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NANOEMULSION: A NOVEL TRAIT IN THE TREATMENT OF SKIN AGEING
Nanoemulsion system is a promising vehicle due to the powerful ability to deliver the drug through the skin. Researchers have been conducted to prove its potential for the delivery of the drugs used in many skin disorders. Skin is the largest organ and acts as the first line of defense of our body. After a certain period of time, our skin loses tone and elasticity which is called aging. It is the ...
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2067
GASTRIC ULCER PROTECTIVE EFFECT OF MADHUCA LATIFOLIA ROXB BARK IN WISTAR RATS
The present study was carried out to investigate the protective effect of ethanolic extract of Madhuca latifolia (Roxb.) bark (MLE) and aqueous extract of Madhuca latifolia (Roxb.) bark (MLA) in aspirin-induced gastric ulcer. In both extract, acute toxicity performed according to guidelines for the selection of doses. The oral administration (400 mg/kg) of MLE & MLA extract reduced the ulcer i...
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EVALUATION OF ANTIDIABETIC ACTIVITY OF PICRORHIZA SCROPHULARIIFLORA PENNELL IN HIGH FAT FED DIET WITH STREPTOZOTOCIN INDUCED TYPE II DIABETIC RATS
High energy-intake is a major factor revolved in type 2 diabetes. The objectives of this study is to set up a suitable animal model, which is similar to the human type 2 diabetes, 6 - 8 weeks old Sprague Dawley rats weighing 220 - 250 gm were consumed high fat diet (HFD) of 20% fat, 46% carbohydrate and 20% protein (w/w). Two weeks later the animals were given with intraperitonial injection of str...
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ASSESSMENT OF PHYSICO-CHEMICAL STATUS OF GROUND WATER SAMPLES OF PARBHANI DISTRICT (M.S., INDIA)
Ground water is the most preferred water source in recent day. Once believed to be safe from pollution as it is available many strata below the surface, is now provided to be prone to pollution by many researchers across the world. The contamination of ground water may be due to improper disposal of domestic and industrial west water. A study was carried out to assess the ground water quality of P...
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ASSESSMENT OF KNOWLEDGE, ATTITUDE AND PRACTICE OF PRESCRIBING FIXED DOSE COMBINATIONS AMONG POSTGRADUATE MEDICAL STUDENTS – A CROSS SECTIONAL SURVEY
Objective: To evaluate the knowledge, attitude and practice, regarding Fixed Dose Combinations (FDCs) among Postgraduate medical students of Bangalore Medical College and Research Institute, Bengaluru. Materials and methods: The questionnaire based study was conducted among 150 Postgraduate medical students of BMCRI, Bengaluru. The data obtained was analyzed using descriptive statistics. Results: ...
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OPTIMIZATION OF EFFECT OF SUPERDISINTEGRANTS AND SUBLIMING AGENT ON ORODISPERSIBLE TABLET OF ONDANSETRON RESINATE
Ondansetron is a serotonin 5HT3 antagonist; anti emetic drug. Bitter taste of the ondansetron is a major problem in ensuring patient compliance. Resinates of ondansetron were prepared with Indion 234 and loading process was optimized. A 3² factorial design was used for formulation development of orodispersible tablet of these taste masked resinates. The amount of subliming agent (camphor) and sup...
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SIMULTANEOUS ESTIMATION OF DICLOFENAC SODIUM AND ESOMEPRAZOLE MAGNESIUM TRIHYDRATE IN BULK DRUG AND IN SYNTHETIC MIXTURE BY SPECTROPHOTOMETRY
Two simple, rapid, precise and accurate spectrophotometric methods have been developed for simultaneous estimation of Diclofenac Sodium (DIC) and Esomeprazole Magnesium Trihydrate in bulk drugs and synthetic mixture. Method A, Simultaneous equation method (Vierodt’s method) applies measurement of absorptivities at two wavelengths, 280.00 nm, (λmax of Diclofenac Sodium) and 301.00 nm,( (λmax of...
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ANTI-MICROBIAL AND ANTI ADHESIVE PROPERTIES OF LACTOBACILLUS AND BACILLUS SP.
The aim of this study was to determine the anti-microbial and anti-adhesive properties of a Lactobacillus and Bacillus, against several micro-organisms, including Gram-positive and Gram-negative bacteria. Biofilm producing micro- organisms were isolated from different samples. The isolated micro-organism were characterized and identified. The anti-microbial and anti-adhesive activities were determ...
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ASSESSMENT OF VITAMIN D ON METABOLIC DISORDERS IN ARTHRITIC PREDIABETIC PATIENTS- A PHARMACOLOGICAL APPROACH
We planned to clarify the association between the Vitamin D supplementation and predisposition of metabolic syndrome including obesity, diabetes mellitus, hypertension and dyslipidemia in arthritic patient with pre diabetic condition and to assess prediabetes interfere in the disease progression. Retrospective observational study was conducted on 236 patients. Of these, Arthritis patients with no ...
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THE PROTECTIVE EFFECTS ABELMOSCHUS ESCULENTUS PODS SKIN AND SEEDS AGAINST NICOTINE INDUCED LIVER, KIDNEY DAMAGE IN MICE’
Abelmoschus esculentus is one of the oldest urbane crops grown in many countries and widely distributed. Parts used of okra are fruit, leave seed, root wish showed to have numerous Medicinal significant uses. On the other hand, cigarette, smokers found to have a high a significant effect on liver kidney and other numerous organs in the body. Aim: The study aims to explore the possible protective e...
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