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ENDODONTIC PAIN – CAUSE AND MANAGEMENT: A REVIEW
Pain is the most predominantly associated symptom with patients visit to the dental office. The pain may arise due to either an endodontic cause or a periodontic cause, but the endodontic pain type variant is the most commonly encountered by the dentists in their dental offices. Even though the endodontic pain is more common, there arises a dilemma in diagnosing and planning the treatment for the ...
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EFFECT OF LIGHT AND HEAT ON STABILITY OF CRUDE CAROTENOID EXTRACT FROM NATURAL SOURCES
Carotenoids are accessory coloring pigments found occurring naturally in the plants and some photosynthetic organisms. Recently there has been an increased focus on the health benefits and food applications of these natural pigments. The stability and bioavailability of carotenoids vary significantly across a range of processing paradigms. The present study was planned to investigate stability o...
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HERBAL REMEDIES FOR NEURODEGENERATIVE DISORDER (ALZHEIMER’S DISEASE): A REVIEW
Alzheimer’s disease, a neurodegenerative disorder is characterized by intense memory loss enough to interfere with social and occupational execution.It is the most general form of dementia, affecting more than 20 million people worldwide. The treatments of Alzheimer's disease are through cholinesterase inhibitors or NMDA-receptor antagonists, while doubts remain about the therapeutic efficacy of...
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MORPHOLOGY, PHYTOCHEMISTRY AND PHARMACOLOGY OF SYZYGIUM CUMINI (LINN.) – AN OVERVIEW
Syzygium cumini (L.) is a widely used medicinal plant for the treatment of various ailments. The plant contains anthocyanins, glucoside, ellagic acid, isoquercetin, kaempferol, and myricetin as its chief active constituents. These active cons isoquercetin, kaempferol tituents impart multiple pharmacological activities to the plant which includes antidiabetic, anticancer, antioxidant, antibacterial...
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RECENT NOVEL ADVANDCEMENTS IN PELLET FORMULATION: A REVIEW
Pelletization can be defined as an agglomeration process that converts fine powders or particles of a bulk drug and excipients into small, free-flowing, more or less spherical units, called pellets. The size of the pellets is 0.5-2mm. Pellets have the free flowing capacity and have low porosity about 10%. Preparation methods include direct pelletizing,powder layering,Suspension or Solution layerin...
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ANTI-OXIDANT AND ANTI-INFLAMMATORY ACTIVITY OF CUCUMIS SATIVAS (CUCUMBER) FLOWERS
Cucumis sativus (Cucumbers) have not received as much press as other vegetables in terms of health benefits, but this widely cultivated food provides us with a unique combination of nutrients. At the top of the phytonutrient list for cucumbers are its cucurbitacins, lignans, and flavonoids. These three types of phytonutrients found in cucumbers provide us with valuable antioxidant, anti-inflammato...
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FORMULATION AND EVALUATION OF LIPOSOMES OF FENOFIBRATE PREPARED BY THIN FILM HYDRATION TECHNIQUE
The objectives of the present study were to use design of experiments (DOE) for formulation and optimization liposomal formulations and study the impact of process variables on quality attributes of the complex liposomal formulation system. Several factors may have contributed to the slow pace of commercialization of liposome drug products during the last decade: 1) the difficulties associated wit...
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HPLC-ELSD DETERMINATION OF SODIUM LAURYL SULPHATE AND POLYSORBATE IN NEBIVOLOL DRUG PRODUCT AND DIFFERENT FORMULATION PRODUCTS
The contents of Sodium lauryl sulphate (SLS) and Polysorbate (Tween 80) were studied in different formulations of Nebivolol film coated tablets. The contents were extracted using the diluent Methanol: Water in the ratio 60:40 v/v and analyzed in HPLC coupled with Evaporative light scattering detector (ELSD). SLS and Tween 80 are solubilizing agents and the amount of these contents are critical in ...
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A REVIEW ON PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES OF PHYLLANTHUS AMARUS SCHUM. AND THONN.
Phyllanthus amarus Schum and Thonn herb is in traditional medicine for more than 3000 years. It belongs to a family of Euphorbiaceae and commonly known by the name of carry me seed, stone breaker, gala of wind, etc. It is a branching annual herb of 30 - 60 cm height widely spread throughout tropics and sub-tropics as a weed. Phyllanthus amarus is gaining momentum for its hepatoprotective, anti-car...
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MEDICATED CHEWING GUM – A 21st CENTURY DRUG DELIVERY SYSYTEM
In recent years scientific and technological advancements have been made in the research and development of oral drug delivery system. The reasons that the oral route achieved such popularity may be in part attributed to its ease of administration. Over the years, patient convenience and patient compliance-oriented research in the field of drug delivery has resulted in bringing out potential innov...
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