Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SYNTHESIS AND CHARACTERIZATION OF NOVEL CHOLESTERYL LACTATE BASED FATTY ACID ANALOGS AND THEIR IN VITRO ANTIMICROBIAL ACTIVITY
A series of novel cholesteryl lactate-fatty acid conjugates (4a-i) were prepared by esterification of cholesterol with lactic acid, followed by coupling hydroxyl group of cholesteryl lactate with –COOH group of fatty acids including, saturated fatty acids of varying carbon chain of C10-C18, unsaturated fatty acids like 10-undecenoic, oleic ((9Z)-octadec-9-enoic), ricinoleic ((9Z,12R)-12-hydroxyo...
4411
1770
DOSE OPTIMIZATION OF CEFTRIAXONE-SULBACTAM COMBINATION IN PEDIATRIC USING IN-VITRO SYSTEMS AND STOCHASTIC SIMULATIONS APPROACHES
Increase in complexity and cost associated with pediatric safety and efficacy studies have reduced the interest of pharmaceutical companies to study bio-therapeutics in pediatric population. Dose recommendations are being made as per patient body weight or body surface area, with the assumption of linearity in body size dose adjustments. In the present study, newer approach i.e. flat fixed age-bas...
17895
2390
A NOVEL ASSAY METHOD OF 1-DEOXY NOJIRIMYCINE (DNJ) BY ION CHROMATOGRAPHY
A novel Assay method for the determinationof1-Deoxy nojirimycine(DNJ) was proposed by the authors using ion chromatography. The method was found to be accurate, simple and precise. A method precision RSD of 0.5%, RSD for intermediate precision of 0.6% and correlation coefficient was found to be 0.9999. A recovery of 99.7 to 100.1% at 50%, 100% and 150% levels was found. The DNJ solutions and mobil...
5771
2937
SYNTHESIS, CHARACTERIZATION, AND PHARMACOLOGICAL EVALUATION OF SOME NOVEL HYDRAZONE DERIVATIVES DERIVED FROM 3-((4-FORMYL-2-METHOXYPHENOXY) METHYL) BENZONITRILE
Hydrazones are an important classe of biologically active compounds found in many synthetic compounds. In view of their importance in synthetic chemistry, the present article reported that a new series of novel hydrazone derivatives (4a-e) were synthesized by condensation of 3-((4-formyl-2-methoxyphenoxy)methyl)benzonitrile(3) with different benzohydrazides and confirmed by their IR, 1H NMR, and M...
4806
2378
FORMULATION, OPTIMIZATION & EVALUATION OF SOLID DISPERSION BASED GASTRORETENTIVE FLOATING TABLETS OF CEFPODOXIME PROXETIL
The objective of present study was to preclude of poor dissolution of relatively water insoluble and poorly permeable drug by formulating gastroretentive floating tablet using solid dispersion (SD) of the drug. It aimed to increase the drug solubility and gastric retention of the drug for better absorption profile. Cefpodoxime proxetil is an orally absorbed third generation cephalosporin antibioti...
5574
1926
EVALUATION OF NS1 ANTIGEN-CAPTURE ELISA AND IgM ANTIBODY CAPTURE ELISA IN ACUTE CASES OF DENGUE IN RURAL POPULATION IN A TERTIARY CARE TEACHING HOSPITAL IN WESTERN UTTAR PRADESH INDIA
Background: Dengue is a major public health problem in resource-limited countries like India. There has always been a quest for best serological test for prompt and accurate diagnosis and whether single test or a combination be used. Enzyme immunoassays based on the detection of dengue virus non-structural protein 1 (NS1), and IgM antibody capture are available with different sensitivities and spe...
5158
1792
A COMPARATIVE STUDY OF EFFICACY AND SAFETY OF ORAL DICLOFENAC AND DECREASED DOSE OF DICLOFENAC PLUS TOPICAL DICLOFENAC IN TREATMENT OF KNEE OSTEOARTHRITIS
Objectives: To compare efficacy and safety of topical plus reduced dose of diclofenac to oral diclofenac in therapeutic dose. Method: The study was prospective, comparative and randomized, which included 50 patients suffering from knee osteoarthritis. Patients were randomized to receive either - oral diclofenac alone (50 mg thrice daily) (therapy1) or decreased dose of oral diclofenac and topi...
5637
1895
SUICIDE RISKS AMONG ADOLESCENTS: A LOOK BEHIND THE BLACK CURTAIN
This review article investigates the prevalent existence of suicide along with its risk factors and contributing factors leading to the culmination of them all, in an attempt to look behind the black curtain. Suicide is the result of an unbalanced scale between the good and bad. Every year 300,000 teenagers attempt and succeed at suicide worldwide. A set of emotions and unpleasant thoughts develop...
9071
2218
EVALUATION OF PHYTOCHEMICALS AND IN VITRO PHARMACOLOGICAL ACTIVITY OF ACACIA SINUATA PLANT LEAVES
Objective: The present work is aimed to screen phytochemicals, in vitro antimicrobial and antioxidant activity of the non polar and polar extracts of Acacia sinuata. Methods: Leaves of Acacia sinuata- were collected, dried and powdered. The powdered material is subjected to soxhlet extraction using various polar to non polar solvents and allowed for evaporation. The crude extracts thus obtained we...
6499
2523
STUDY OF VARIATION IN PRICE OF VARIOUS NSAIDS COMBINATIONS AVAILABLE IN INDIAN MARKET
Introduction: Non Steroidal Anti Inflammatory drugs are widely used drugs worldwide for various inflammatory conditions and acute as well as chronic pain conditions. In India large number of NSAIDs preparations are available in the market. Therefore choosing a NSAID becomes very difficult task for the prescribing physician. Objective: To evaluate the price variation of the different NSAIDs prepara...
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