In vitro antioxidant activity test was carried out on partially purification of methanol extract of Acorus calamus. Partially purification was done to obtain ten fractions. Partial purification was carried out by using hexane: ethyl acetate solvent system. These fractions were studied for the polyphenolics and antioxidant activity. S6 –S9 fractions shows maximum radical scavenging activity, ...
FIRST REPORT ON EVALUATION OF ANTI-DIABETIC POTENTIAL OF CHITIN AND CHITIN-BASED DERIVATIVES AGAINST ALLOXAN INDUCED ALBINO RATS
Crustacean’s shells constitute the traditional and current commercial source of Chitin. These derivatives/molecules are potential resource as well as multiple functional substrates have generate attractive interest in various fields such as biomedical, pharmaceutical, food and environmental industries. In the present investigation, chitinous wastes were collected from the fresh water areas of De...
Cancer is a global problem. However, in low-income and developing countries, the expenditures associated with its treatment are increasing disproportionately with resources available. Hence, reducing the drug wastage and financial burden placed on patients, family and society in general is becoming imperative. Our aim was to calculate therapeutic and economic benefits derived by the use of a centr...
EVALUATION OF CARDIOPROTECTIVE EFFECTS OF CAMELLIA SINENSIS ON ISOPROTERENOL INDUCED MYOCARDIAL INFARCTION
Background: Black tea is rich in polyphenols which are antioxidants. The most abundant polyphenolic compounds are flavonols and catechins. Black tea antioxidants showed protective actions against chronic diseases like cardiovascular diseases due to their antioxidant action. Objective: The present study was conducted to evaluate the cardioprotective effects of Camellia sinensis on isoproterenol ...
SYNTHESIS, ANTIBACTERIAL AND ANTI- MYCOBACTERIAL ACTIVITY OF SOME NOVEL3-(6-PHENYL-[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-3-YL)-2H-CHROMEN-2-ONE
Several 3, 6-substituted - [1,2,4] Triazolo [3,4-b][1,3,4] Thiadiazole}-2H-Chromen-2-ones(5a-5j) have been synthesized from ethyl-2-oxo-2H-chromene-3-carboxylate (1) through a multistep reaction sequence. Compound 1 reacted with hydrazine hydrate in the presence of ethanol to give 2-oxo-2H-chromene-3-carbohydrazide (2) which on treatment with carbon disulphide and methanolic potassium hydroxide ...
The aerial parts essential oils of Ocimum basilicum (Lamiaceae) from Togo were steam-distilled and investigated for their percentage composition (GC and GC/MS) and in vitro antimicrobial activities. Five oil chemotypes were identified and classified as follows in line with their principal components: estragole type; linalool/estragole type; methyleugenol type; methyleugenol/t-anethole type; taneth...
TREATMENT WITH GLIPTINS AND STUDY OF THE VARIATIONS IN SERUM AMYLASE AND SERUM LIPASE LEVELS IN TYPE 2 DIABETES MELLITUS
Objective: To observe the variations in levels of serum amylase and serum lipase, in patients with type 2 DM after treatment with DPP-4 inhibitors. METHODS: Under this study, 174 Type 2 diabetes mellitus patients were analysed for variations in levels of exocrine pancreatic enzymes after use of dipeptidyl peptidase (DPP) 4 inhibitors. The effect was compared with those under treatment with other o...
There are various drugs used in daily life. Some of them show hazardous effect on various organs and some of them shows even lethal effect. Such drugs are required to banned. One of them is Etizolam (marketed under the brand name Sedekopan, Pasaden or Depas) is a drug which is a thiebenzothiodiazepines analog. The aim of this work is done to compare the effect of administrati...
POSSIBLE RETRIEVAL OF ORGANOCHLORINE INDUCED RENAL TOXICITY IN FISH BY AQUEOUS ROOT EXTRACT OF WITHANIA SOMNIFERA: IN VIVO STUDY
The present study was aimed to assess the reno-protective impact of aqueous extract of root of Withania somnifera (WSR) commonly known as Ashwagandha against organochlorine induced renal toxicity in fish Clarias batrachus (Linn.).Fishes were exposed to 4ppb concentration of commercial brand Endocel, an organochlorine pesticide for one week and two week to prepare the toxic model. These toxic group...
PROTECTIVE EFFECT OF “RAPHANUS SATIVUS” EXTRACT AGAINST COPPER SULPHATE TOXICITY IN “CTENOPHARYNGODON IDELLA” FISH
The living organisms of the aquatic ecosystem have been directly affected by the accumulation of the heavy metals in the aquatic environment 1. Fishes are very good biosensors of aquatic contaminants and as bio-indicator species respond with great sensitivity to changes in the aquatic environment. Copper will accumulate in many different organs in fish and mollusks. In the present study the acute ...