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USE OF LIPOSOMES IN CANCER THERAPY: A REVIEW
Cancer is uncontrolled growth of abnormal cells in the body. The cells causing cancer are called malignant cells. There are so many means by which one can treat the cancer such as chemotherapy, radiation treatment, surgery, etc. With all these treatments there are some side effects as loss of hairs, living cells may get killed, for surgery skilled persons are required and chances of reoccurrences ...
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TOPICAL LIPOSOMAL GEL: A REVIEW
Liposomes have been established as a promising novel drug delivery vehicle in several different basic sciences. Liposomes are microscopic spheres with an aqueous core surrounded by one or more outer shells consisting of lipids arranged in a bilayer configuration. Liposomes are acceptable superior carriers having ability to encapsulate hydrophilic and lipophilic drugs and protect them from degradat...
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A REVIEW ARTICLE ON CLEANING VALIDATION
Pharmaceutical product and active pharmaceutical ingredients (APIs) can be contaminated by other pharmaceutical products or APIs, by cleaning agents, by microorganisms or by other materials e.g. air borne particle, dust, lubricants, raw materials, intermediates. Mainly cleaning is performed to remove product and non-product contaminating material. Ineffective cleaning can lead to adulterated produ...
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BUCCAL PATCHES: A REVIEW
Buccal route is an attractive route of administration for systemic drug delivery and it leads direct access to the systemic circulation through the internal jugular vein bypasses drugs from the hepatic first pass metabolism provides high bioavailability. Buccalbioadhesive films, releasing topical drugs in the oral cavity at a slow and predetermined rate, provide distinct advantages over traditiona...
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ISOLATION, SCREENING AND CHARACTERIZATION OF L-ARGINASE PRODUCING SOIL BACTERIA
L-arginase (EC 3.5.3.1) is a therapeutic enzyme which catalyzes the hydrolysis of L-arginine to L-ornithine and urea. L-arginase is of keen interest due to its significance as an anti-cancer mediator against auxotrophic cancers. This enzyme is widely distributed and expressed in organisms like fungi, plants, non-chordates, and chordates, however very scarce report is available for L-arginase from ...
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A REVIEW ON ELECTROPHORESIS, CAPILLARY ELECTROPHORESIS AND HYPHENATIONS
Electrophoresis is an effective analytical tool for separation, as it does not affect the molecular structure, and it is also highly sensitive to small differences in molecular charge and size of the analytes. Capillary electro-phoresis is a separation technique where the ions are separated based on their electrophoretic mobility with an applied voltage. So far, the research field of capillary ele...
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A REVIEW ON PHYTOCHEMICAL AND PHARMACOLOGICAL RESEARCH – REMEDY FOR SICKLE CELL DISEASE
Aim: This article focuses on the current review of world-wide medicinal plants studied for their phytochemical investigations, various biological activities and clinical studies in relation to their use for treatment of Sickle cell disease. Method: All relevant literature databases were searched up to 18 September 2014. The search terms were plant, herb, herbal therapy, phytotherapy, sickle cell a...
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PONGAMIA PINNATA: AN OVERVIEW
The word herb, as used in herbal medicine, is also known as botanical medicine or as Phytotherapy or Phytomedicine which means a plant or plant part is used to make medicine to assist in the healing process during illness and disease. So there are many herbal remedies individually or in combination have been recommended in various medicinal treatises for the cure of different diseases. It contains...
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IRANIAN MEDICINAL PLANTS EFFECTIVE ON SEXUAL DISORDERS: A SYSTEMATIC REVIEW
Medicinal plants used in traditional medicine and various cultures can be valuable resources for discovering new drugs. This review was conducted to report Iranian medicinal plants effective on sexual dysfunction (sexual desire disorders, erectile dysfunction, and premature ejaculation). To conduct this systematic review, the search terms Sexual*, Aphrodisiacs, Erectile, and Libido* combined with ...
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VARIOUS ANIMAL MODELS FOR PRECLINICAL TESTING OF ANTI-INFLAMMATORY AGENTS
Inflammation is the local defensive response of living tissues to injury or due to any other chemical agents. Inflammation consists of two basic processes early inflammatory response later followed by healing. There are two types of inflammation, acute and chronic. The different animal models (i.e. vascular permeability, UV-erythema in guinea pigs, Croton-oil ear edema in rats and mice, Paw edema ...
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