Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
A STUDY COMPARING RESCUE MEDICATIONS: ARFORMOTEROL AND SALBUTAMOL NEBULIZATION IN EXACERBATION OF NON-SEVERE ASTHMA AT A TERTIARY CARE CENTER, NOT NEEDING HOSPITALIZATION
Objectives: Arformoterol is the (R, R) - enantiomer of formoterol, a short and long acting β-2 agonist bronchodilator and is distinguishable from the racemic (R, R/S,S) - diasteriomer of formoterol, which is most commonly used. Some in vitro data show significant bronchodilatation, inhibition of inflammation and marked baseline airway reversibility with arformoterol. Yet, there is a dearth of stu...
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A NEW POLARIMETERIC METHOD FOR THE ANALYSIS OF SUCROSE – IN IRON SUCROSE RAW MATERIAL, IRON SUCROSE INJECTION AND INPROCESS BULK FORMULATIONS
A simple, sensitive, rapid, accurate and economical polarimeteric method has been developed and subsequently validated for simultaneous determination of Sucrose - in Iron Sucrose Raw material, Iron Sucrose Injection and Inprocess Bulk sample of Iron Sucrose formulations in pharmaceuticals. The usual measure of purity of sucrose is by polarimetry - the measurement of the rotation of plane-polarized...
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FORMULATION AND DEVELOPMENT OF LIPOSOMAL DELIVERY OF ANTICELLULITE
Aim: Cellulite treatment incorporates iso-slim complex to reload the skin with minerals and trace elements to achieve absolute effectiveness in treating cellulite condition. The revitalizing effect of anticellulite helps to refine and reshape the silhouette and give the body a more toned, defined and firmer appearance. Aim of present work was to develop and investigat...
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SYNTHESIS AND BIOLOGICAL ASSESMENT OF QUINAZOLONE BASED AMIDE LINKAGE CONTAINING THIAZOLIDINONE AND THEIR DERIVATIVES
A number of substituted quinazolones are well known for their pharmacological activities like anti-inflammatory, antibacterial and analgesic etc. The present work deals with synthesis of quinazolone based thiazolidinone in order to enhance the biological properties. A Series of (2-(substituted phenyl)-4-oxothiazolidin-3-yl) -4- (4-oxo-2-phenyl quinazolin-3(4H)-yl) benzamide (6a-6h) were synthesi...
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SPREADING OUT OF ACECLOFENAC SUSTAINED RELEASE MICROCAPSULES BASED ON HPMC 50 CPS BY EMULSION SOLVENT EVAPORATION TECHNIQUE
Sustained released Aceclofenac microcapsules based on synthetic hydrophilic polymer hydroxypropyl methylcellulose (HPMC) were developed in this study in an attempt to design a dosage form that would manifest desirable release profile. W/O emulsion solvent evaporation technique was employed. Various release retarding agents were used to provide the analgesic and anti-inflammatory action of aceclof...
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PRECLINICAL EFFICACY AND SAFETY OF HERBAL FORMULATION FOR MANAGEMENT OF WOUNDS
Background: Medicinal plants in Tripathi hills and other developing countries have been scientifically demonstrated to have medicinal benefits but few or none have been translated to products for clinical use. Most herbal products developed by local herbalist and sold to the public are not standardized and lack efficacy and safety data to support use. Objective: to evaluate the medicinal plants...
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ROLE OF ACUTE PHASE PROTEINS STATUS IN CHRONIC ALCOHOLIC LIVER DISEASES
Back ground: Alcoholic cirrhosis is a condition of irreversible liver disease due to the chronic inflammatory and toxic effects of ethanol on the liver. Acute alcoholic hepatitis occurs in habitual drinkers, often a period of increased alcohol intake. Although, the clinical features may mimic acute viral hepatitis. Progression of liver fibrosis to cirrhosis is dangerous as well as potentially life...
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AMPLIFICATION AND SEQUENCING OF MITOCHONDRIAL DNA (HVR-I) EXTRACTED FROM 1200 YEARS OLD HUMAN BONE SPECIMEN
Ancient DNA help in better understanding the evolution and migration pattern of humans throughout the world. The present work is a preliminary effort, to extract and amplify the ancient DNA from human bone samples provided by the Anthropological survey of India collected from the Himalayan region in 1952. Many technical difficulties arise during DNA extraction, PCR amplification and sequencing w...
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LIQUID CHROMATOGRAPHIC SEPARATION AND ANALYSIS OF TELMISARTAN AND HYDROCHLOROTHIAZIDE IN PHARMACEUTICAL FORMULATIONS
An accurate, simple and precise RP-HPLC method for the simultaneous determination of telmisartan and hydrochlorothiazide in pharmaceutical formulations was developed and validated. Chromatographic separation of two drugs was achieved on a Kromasil C18, (250x4.6nm, 5µm) column by using the mobile phase consisted of methanol, tetrahydrofuran and water in the ratio 55:05:40 at a flow rate of 1mL/min...
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HERB-DRUG INTERACTION: AN OVERVIEW
Plants have always provided an important source of medicines. They may be used by natives in folk medicine and later adopted by conventional western medicine as their efficacy was confirmed. Any pharmacological modification caused by herbal substances to another prescription medication (diagnostic, therapeutic or other action of a drug) in or on the body. An herb might increases or decreases the e...
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