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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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35.

DISTINCT ENERGIES OF CHOLESTEROL

Cholesterol is a waxy substance which is made in the body by the liver but is also found in some foods. It plays a vital role in how every cell works and is also needed to make Vitamin D, some hormones and bile for digestion. The concept of energy of a graph was introduced by I. Gutman in the year 1978. In this paper, we compute Siedel Energy, Maximum Degree Energy, Distance Energy, Harary Energy ...

M. R. Rajesh Kanna*, D. Soner Nandappa and R. Pradeep Kumar

Department of Mathematics, Maharani's Science College for Women, Mysore, Karnataka, India

DOI: 10.13040/IJPSR.0975-8232.8(6).2612-18

2612-2618

3805

1497

42.

THE HEATH RELATED QUALITY OF LIFE (HRQOL) FOR HYPERTENSIVE PATIENTS IN EASTERN PROVINCE IN SAUDI ARABIA: CROSS SECTIONAL STUDY

Background: Hypertension is associated with the flow of blood under high pressures, and is a risk factor for coronary heart disease. Methodology: We designed a prospective observational study that included 280 participants to investigate the effect of hypertension on the health-related quality of life (HRQOL) for hypertensive patients in the eastern province of KSA. To measure HRQOL, this study us...

D. M. Alshayban, N. M. Alajmi, L. Y. Almarzooq, W. N. Altamimi, R. Joseph and F. H. Pottoo *

Department of Pharmacology, College of Clinical Pharmacy, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

DOI: 10.13040/IJPSR.0975-8232.10(12).5573-78

5573-5578

3805

1321

61.

SYNTHESIS AND SPECTRAL STUDIES OF Mn (II) COMPLEXES WITH 2-HEPTANONE SEMICARBAZONE AND THIOSEMICARBAZONE

Complexes of Manganese(II) of general composition Mn(L)2X2   have been synthesized with ligand 2-heptanone semicarbazone  and 2-heptanone thiosemicarbazone (where L = 2-heptanone semicarbazone or 2-hepatanone thiosemicarbazone and X=Cl-, SO42-, CH3COO-, NCS-, ClO4-) The IR spectral data of ligands indicate the involvement of sulphur/oxygen and nitrogen in coordination to the central metal. The ...

Pravita Kumar, Archana and Sulekh Chandra*

Department of Chemistry, Zakir Husain Delhi College, JLN Marg New Delhi-110002, ‬India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(6).2552-58

2562-2568

3804

1595

29.

PHARMACOGNOSTIC CHARACTERIZATION OF STEM AND ROOT OF ADHATODA ZEYLANICA MEDICUS

Adhatoda zeylanica Medicus is a well-known plant drug in Ayurvedic, Unani-Tibbi, Siddha, Allopathic, Homeopathic, Naturopathic & Home Remedies. The present communication deals with the pharmacognostic evaluation on the stem and root of Adhatoda zeylanica Medicus (Acanthaceae). Macroscopic and microscopic examinations of the different organ, observations, and differential microchemical test has...

D.A. Dhale* and R.K. Kalme

Assistant Professor, PG-Department of Botany, S.S.V.P.S. Sansthas, L.K.Dr.P.R.Ghogrey Science College, Dhule-424005, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(11).4264-69

4264-4269

3804

2734

13.

A STUDY ON FEASIBILITY OF OPTIMIZATION TECHNIQUE IN FORMULATION OF DISPERSIBLE TABLETS BY FACTORIAL DESIGN

In the present research work an attempt was made to study the effect of formulation variables in the development of dispersible tablet by using various super disintegrants. Instead of normal trial and error method an optimization technique was adapted. Amount of Crosscarmellose sodium, SSG and MCC were included as independent variables and hardness, percentage friability, disintegration time and w...

R.E. Ugandar*, Kiran C. Nilugal, Nagarajan Srinivasan and Nagashekhara Molugulu

Faculty of Pharmacy, Asia Metropolitan University, G-8, Jalan Kemacahaya, Taman Kemacahaya, Batu 9, Cheras- 43200, Selangor, Malaysia

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1208-27

1208-1227

3803

1613

7.

