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EFFECT OF EXPOSURE TO DI-BUTYL PHTHALATE ON REPRODUCTIVE PHYSIOLOGY IN ADULT FEMALE MOUSE
Di-butyl phthalate (DBP) is an environmental contaminant used in the production of plastics, cosmetics and medical devices. In the present study, the effects of exposure to DBP on reproduction of female mice were investigated. Adult female mice given DBP through gastric intubation at 0 (control), 250 (low dose) and 1000 (high dose) mg / Kg BW/ day for 10 days. After treatment, body weight and ovar...
4003
1839
HEMINTHOLYTIC POTENTIAL OF CYMBOPOGON CITRATUS LEAVES EXTRACT AND ITS FORMULATION AS AN EMULSION
The present communication deals with the laboratory studies carried out to determine the antihelmintic activity of Cymbopogon citratus leaves extracts against Pheritima posthuma. Methanolic and aqueous extracts were used as test solutions. Piperazine citrate was used as standard drug and normal saline as a control. Study involved the determination of time of paralysis as well as time of death of w...
4002
1810
EVALUATION OF ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL ACTIVITY OF GARCINIA LANCIFOLIA ROXB.
Flavonoids have been reported to have many pharmacological activities, antimicrobial, antioxidant, cytotoxic, chemoprevention activities along with strong antiproliferative effects. The fruits of Garcinia lancaefolia Roxb., family Cluseaceae , a plant endemic to Assam has been used in locally to treat many diseases for which it was selected for investigationg its antimicrobial properties. No sci...
4002
1828
FICUS BENJAMINA: PHYTOCHEMICAL AND PHARMACOGNOSTIC PERSPECTIVE
In the present study, phytochemical and pharmacological properties of species of F. benjamina have been discussed. The phytochemical and pharmacological properties correlate with various active constituents of the plant. Ficus belongs to the Moraceae family, found in Asia and Australia, and widely distributed in tropical and subtropical areas, including more than 800 species. The genus Ficus const...
4000
4841
EFFECT OF HYDRO-ALCOHOLIC ROOT EXTRACT OF PLUMBAGO ZEYLANICA L ALONE AND ITS COMBINATION WITH AQUEOUS LEAF EXTRACT OF CAMELLIA SINENSIS ON RESERPINE INDUCED PARKINSONISM
Aim: To investigate the antiparkinsonism activity of hydro alcoholic root extract of P. zeylanica L (PZE) alone and its combination with aqueous extract of C. sinensis leaves (AECS) in reserpine induced model. Materials and methods: Parkinsonism (PD) was induced by sub cutaneous administration of reserpine (1 mg/kg) for 5 days. The extracts/drugs being tested were administered orally (p.o) 60 min ...
3999
1712
ANOVULATORY FOLLICLE DEVELOPMENT IN ADULT ALBINO MICE DUE TO PROLONGED EXPOSURES TO GENISTEIN
Genistein is a soy phytoestrogen that mediates its functions by interacting with the endogenous estrogen receptor β. To investigate the effect of 10mg/kg body weight/ day genistein administration up to 90 days on the ovarian folliculogenesis and its correlation with serum gonadotropins and estrogen, adult Mus musculus were either administered with 1:4 DMSO : PBS (vehicle) or with 10mg genistein/k...
3998
1715
ELICITATION, BIOCONVERSION AND QUANTIFICATION OF BERBERINE FROM CISSAMPELOS PARIERA CALLUS CULTURES
Cissampelos pariera, an important medicinal plant was subjected to elicitation and bioconversion of precursors for the formation of Berberine, an important medicinal component. In vitro cultures of Cissampelos pariera, was successfully established using stem and leaf explants. MS Media fortified with IAA (2 mg/l) alone and MS media enriched with IAA (2mg/l) showed profuse callusing from leaf and s...
3998
1987
BIOCHEMICAL ANALYSIS IN PATIENTS WITH MAJOR DEPRESSIVE DISORDER IN JAMMU POPULATION
The study was conducted to study biochemical parameters in 42 major depressive disorder (MDD) patients, 22 males and 20 females (age range 18 - 55 years) visiting the Psychiatric Department, Government Medical College, Jammu. The smoking and alcohol intake was much lower (95.24% and 88.09%) in patients (both male and female) diagnosed with MDD. The well being status is also 76.19% satisfactory wit...
3998
1497
SYNTHESIS OF N-(ALKYL OR ARYL)-2-(1H-BENZOTRIAZOL-1-YL)-ACETAMIDES AS SELECTIVE COX-2 INHIBITOR
Microwave assisted organic synthesis (MAOS) has emerged as frontier in pharmaceutical research for synthesis of newer drugs and implementing GREEN chemistry. Arylacetamides are pharmaceutically interesting as they show various biological activities such as analgesic, local anesthetic, antiarthritic, antiarrhythmic activities, etc. In arylacetamides the nature of aromatic ring and its substituent i...
3997
1732
IMMUNOMODULATORY ACTIVITY OF LEAVES OF RUMEX VESICARIUS LINN. AND SYMPLOCOS RACEMOSA ROXB.
Objective: To determine the immunomodulatory activity of leaves of Rumex vesicarius Linn. and Symplocos racemosa Roxb. Methods: The ethyl acetate and ethanolic extract of Rumex Vesicarius Linn. and ethanolic and N-hexane extract of Symplocos racemosa Roxb. were administered orally at the dosage level of 200 mg/kg/day and 400 mg/kg/day each according to the body weight of Rat. The assessments of im...
3997
1838