Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
IN VITRO AND IN VIVO EVALUATION OF ACECLOFENAC LYOPHILIZED ORALLY DISINTEGRATING TABLETS
Aceclofenac, a non-steroidal anti- inflammatory drug, with poor solubility and bioavailability was taken as candidate for enhancement of in vitro dissolution and in vivo bioavailability. Development of Aceclofenac orally disintegrating tablet (ODT) using lyophilization technique was adopted. The ODTs were prepared by freeze-drying an aqueous dispersion of Aceclofenac, matrix former, filler (sugar ...
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1926
ANTIMICROBIAL ACTIVITY OF SOME MEDICINAL HERBAL EXTRACTS ON CLINICALLY IMPORTANT BACTERIAL PATHOGENS
The antibacterial activity of methanol extract of Abutilon indicum, Hygrophila spinosa and Mimosa pudica were studied by agar well diffusion method in vitro. The effect of antibacterial potential was examined against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus, Proteus vulgaris, Enterococcus faecalis, Klebsiella pneumoniae, Vibrio cholerae, Salmonella typhi a...
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1678
PURIFICATION AND CHARACTERIZATION OF RIBOFLAVIN BINDING PROTEIN FROM THE EGG WHITE OF EAGLE (AQUILA HASTATE)
Riboflavin binding protein (RfBP) was isolated from the eggs of Aquila hastate (eagle). The protein was purified in two steps, DEAE – Sepharose ion exchange chromatography and gelfilteration on Sephadex G-100. The holoprotein had an absorption spectrum characteristic of flavoproteins. The purity of the protein was judged by SDS-PAGE technique. A single band on the slab and cylindrical gel reveal...
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1561
COMPARISON OF BLUMEA DENSIFLORA AND SALVINIA CUCULLATA LEAVES FOR THEIR ANTHELMENTIC ACTIVITY BY USING PHERETIMA POSTHUMA
Plant derived drug molecules are frequently showing their role in treating the disease conditions with minimal side effects comparing to the synthetic molecules. Forest and trees are natural assets that provide a variety of benefits to the mankind. Currently available anthelmintic drugs require improved management, high cost and also worms developing resistance to these drugs. So, there is a need ...
4204
1693
SCREENING OF BANGLADESHI VEGETABLES FOR PEROXIDASE
Various locally available vegetables were screened for the enzyme peroxidase. The screening was performed mainly on daikon, cabbage, cauliflower; tomato and sweet potato etc. The juices of these vegetables were extracted and subjected to ammonium sulphate precipitation followed by dialysis to remove any adhere salts. The partially purified enzymes were then subjected to peroxidase assay. All the e...
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2775
FORMULATION AND EVALUATION OF ALCOHOL RESISTANT DOSAGE FORMS OF GLIPIZIDE
Oral controlled release pellet formulations of glipizide were prepared using extrusion spheronization technique. Pellets provide specific advantages in controlling the drug release and increasing the absorption of the active ingredient. The major drawback for these systems is dose dumping which is very prominent in presence of alcohol. In the present study, attempt was made to prepare alcohol resi...
4046
1747
EXCITOTOXICITY AND CELL DAMAGE – A REVIEW
Excitotoxicity refers to the pathological process by which nerve cells are damaged & killed by glutamate or related excitatory amino acid under conditions such as after intense exposure. This occurs when receptor for the excitatory neurotransmitter such as N-methyl-D-aspartate (NMDA) or AMPA are over activated. Such excitotoxic neuronal death may take part in the pathogenesis of brain or spina...
5183
1860
THE ANTIMICROBIAL ACTIVITY OF n-C6H14 AND CH3CH2OH EXTRACT OF SOLANUM MELONGENA FRUIT AND LEAVES OF MORINGA OLEIFERA
As part of a research initiative to evaluate plants used for their nutritional and herbal values, the antimicrobial activity of Solanum Melongena’s fruit and Moringa oleifera’s leaveswere investigated. Each plant part was subjected to selective extraction using solvents of varying polarity: n-C6H14, CH2Cl2, EtOAc and CH3CH2OH. The n-C6H14 and CH3CH2OH extract of these two plants were tested fo...
4209
1755
SYNTHESIS, CHARACTERIZATION, DNA-BINDING, PHOTOCLEAVAGE AND ANTI-MICROBIAL STUDIES OF COMPLEX [Ru(4-ETHYL- PYRIDINE)4(DPPZ)]2+
The new Ru (II) complex [Ru(4-Et-py)4(dppz)]2+ (dppz = dipyrido phenazine) have been synthesized and characterized by different analytical techniques like elemental analysis, LC-MS, 1H NMR , 13C NMR. The interaction of this complex with calf thymus DNA has been explored by U.V. absorption spectroscopy, Fluorescence measurements, and viscosity measurements. Their photocleavage behavior towards ...
3646
1693
EVALUATION OF ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF SYNTHESIZED AGENTS USING UGI MULTICOMPONENT REACTION
In the present study, analgesic and anti-inflammatory activities of the synthesized agents derived from Ugi four component reactions (Ugi-4CR) has been described. The synthesized novel Ugi derivatives 7 (a-h) were characterized on the basis of I.R, 1H NMR and mass spectral analysis. Healthy Wistar Albino rats were used to carry out these activities. Analgesic activity was evaluated by Eddy hot pla...
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