APPLICATION OF STEM CELL THERAPEUTIC AGENTS TO CONTROL CRITICAL DISEASE

Stem cell research has been hailed for the potential to revolutionize the future of medicine with the ability to regenerate damaged and diseased organs. On the other hand, stem cell research has been highly controversial due to the ethical issues concerned with the culture and use of stem cells derived from human embryos. This article presents an overview of what stem cells are, what roles they pl...

Sonam Sharma* and Ram Babu Tripathi

Institute of Biomedical Education and Research, Mangalayatan University, Beswan- Aligarh-202145, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(1).49-52

49-52

3803

1321

41.

ISOLATION OF CONTINENTALIC ACID FROM ARALIA CACHEMIRICA AND ITS IMMUNO-BIOLOGICAL EVALUATION

In continuing search for compounds with immunomodulatory activity, plant Aralia cachemirica has been found to contain continentalic acid (CA). Isolation of this pharmacologically significant diterpinic acid from Aralia cachemirica is novel. Chemical structure of this compound was identified by spectral analysis as (-)-pimara-8(14), 15-dien-19-oic acid, which has been isolated from A. cordata and A...

Ekta Sharma , Bhupinder Singh Arora , Anamika Khajuria , Tabasum Sidiq , Dharma Kishore * and Ram A. Vishwakarma

Professor, Department of Chemistry, Banasthali University, P.O. Banasthali Vidyapith, Tonk-304022, Rajasthan, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(8).2183-89

2183-2189

3803

1670

17.

FORMULATION OF COATED TABLETS OF DRY HAWTHORN EXTRACT AND THE DEVELOPMENT AND VALIDATION OF AN RP-HPLC METHOD FOR EVALUATING IT’S IN VITRO DISSOLUTION

Extracts of hawthorn (Crateagus sp.) have been indicated in the treatment of cardiovascular diseases, however, tablets produced from dry extract due to a multiple of factors such as inconsistent botanical ingredients, moisture content and hygroscopicity turn to be hard with prolong disintegration. Dissolution test is increasingly being employed for the assessment of solid herbal medicinal dosage f...

M.O. Aggrey, Z. Liu *, R. Zhang , C.I. Okeke L. Ma N. Li and L. Li

Associate Professor, Tianjin State Key Laboratory of Modern Chinese Medicine, 88 Yuquan Road, Tianjin, P.R. China

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(10).3676-85

3676-3685

3802

1721

15.

THE SYNERGESTIC EFFECTS OF EDTA / ANTIBACTERIAL COMBINATIONS IN KLEBSIELLA PNEUMONAE INDUCED PNEUMONIA RAT MODEL

The study was conducted to evaluate the synergistic effect of EDTA with antibacterial (Ceftriaxone + Sulbactum) as a combinational therapy against antioxidant enzyme activity, lipid peroxidation level, some hematological and biochemical parameters in Klebsiella pneumoniae induced nosocomial pneumonia followed by histopathology of lungs tissue in experimental exposed Sprague Dayle (S.D) rats. Total...

A. Kumar *, A. Choudhary, N. Mansoori, V. Dwivedi and M. Chaudhary

Department of Neurosurgery, Dr. Ram Manohar Lohia Hospital, New Delhi, Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.9(8).3257-63

3257-3263

3802

2679

13.

ANTI- DIABETIC ACTIVITY OF BRUGUIERA GYMNORHIZA ROOT

The different extracts of the roots of Bruguiera gymnorhiza (Family- Rhizophoraceae) were tested for anti-diabetic activity, by glucose tolerance test in normal rats and alloxan induced diabetic rats. Aqueous ethanol and butanol extracts had shown significant protection and lowered the blood glucose levels to normal in glucose tolerance test. In alloxan induced diabetic rats the maximum reduction ...

Namrata Singh , Atul Vikram Patel, Shashi Alok, Pushpendra Kannojia

Pranav Institute of Pharmaceutical Sciences and Research, Gwalior (MP), India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.1(5).115-19

115-119

3801

1532