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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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30.

ASSESSMENT OF PRIMARY HEALTH CARE WORKERS’ KNOWLEDGE, ATTITUDES AND PRACTICES ON UNCOMPLICATED MALARIA MANAGEMENT IN PLATEAU STATE, NIGERIA

Overcoming the scourge of malaria infection is possible when healthcare workers have good levels of understanding and attitudes towards the disease, which will influence their treatment practices. This study assessed healthcare workers’ levels of knowledge, attitudes, and practices (KAP) in uncomplicated malaria treatment at primary healthcare (PHC) facilities in Plateau state, Nigeria. The stud...

N. E. Ismail *, N. S. Jimam and M. L. P. Dapar

Department of Clinical Pharmacy, Faculty of Pharmacy, MAHSA University, Selangor, Malaysia.

DOI: 10.13040/IJPSR.0975-8232.10(1).286-93

286-293

3964

1585

48.

FLAVONOIDS OF BOERHAVIA DIFFUSA – GC-MS ANALYSIS AND INHIBITORY ACTIVITY AGAINST PATHOGENIC MICROBES

Boerhavia diffusa is a species of flowering plant in the four o'clock family, Boerhavia belongs to family Nyctaginaceae the plant holds the tremendous potential of medicinal value and has been traditionally used in various ailments like syphilis, leukoderma, blood disorders to name a few. The present study focuses on the GC-MS analysis of extracts of all the plant parts of B. diffusa which reveal...

R. Bhardwaj * and R. A. Sharma

Department of Botany, The IIS University, Jaipur, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.10(8).3905-14

3905-3914

3964

1850

33.

IMMOBILIZATION OF TANNIN ACYL HYDROLASE FROM ASPERGILLUS NIGER

Tannin acyl hydrolase, commonly referred to as tannase (E.C. 3.1.1.20), an inducible extra-cellular enzyme produced by a number of animals, plants and microbes. In this investigation, tannase production under solid-state fermentation by using Aspergillus niger and the waste residue of cashew husk was used as substrate for obtaining the desired fermented product. After termination of fermentation g...

B. Lenin Kumar*, N. Lokeswari and D. Sriramireddy

Research Scholar, Department of Biotechnology, Dr. B.R. Ambedkar University, Etcherla, Srikakulam Dist., Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(4).1485-87

1485-1487

3963

1606

36.

ANTIDIABETIC ACTIVITY OF METHANOLIC EXTRACT OF BARK OF BAUHINIA PURPUREA

The present investigation was carried out to study the antidiabetic effect of the methanolic extract of bark of Bauhinia purpurea in Streptozotocin induced diabetic model. The antidiabetic activitywas evaluated in normal & Streptozotocin induced diabetic rats. Decreased blood glucose level of the test animals showed that the extract exhibited significant antidiabetic activity when compared to ...

S. Pahwa*, R. Mazumder and S. Bhattacharya

A-227, Sarita Vihar, New Delhi, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(5).1444-47

1444-1447

3962

1771

44.

STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR DETERMINATION OF PROCESS IMPURITIES AND DEGRADATION PRODUCTS OF LEVOLEUCOVORIN CALCIUM FOR INJECTION

Levoleucovorin calcium contains amide and aldehyde groups which makes it vulnerable to degradation. Stability indicating method for determination of all seven process-related impurities and degradation impurities in Fusilev® 50 mg/mL injection was developed with the help of RP-HPLC. A Forced degradation study supports method development to ensure stability indicating conditions. Solutions of the ...

V. N. Patel, P. H. Sukharamwala and M. Mathur *

Department of Pharmaceutics, Faculty of Pharmaceutical Sciences, PES University, HN Campus, Bengaluru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.12(5).2892-01

2892-2901

3962

3224

24.

ANOVULATORY FOLLICLE DEVELOPMENT IN ADULT ALBINO MICE DUE TO PROLONGED EXPOSURES TO GENISTEIN

Genistein is a soy phytoestrogen that mediates its functions by interacting with the endogenous estrogen receptor β. To investigate the effect of 10mg/kg body weight/ day genistein administration up to 90 days on the ovarian folliculogenesis and its correlation with serum gonadotropins and estrogen, adult Mus musculus were either administered with 1:4 DMSO : PBS (vehicle) or with 10mg genistein/k...

S. Banik, A. D. Banik * and V. K. Shrivastava

Laboratory of Endocrinology Department of Bioscience Barkatullah University, Bhopal, Madhya Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.5(9).3752-57

3752-3757

3961

1693

39.

APPLICATION OF ELECTRON DENSITY AND MOLAR VOLUME AS DESCRIPTORS IN QSAR STUDY OF THE ANTIOXIDANT ACTIVITY OF FLAVONOIDS

QSAR study of lipid peroxidation (LPO) inhibitory activity of 18 flavonoids belonging to four classes namely flavones, isoflavones, flavonols and flavanones has been made with the help of PM3 calculations and geometry optimizations using CAChe software. Quantum-chemical descriptors were calculated by the same software using MOPAC 2002 engine. Two quantum-chemical descriptors, molar volume (M.V.) a...

Anil K. Srivastava*, Ratna Gupta , Rajneesh Srivastava and Dinesh K. Mishra

Department of Chemistry, M.L.K. (P.G.) College, Balrampur, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(8).2648-54

2648-2654

3960

1736

14.

FORMULATION AND EVALUATION OF CHRONOMODULATED COLONIC DRUG DELIVERY OF NIFIDIPINE

The pulsatile drug delivery works upon the system that releases active pharmaceutical ingredient completely and rapidly after a desired lag time. This type of approach was advantageous for: Drugswith extensive first pass metabolism and biological tolerance. Locally absorbed or acting drugs to a specific site in the intestinal tract (e.g. colon). Adaptation of therapy according to chronopharmacolog...

Renu Dinkar, Govind Mohan and Kumud Upadhyaya*

Department of Pharmaceutical Sciences , Kumaun University, Nainital, Uttaarkhand, India

DOI: 10.13040/IJPSR.0975-8232.6(4).1445-51

1445-1451

3960

1476

16.

SIMULTANEOUS ESTIMATION OF PARACETAMOL AND TAPENTADOL IN COMBINED DOSAGE FORM BY DERIVATIVE METHOD

Two simple, rapid, precise and accurate spectrophotometric methods have been developed for simultaneous analysis of Paracetamol (PCM) and Tapentadol (TAP) in their combined dosage form. Method A, First order derivative method involves measurement of absorbance at 257.060 nm (for TAP) and 289.406 nm (for PCM) in first order derivative spectra. Method B, Second order derivative method involves measu...

Vishal Khokhar* and R. M. Shah

Department of Quality Assurance, N. R. Vekaria Institute of Pharmacy, C. L. College Campus, Bilkha Road, Junagadh-362001, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(5).1777-81

1777-1781

3959

1775

17.

EVALUATION OF ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL ACTIVITY OF GARCINIA LANCIFOLIA ROXB.

Flavonoids have been reported to have many pharmacological activities, antimicrobial, antioxidant, cytotoxic, chemoprevention activities along with strong antiproliferative effects. The fruits of  Garcinia lancaefolia Roxb., family Cluseaceae , a plant endemic to Assam has been used in locally to treat many diseases for which it was selected for investigationg its antimicrobial properties. No sci...

T. Chowdhury* and P. J. Handique

Lecturer, Asian Institute of Management and Technology, Guwahati- 781 021, Assam, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(6).1663-67

1663-1667

3958

1814