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BENEFICIAL EXPLORATION OF NATURAL PESTICIDES FROM HIGHER PLANT
The methanolic extract (MeOH) of the bark of Holoptelea integrifolia (Roxb.) Planch and its partitions namely n-hexane (Hx), ethyl acetate (EtOAC), butanol (BuOH) and water (H2O) was screened for various in vitro biological activities including general cytotoxicity (brine shrimp lethality assay), phytotoxicity (lemna minor bioassay), nematicidal and insecticidal (Tribolium castaneum H., Rhyzoperth...
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ANTIDIARRHOEAL ACTIVITY, NITRIC OXIDE SCAVENGING AND TOTAL TANNIN CONTENT FROM THE BARK OF CERIOPS DECANDRA (GRIFF.) DING HOU
The present study was designed to investigate the antidiarrhoeal, nitric oxide scavenging and total tannin content from the ethanolic extract of the bark of Ceriops decandra (Griff.) Ding Hou (Family: Rhizophoraceae). The ethanol extract at graded doses (200 & 400 mg/kg body weight) was investigated for antidiarrhoeal activity in term of reduction in the rate of defecation and consistency of f...
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DISTINCT ENERGIES OF CHOLESTEROL
Cholesterol is a waxy substance which is made in the body by the liver but is also found in some foods. It plays a vital role in how every cell works and is also needed to make Vitamin D, some hormones and bile for digestion. The concept of energy of a graph was introduced by I. Gutman in the year 1978. In this paper, we compute Siedel Energy, Maximum Degree Energy, Distance Energy, Harary Energy ...
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A STUDY ON FEASIBILITY OF OPTIMIZATION TECHNIQUE IN FORMULATION OF DISPERSIBLE TABLETS BY FACTORIAL DESIGN
In the present research work an attempt was made to study the effect of formulation variables in the development of dispersible tablet by using various super disintegrants. Instead of normal trial and error method an optimization technique was adapted. Amount of Crosscarmellose sodium, SSG and MCC were included as independent variables and hardness, percentage friability, disintegration time and w...
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PHYTOCHEMICAL SCREENING ON THE AERIAL PART OF THE LUFFA ECHINATA LINN.
The present work deals with development and standardization of phytochemical screening for quantification of ethanolic extract of aerial part of the Luffa echinata Linn. The scientific parameter is necessary to identify the exact plant material and to find its quality and purity. The present study deals with various, physical evaluation and preliminary phytochemical screening of various successive...
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COMPARATIVE EFFECTIVENESS OF SIMULATION BASED TEACHING VERSUS CONVENTIONAL TEACHING FOR UNDERGRADUATE STUDENTS OF SECOND PROFESSIONAL M.B.B.S IN EXPERIMENTAL PHARMACOLOGY
Aims: To evaluate and analyze effectiveness of animal simulation based teaching in pharmacology in comparison to conventional methods to undergraduate medical students. Methods: An interventional and comparative study was conducted among second professional MBBS students. All students were divided into two groups A and B. Four demonstrations of experimental pharmacology were demonstrated by conven...
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ANTI- INFLAMMATORY, ANALGESIC & ULCEROGENIC ACTIVITY OF KETOPROFEN GLUCOPYRANOSIDE CONJUGATES
Ketoprofen is a non-steroidal anti-inflammatory drug. Glucopyranoside Conjugates of Ketoprofen have been synthesized and evaluated for anti- inflammatory, analgesic and ulcerogenic activities. In vivo biological screening in mice and rats indicated that conjugates improved analgesic and anti-inflammatory activities with significantly reduced ulcerogenicity compared to the parent drug....
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SYNTHESIS AND PHARMACOLOGICAL ACTIVITY EVALUATION OF OXADIAZOLES CONTAINING SUBSTITUTED DIHYDROPYRIMIDINONE AND CHLOROQUINOLINE MOITIES
In the present paper, synthesis of new series of 1,3,4- oxadiazole derivatives incorporating substituted dihydropyrimidinone and chloroquinoline moieties 4(a-j) has been reported. All the synthesized compounds were characterized by FTIR, 1H NMR and Mass spectroscopy. The compounds were screened for their in vivo anti-inflammatory activity by the carrageenan induced rat paw edema method and in vitr...
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CAUSES AND CONDITIONS ASSOCIATED WITH REDUCED LEVEL OF VITAMIN B12: A REVIEW
Vitamin B12 plays an important role in building of genetic material, in development of normal red blood cells and in maintenance of nervous system. Major deficiency symptoms of Vitamin B12 include anemia and neurological disorders. The daily recommended intake of vitamin B12 for an adult is 1.5μg a day. Eating a diet containing required amount of vitamin B12 is the best way to treat the condition...
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THE SYNERGESTIC EFFECTS OF EDTA / ANTIBACTERIAL COMBINATIONS IN KLEBSIELLA PNEUMONAE INDUCED PNEUMONIA RAT MODEL
The study was conducted to evaluate the synergistic effect of EDTA with antibacterial (Ceftriaxone + Sulbactum) as a combinational therapy against antioxidant enzyme activity, lipid peroxidation level, some hematological and biochemical parameters in Klebsiella pneumoniae induced nosocomial pneumonia followed by histopathology of lungs tissue in experimental exposed Sprague Dayle (S.D) rats. Total...
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