Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
CHITOSAN-BASED INTRATUMORAL INJECTABLE NANOPARTICLES FOR GENE DELIVERY TO PANCREATIC CANCER CELLS
One of the obstacles to effective intratumoral gene delivery lies in low transfection efficiency of non-viral vectors. Thus, in this study we evaluate the application of Diethyl methyl chitosan (DEMC) in intratumoral gene delivery of pancreatic cancer. DEMC/ pEGFP nanoparticles are prepared by polyelectrolyte complexation. After nanoparticle characterization via atomic force microscopy (AFM), in i...
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CHARACTERISATION OF FLAVONOID GLYCOSIDES IN PHARMACOPOEIAL PREPARATION OF CISSUS VERTICILLATA (L) NICOLSON & C. E. JARVIS) USING HPLC-DAD AND HPLC-MS
According to Brazilian regulation, the registration of phytomedicines must inform the characterisation of, at least, one of their constituent. In order to contribute to this goal, a tincture of Cissus verticillata (L.) Nicolson & C.E. Jarvis prepared with ethanol 96oGL was investigated. This plant species is widely used due its hypoglycaemic properties, to control diabetes, and empirically to ...
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FORMULATION AND IN VIVO EVALUATION OF VETERINARY CHLORPROMAZINE SOLUTIONS FOR INTRAMUSCULAR INJECTION
The purpose of the study was to present the know-how of preparing intramuscular injection forms of chlorpromazine HCl (CPZ) solutions for use in veterinary medicine. Aqueous solutions of CPZ were prepared aseptically at concentrations of 10 or 25 mg/ml. The CPZ formulations were intended for veterinary use only. The concentrations of CPZ in the solutions were 1 or 2.5% which were formulated main...
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EVALUATION OF HAEMATINIC ACTIVITY OF POLYHERBAL FORMULATION IN HgCl2 INDUCED ANAEMIA IN LABORATORY ANIMALS
Anaemia constitutes serious health problem in many countries. It is widespread public health problem, and the fourth leading cause of hospital admissions and the second factor contributing to death. Anaemia is characterized by low count of haemoglobin. The empirical use of herbal preparations in the treatment of anaemia dates from ancient times. Despite the obvious effectiveness and efficacy of ir...
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FORMULATION OF REGIOSELECTIVE FLOATING MATRIX TABLETS OF DEXTRO-METHORPHAN USING GAS FORMING TECHNIQUE AND EVALUATION
The present study deals with the formulation and evaluation of gastroretentive floating tablets of dextromethorphan. Dextromethorphan is a highly potent and commonly used antitussive agent. It has no narcotic, analgesic or addictive properties and its potency as an antitussive agent is almost equal to that of codeine. The purpose of this research is to increase the gastric residence time by prepar...
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IN-SILICO ANALYSIS AND HOMOLOGY MODELING OF ANTIOXIDANT PROTEINS OF ORYZA SATIVA SUBSP. JAPONICA (RICE)
Rice is much revered oriental food and the most important tropical cereal crop. It is the staple food of about half the human race and is often the main source of calories and the principal food of many millions of people. Health benefits of rice include providing fast and instant energy, stabilizing blood sugar levels and providing essential source of vitamin B1 to human body. In this study...
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EFFECT OF XYLIA DOLABRIFORMIS LEAVES EXTRACT ON HIGH FRUCTOSE DIET INDUCED C57BL/6J OB/OB DIABETIC MICE
The objective of the present study was to investigate anti-diabetic and nephroprotective and cardioprotective activity of Xylia dolabriformis leaves extract, using High Fructoseinduced diabetic C57BL/6Job/ob mice as model for clinical type-2 diabetic. At a regular interval of an experimental protocol blood glucose, urinary creatinine, total proteins, insulin resistance, total β-cell count, LDL, H...
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PHARMACOGNOSTICAL EVALUATION OF BOMBAX MALABARICUM LEAVES
In different parts of India, Bombax malabaricum (Family: Bombacaceae), is well known for its traditional use in inflammation, prolapse of uterus or vagina, menorrhoea, diarrhoea, wound etc. Literature survey showed that the leaves of Bombax malabaricum have anti-inflammatory, antipyretic, analgesic and antioxidant activities. Although the plant has much potentiality, proper pharmacognostical stand...
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COMPARATIVE IN VITRO DRUG RELEASE STUDIES OF GLIMEPIRIDE SOLID DISPERSIONS & METFORMIN MICROCAPSULES
The study was undertaken to compare the efficacy and safety of Glimepiride and Metformin in the management of patients with type 2 DM. The present invention is directed to a pharmaceutical composition in the form of a capsule with increased bioavailability as well as the process for obtaining said composition. The tablet of the present invention comprises two active ingredients comprising two oral...
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POSTNATAL DEVELOPMENT OF STOMACH IN SWISS MICE INDUCED BY LEAD ACETATE
Histopathological changes in developing stomach caused by lead acetate exposure at different days of the postnatal development were investigated in Swiss mice. In this study, pregnant Swiss mice were exposed to 533 mg/kg BW of lead acetate from 10th day of gestation to 21st day of lactation. The pups of exposed groups were sacrificed at 1, 7, 14 and 21 day of lactation period, and the effects of l...
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