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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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5.

BIOAVAILABILITY AND BIOEQUIVALENCE OF BIOSIMILARS

Biosimilars are the most promising medicines for treating complex diseases. The first biosimilar was approved in India in 2000, and since then, there is no looking back. CDSCO in collaboration with DBT has developed new guidelines in 2012, which were revised in 2016 for pre and post-marketing approval of biosimilars in India. India is one of the leading manufacturers of biosimilars catering to dom...

A. Arora * and A. Parle

Department of Quality Assurance, Delhi Institute of Pharmaceutical Sciences and Research, New Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.12(4).1989-00

1989-2000

3820

1649

12.

A REVIEW OF DIFFERENT DISSOLUTION METHODS

Dissolution is an authorized test used by Pharmacopoeias for assessing drug arrival of solid and semisolid measurement structures. The primary utilization of dissolution testing incorporates the biopharmaceutical portrayal of medication items as a device to guarantee reliable item quality and to predict in-vivo drug bioavailability. Dissolution testing was initially grown for solid orals; later on...

R. Thirumalaikumaran *, G. Lithikkaa and K. A. Kailash

Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences (DU), Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.14(11).5212-21

5212-5221

3820

1810

40.

DESIGN AND DEVELOPMENT OF IONTOPHORETIC DRUG DELIVERY SYSTEM OF L-TYROSINE

This study was aimed to design and develop iontophoretic drug delivery of L-Tyrosine in the treatment of phenylketonuria. The In-house iontophoretic drug delivery device was designed and validation was performed respect to Current intensity, Voltage, and Power Resistance. The study was also focused various parameters such as effect of different drug concentrations (2.5mg/5ml, 5mg/5ml, 10mg/5ml, 15...

N. Kirubakaran*, K. Reeta vijaya Rani, A. Anithaa and R. Senthamarai

Department of Pharmaceutics, Periyar college of Pharmaceutical Sciences, Trichy, Tamil Nadu, India.

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(12).5382-88

5382-5388

3819

1572

35.

BRINE SHRIM LETHALITY BIOASSAY OF METHANOLIC CRUDE EXTRACTS OF TERMINALIA ARJUNA

The aim of this work is to determine the cytotoxic activities of Terminalia arjuna (Family: Combretaceae) by brine shrimp lethality bioassay. The leaves of Terminalia arjuna were extracted with methanol and the methanolic extract was fractionated into three fractions by using organic solvents like n-hexane, ethyl acetate and chloroform. The n-hexane, ethyl acetate and chloroform soluble fractions ...

Md. Anaet Hossen Maruf and Mohammad Musarraf Hussain *

Assistant Professor, Department of Pharmacy, Jagannath University, Dhaka-1100 Bangladesh

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(11).4297-00

4297-4300

3819

1488

42.

PRELIMINARY PHYTOCHEMICAL SCREENING AND GC MS ANALYSIS OF CHLOROFORM EXTRACT OF KANDELIA CANDEL (L.) DRUCE

The aim of the present study is to screen the phytochemicals present in the leaf extract of Kandelia candel and further analysis of the bioactive components present in it by Gas chromatography - Mass spectrometry (GC-MS) analysis. Carbohydrates, proteins, amino acids, Saponins, flavonoids, terpenoids, glycosides, tannins, alkaloids, and phenols were present in the sample. The percentage yield of p...

T. K. Jasna*, P. R. Chandra and K. M. Khaleel

Department of PG Studies and Research in Botany, Sir Syed College, Taliparamba, Kannur, Taliparamba, Kerala, India

DOI: 10.13040/IJPSR.0975-8232.8(8).3530-33

3530-3533

3818

1763

7.

APPLICATION OF STEM CELL THERAPEUTIC AGENTS TO CONTROL CRITICAL DISEASE

Stem cell research has been hailed for the potential to revolutionize the future of medicine with the ability to regenerate damaged and diseased organs. On the other hand, stem cell research has been highly controversial due to the ethical issues concerned with the culture and use of stem cells derived from human embryos. This article presents an overview of what stem cells are, what roles they pl...

Sonam Sharma* and Ram Babu Tripathi

Institute of Biomedical Education and Research, Mangalayatan University, Beswan- Aligarh-202145, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(1).49-52

49-52

3816

1322

14.

EFFECT OF PROCESSING ON AMINO ACIDS CONTENTS OF FOUR SPECIES OF THE FAMILY CUCURBITACEAE

This study was carried out to evaluate the effect of boiling on amino acids contents of the fruits of four species of the family Cucurbitaceae which were Cucurbita maxima D, Cucurbita pepo L, Cucurbita moschata and Lagenaria siceraria variety supreme court. In this study, fresh fruit of the four species were subjected to conventional processing technique which is boiling as well as drying. The dry...

Ihsan Mohamed Elhadi , Mona A M Abd El Mageed * and Yahia Mohamed El Imam

Department of Pharmacognosy , Faculty of Pharmacy, Omdurman Islamic University, Sudan

DOI: 10.13040/IJPSR.0975-8232.6(9).3775-80

3775-80

3816

1697

15.

THE SYNERGESTIC EFFECTS OF EDTA / ANTIBACTERIAL COMBINATIONS IN KLEBSIELLA PNEUMONAE INDUCED PNEUMONIA RAT MODEL

The study was conducted to evaluate the synergistic effect of EDTA with antibacterial (Ceftriaxone + Sulbactum) as a combinational therapy against antioxidant enzyme activity, lipid peroxidation level, some hematological and biochemical parameters in Klebsiella pneumoniae induced nosocomial pneumonia followed by histopathology of lungs tissue in experimental exposed Sprague Dayle (S.D) rats. Total...

A. Kumar *, A. Choudhary, N. Mansoori, V. Dwivedi and M. Chaudhary

Department of Neurosurgery, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.9(8).3257-63

3257-3263

3816

2685

51.

TREATING DIABETES AND RHEUMATOID ARTHRITIS USING PERSONALIZED MEDICATION

As in the cases of non-communicable but chronic and autoimmune disorders like diabetes, cancer, anemia and rheumatoid arthritis are growing threat to humans. They depend on the genetic information and the genome sequence of the patients and other factors like environmental factors. In most of the cases, the pattern of the disease, i.e. pathogenesis is different for every individual, though phenoty...

S. U. Dani and P. A. Kulkarni *

Department of Pharmaceutics, SVKM’s NMIMS, School of Pharmacy & Technology Management, Shirpur, Dhule, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(12).5424-30

5424-5430

3816

1230

14.

CAUSES AND CONDITIONS ASSOCIATED WITH REDUCED LEVEL OF VITAMIN B12: A REVIEW

Vitamin B12 plays an important role in building of genetic material, in development of normal red blood cells and in maintenance of nervous system. Major deficiency symptoms of Vitamin B12 include anemia and neurological disorders. The daily recommended intake of vitamin B12 for an adult is 1.5μg a day. Eating a diet containing required amount of vitamin B12 is the best way to treat the condition...

Chandrakant Belwal

Sterling Biotech Research Center, Vadodara, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(10).3651-55

3651-3655

3815

1650