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PRELIMINARY PHYTOCHEMICAL SCREENING AND GC MS ANALYSIS OF CHLOROFORM EXTRACT OF KANDELIA CANDEL (L.) DRUCE
The aim of the present study is to screen the phytochemicals present in the leaf extract of Kandelia candel and further analysis of the bioactive components present in it by Gas chromatography - Mass spectrometry (GC-MS) analysis. Carbohydrates, proteins, amino acids, Saponins, flavonoids, terpenoids, glycosides, tannins, alkaloids, and phenols were present in the sample. The percentage yield of p...
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FORMULATION OF COATED TABLETS OF DRY HAWTHORN EXTRACT AND THE DEVELOPMENT AND VALIDATION OF AN RP-HPLC METHOD FOR EVALUATING IT’S IN VITRO DISSOLUTION
Extracts of hawthorn (Crateagus sp.) have been indicated in the treatment of cardiovascular diseases, however, tablets produced from dry extract due to a multiple of factors such as inconsistent botanical ingredients, moisture content and hygroscopicity turn to be hard with prolong disintegration. Dissolution test is increasingly being employed for the assessment of solid herbal medicinal dosage f...
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INVESTIGATING THE LINK BETWEEN TRANSFORMATIONAL LEADERSHIP, PSYCHOLOGICAL EMPOWERMENT, AFFECTIVE COMMITMENT AND ORGANIZATIONAL CITIZENSHIP BEHAVIOR IN THE PHARMACEUTICAL SECTOR OF INDONESIA
Modern organizations face increasing competition due to globalization, technological change, politics and economics. In order to cope with these, public organizations, including organizations at the central and local government levels, must improve their efficiency and performance to reflect the presence of organization in other countries. Leaders, therefore, must act more quickly in encouraging a...
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ALLEVIATION OF ARSENIC INDUCED LUNG TOXICITY BY OCIMUM SANCTUM IN MURINE MODEL
Arsenic is a well known pulmonary irritant and has been found associated with lung cancer in smelter workers exposed to arsenic via inhalation. The recent findings suggest the involvement of reactive oxygen species (ROS), generated during arsenic metabolism in inducing arsenic toxicity. Thus present work was designed to establish a correlation between arsenic induced oxidative stress, histopatholo...
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THE HEATH RELATED QUALITY OF LIFE (HRQOL) FOR HYPERTENSIVE PATIENTS IN EASTERN PROVINCE IN SAUDI ARABIA: CROSS SECTIONAL STUDY
Background: Hypertension is associated with the flow of blood under high pressures, and is a risk factor for coronary heart disease. Methodology: We designed a prospective observational study that included 280 participants to investigate the effect of hypertension on the health-related quality of life (HRQOL) for hypertensive patients in the eastern province of KSA. To measure HRQOL, this study us...
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IN-VITRO EVALUATION OF ANTIBACTERIAL ACTIVITY OF CRUDE EXTRACT FROM THE STEM BARK OF ANNONA SENEGALENSIS PERS.
The antibacterial efficacy of the crude methanolic and aqueous extracts of Annona senegalensis, Pers on clinical isolates of E. coli, Salmonella enteriditis and Shigella dysenteriae were determined using Agar Well Diffusion technique on Mueller Hinton Agar (MHA) plates. At the concentration of between 100 and 200mg/ml, the methanolic extract inhibited the growth of all the organisms with an averag...
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ROLE OF ACUTE PHASE PROTEINS STATUS IN CHRONIC ALCOHOLIC LIVER DISEASES
Back ground: Alcoholic cirrhosis is a condition of irreversible liver disease due to the chronic inflammatory and toxic effects of ethanol on the liver. Acute alcoholic hepatitis occurs in habitual drinkers, often a period of increased alcohol intake. Although, the clinical features may mimic acute viral hepatitis. Progression of liver fibrosis to cirrhosis is dangerous as well as potentially life...
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ANTI-MICROBIAL AND ANTI ADHESIVE PROPERTIES OF LACTOBACILLUS AND BACILLUS SP.
The aim of this study was to determine the anti-microbial and anti-adhesive properties of a Lactobacillus and Bacillus, against several micro-organisms, including Gram-positive and Gram-negative bacteria. Biofilm producing micro- organisms were isolated from different samples. The isolated micro-organism were characterized and identified. The anti-microbial and anti-adhesive activities were determ...
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LEAD FINDING FROM WHOLE PLANT OF CURCUMA LONGA WITH OXIDATIVE POTENTIAL
The present study deals with the antioxidant activity, drug likeness score and bioactivity score of the compounds isolated from Curcuma longa and search lead antioxidant compound through molinspiration software. We have taken ten compounds from this plant. All the compounds were further subjected to molecular properties prediction and drug likeness by Molinspirstion and found in compliance with ...
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EVALUATION OF CARDIOPROTECTIVE EFFECTS OF CAMELLIA SINENSIS ON ISOPROTERENOL INDUCED MYOCARDIAL INFARCTION
Background: Black tea is rich in polyphenols which are antioxidants. The most abundant polyphenolic compounds are flavonols and catechins. Black tea antioxidants showed protective actions against chronic diseases like cardiovascular diseases due to their antioxidant action. Objective: The present study was conducted to evaluate the cardioprotective effects of Camellia sinensis on isoproterenol ...
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