries to doorsteps to solving the toughest task in scientists’ lab, it is surrounding human life in all the means. So how can the Pharma industry be untouched in the case of AI?! Artificial Neural Network (ANN) is a type of AI used to solve non-linear problems and predict the output for given input parame...
852
324
TASTE MASKING, DESIGN AND EVALUATION OF ORAL DISPERSIBLE TABLET OF ANTICHOLINESTERASE AGENT
This study aimed to determine for taste masking & design of Oro dispersible tablet of an anticholinesterase agent (Donepezil HCl) to achieve the patient compliance. Oral dispersible tablet prepared by compression method. The Anticholinergic activity assure by evaluation, drug dissolution, stability testing and standardize the oral dispersible tablet. On the basis of the preformulating and form...
896
501
SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL QUINAZOLINE DERIVATIVES AS ACID PUMP ANTAGONISTS
Gastric acid hypersecretion is a major cause of gastric complications like hypergastrinemia, hyperhistaminemia and Zollinger-Ellison syndrome. Out of various drug treatments used, H2-receptor antagonists possess some limitations, such as the development of tolerance when used for a long period, having a short duration of action, and no complete inhibition of acid secretion in response to a meal. I...
814
403
SYNTHESIS, SPECTRAL CHARACTERIZATION, AND IN-VITRO ANTIOXIDANT ACTIVITY SCREENING OF SOME NOVEL 2-HYDROXY QUINOLINE DERIVATIVES
In an attempt of synthesizing some novel and potent antioxidant activity having compounds, here some novel quinoline derivatives are reported. Initially using Vilsemeir-Hack reagent method 7-methyl or 8-methyl substituted 2-cholro-3-formylquinolines (Ia, b) were prepared. Further 7-methyl or 8-methyl substituted 2-hydroxy quinoline-3-carbaldehyde (IIa, b) were synthesized by the reaction of compou...
845
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EXPLORATION OF ANTI-HYPERGLYCEMIC POTENTIAL OF HERBAL MIXTURE IN STREPTOZOTOCIN-INDUCED TYPE-II DIABETES IN RATS
Indigenous plants like Withania coagulans fruits. Alstonia scholaris bark and Aegle marmelose leaves have been used for diabetes management by traditional Indian people for a long time. The present study was carried out to investigate anti-hyperglycemic potential of an herbal mixture comprising of extracts of these three plants in streptozotocin-induced diabetes in Wistar rats and to focus on its ...
729
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ANTIOXIDANT POTENTIAL OF MARINE CRAB PORTUNUS PELAGICUS FROM GULF OF MANNAR, SOUTHEAST COAST
Natural products offer great hope in the identification of bioactive compounds and their development into drugs for the treatment of various diseases. The present study aims to evaluate the antioxidant potential of Portunus pelagicus. P. pelagicus (Station-I) possessed 33.14% of inhibition, the highest DPPH activity, whereas Station II and Station III showed 31.42% and 30.85% of inhibition. Portun...
802
348
APPLICATION OF PLACKETT–BURMAN DESIGN OF EXPERIMENTS IN THE IDENTIFICATION OF “MAIN FACTORS” IN THE FORMULATION OF DABIGATRAN ETEXILATE MESYLATE IMMEDIATE-RELEASE TABLETS
The current research paper was focused on exploiting Plackett-Burman design to screen the effect of eight factors Pregelatinised Starch (A), Crospovidone (B), Microcrystalline Cellulose PH 101 (C), Talc (D), Magnesium Stearate (E), Hydroxy Propyl Methyl Cellulose (F), Hydroxy Propyl Cellulose (G) and Lactose Monohydrate (H) on the release of drugs from the Immediate release DEM Cocrystal tablets p...
1064
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ENHANCEMENT OF SOLUBILITY OF POORLY SOLUBLE DRUG BY INCLUSION COMPLEXATION WITH γ-CYCLODEXTRIN
Candesartan is an angiotensin receptor blocker, used as an anti-hypertensive drug. It is available in the salt form of cilexetil i.e.; Candesartan cilexetil belongs to class II of the Biopharmaceutical classification system. It is a poorly soluble drug, and the bioavailability is 15%. The intention of the study is to improve the solubility of the poorly soluble drug, Candesartan cilexetil using th...
1893
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IN-VITRO AND IN-SILICO STUDIES ON SELECTED PHYTOCONSTITUENTS OF MITRAGYNA PARVIFOLIA (ROXB.) STEM BARK FOR ANTI-CANCER ACTIVITY
Cancer is a dreadful disease all over the world. The death rate had been increasing because of different types of cancers even though several drugs, treatment models and regimens are invented by scientists. Natural drugs have been showing remarkable results in the treatment of different cancers with less or no side effects. Advancements in screening methods using computer aided tools helping the r...
881
445
ISOLATION AND IDENTIFICATION OF STREPTOCOCCUS MUTANS FROM PATIENTS WITH DENTAL CARIES: EVALUATING THE ANTI-BACTERIAL EFFICACY OF THE AZADIRACHTA INDICA EXTRACTS FOR THE TREATMENT OF PERIODONTITIS
Periodontitis is a common infection occurring among a wide range of population globally. Streptococcus mutans is found to be the predominant pathogen responsible for dental caries. The present study concentrates on isolation and identification of the predominant pathogen from patients suffering from dental caries. The isolates were grown on various selective and differential media. Biochemical tes...
1948
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