Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
EFFECTS OF ALOE VERA ON LIVER OF SWISS ALBINO MICE AGAINST SUBLETHAL DOSE OF GAMMA RADIATION
The radioprotective effect of Aloe vera was studied in liver of Swiss albino mice. Animals were divided into three groups. Animals of group I administered double distilled water only, group-II Aloe vera (drug) and control set of group III were given radiation only where as animals experimental set of group III were administered by Aloe vera + Radiation. Animals were given Aloe vera leaf extract or...
4210
2524
FORMULATION OF DIRECT COMPRESSED VERAMPAMIL SUSTAINED RELEASE FORMULATION USING OPTIMIZED CO PROCESSED EXCIPIENTS
Pharmaceutical excipients when co-processed have improved flow and disintegrant properties in tablet formulations. However, physical mixtures of excipients show limited functions, poor flow properties, and poor functional properties so they cannot be used directly in tablet formulations. Majority of solid dosage forms contain multiple excipients, which provides a wide window of opportunities by co...
4285
1987
MODULATORY ROLE OF WITHENIA SOMNIFERA ROOT EXTRACT MIXED PELLETED FEED ON PESTICIDE INDUCED HEPATIC ANOMALIES’ IN FRESH WATER CATFISH CLARIAS BATRACHUS (LINN.)
The pharmacological activity of Withenia somnifera commonly called Ashwagandha, a herb having multi-medicinal properties, was investigated against carbofuran exposed hepatic anomalies in the air breathing fish Clarias batrachus. Fishes were exposed to 1 mg/L carbofuran for three weeks to induce the toxic effects. These fishes were then fed with Withenia somnifera root extract mixed pelleted fe...
4980
1745
BRASSICA OLERACEA: A POTENT ANTIOXIDANT THERAPEUTIC IN HEALTH AND DISEASES
Oxidative stress contributes towards initiation and progression of hepatic damage in a variety of liver disorders (e.g. Hepatitis C, Hepatitis B, non alcoholic fatty liver disease amongst others). Hence, there is a great demand for the development of agents with potent antioxidant effect. There are various plant derived products which act as antioxidants. The aim of the present investigation is to...
4132
1666
EVALUATING HYPOGLYCEMIC POTENTIAL OF KASNI (CICHORIUM INTYBUS) SEED PREPARATIONS IN TYPE 2 DIABETES MELLITUS PATIENTS
Objective: To evaluate hypoglycemic responses of Kasni (Cichorium intybus) seed preparations in combination with oral hypoglycemic agent in treatment of patients of newly diagnosed type2DM. Methods: Newly diagnosed 90 patients of type2DM, age 35-65years, of either sex were divided into 3 groups. Each group had 30 patients (19 male and 11 females) matched with each other in terms of age and sex. In...
5249
1753
ANTIHYPERGLYCEMIC ACTIVITY OF DIPTERACANTHUS PROSTRATUS NEES. AND ITS PROBABLE MECHNISM OF ACTION IN STREPTOZOTOCIN INDUCED DIABETIC RATS
The present study was aimed to investigate the antihyperglycemic effect of the Dipteracanthus prostratus nees. And it’s probable mechanism of action in Streptozotocin induced diabetes. Wistar albino rats were used to evaluate the antihyperglycemic effect of toluene (TEDP, 100 mg/kg and 200 mg/kg, body weight) and methanolic (MEDP, 100 mg/kg and 200 mg/kg, body weight) extract of D. prostratus. C...
4261
1577
A STUDY ON DRUG DOSE ADMINISTRATION IN GERIATRICS WITH RESPECT TO CREATININE CLEARANCE RATE
Objective: The objectives are to assess the drug dose administration and reduce the dose toxicity in geriatric patients. Method: A Prospective interventional study has been carried out on drug dose administration in geriatric patients with respect to creatinine clearance rate at a tertiary care hospital for about 6 months. A total number of 204(47 baseline+157study) geriatric patients are included...
5153
1838
ANALYTICAL METHOD VALIDATION FOR DETERMINATION OF RELATED SUBSTANCES OF DEXMEDETOMIDINE (IMPURITY-1) IN DEXMEDETOMIDINE HYDROCHLORIDE INJECTION
Dexmedetomidine, approved by the Food and Drug Administration (FDA) in 1999 as a sedative for use in the intensive care unit, is a potent and highly selective α2-adrenoceptor agonist with significant sedative, analgesic and anxiolytic effects mostly used in the intensive care units. This article describes validation for determination of related substances of dexmedetomidine (impurity-1) in dexmed...
9865
4678
ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF CANDESARTAN CILEXETIL IN BULK AND PHARMACEUTICAL DOSAGE FORMS BY THIRD ORDER DERIVATIVE SPECTROSCOPIC TECHNIQUE
Candesartan cilexetil, a prodrug is a racemic mixture containing one chiral center at the cyclohexyloxy-carbonyloxy- ethyl ester group. It is soluble in dimethyl formamide, acetone, methanol, 0.1 N sodium hydroxide solution and insoluble in water. Objective of the present study is to develop a simple, sensitive, accurate, precise and rapid derivative spectrophotometric method for the estimation of...
4941
1862
SYNTHESIS OF HETEROCYCLIC NITROGEN COMPOUNDS BY CLOSURE REACTIONS USING TETRAACETYLETHANE WITH VARIOUS PRIMARY AMINES
This work includes synthesis of new five, six, and seven-heterocyclic nitrogen compounds by closure reactions of tetraacetylethane (3) with primary amines in refluxing ethanol and acetonitrile as solvents and without using any catalysts. The tetraacetylethane melting point 184-189 ºC was prepared by condensation of two anhydrous molecules of sodium salt of acetylacetone and in the presence of dry...
5948
2342