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A STUDY OF ETHNOMEDICINAL PLANT DIVERSITY OF SACRED NATURAL SITES OF PANCHKOSHI PILGRIMAGE OF VARANASI, UTTAR PRADESH INDIA
Introduction: Medicinal plants have always played a major role in primary health care system since time immemorial. Sacred natural sites is the prime place to encompass large medicinal plant with wide range of natural resources. It potentially conserves plant biodiversity with inclusion of sacred places and sacred water bodies. Apart from social and religious importance it, regulate air and water ...
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HAEMOVIGILANCE: STEPPING STONE TOWARDS BLOOD SAFETY- INDIAN SCENARIO
Blood transfusion is an important part of various treatment protocols. Blood should be transfused with certain precautions like drug because blood and its constituents have the propensity to cause effects like introduction of donor antigens within the recipient, transfusion reactions or exposure to numerous transfusion-transmitted diseases. Thereby, it is important for the clinicians to remember t...
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RP-HPLC METHOD FOR ESTIMATION OF ROSUVASTATIN CALCIUM FROM BULK AND TRANSDERMAL DOSAGE FORM
A RP-HPLC method was developed for estimation of rosuvastatin calcium and validated as per ICH guidelines. The estimation was carried out on C-18 Reliant (4.6 × 250 mm, 5 µm) column using a filtered and degassed mixture of acetonitrile: phosphate buffer pH 2.6 (in the ratio 70:30) as the mobile phase at a flow rate of 1.0 ml/min. The detection was carried out at wavelength of 241 nm. The method ...
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FORMULATION DEVELOPMENT AND EVALUATION OF MUCOADHESIVE FILMS OF ZOLMITRIPTAN
Formulation development for new drugs, an extension of formulations, finding an alternative to conventional dosage forms for better therapeutic response are some of the research impetus in Pharmaceutical F and D. The new -untried routes of administration are also an avenue that can be explored. Under this research zolmitriptan, an antimigraine, BCS class II drug is formulated into mucoadhesive fil...
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PATIENT- REPORTED ADVERSE EFFECTS TO ANTI RETROVIRAL DRUGS IN A SPECIALIST HOSPITAL, NORTH WEST NIGERIA
Patients experiencing adverse effects are less likely than those not experiencing it to adhere to treatment. However little is known about the adverse drug reactions to many HIV programme in developing countries, indicating the need for Antiretroviral (ART) safety surveillance. The study is a retrospective analysis of records of adverse reactions by patients initiated on ART. A total of 1870 patie...
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PREPARATION AND EVALUATION OF CYCLODEXTRIN COMPLEXATION OF ETORICOXIB
Cyclodextrin complexes of etoricoxib (poorly water soluble COX-2 inhibitor) were prepared with the β-CD and HPβ-CD by different techniques (physical mixture, kneading and co-evaporation methods) at 1:1 and 1:2 molar ratios. Characterization of the complexes was done in solution by phase solubility analysis and in solid state using FTIR. The stoichiometry and stability constants of ECB-β-CD (1:1...
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PROSPECTIVE OBSERVATIONAL, NON-RANDOMIZED, PARALLEL SEQUENCE STUDY FOR ASSESSMENT OF ADVERSE DRUG REACTIONS DUE TO CHEMOTHERAPEUTIC TREATMENT IN DIFFERENT TYPES OF CANCER PATIENTSABSTRACT
Objective: To assess incidence, causality, severity, predictability and preventability of adverse drug reactions (ADRs) in hospitalised oncology patients. Materials and Methods: A prospective observational, non-randomized, parallel sequence study was conducted at Dr B. Borooah Cancer Institute (BBCI) after getting an approval from human ethical committee. Patients hospitalised at BBCI from Aug ...
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GC MS ANALYSIS AND ANTIMICROBIAL ACTIVITY OF SEED OIL OF BROUSSONETIA PAPYRIFERA (L.) VENT
The current study focuses on evaluating chemical composition and antimicrobial activity of seed oil of Broussonetia papyrifera; a widely used Chinese medicinal plant. The chemical constituents of the oil were evaluated by GC‑MS analysis. Antimicrobial activity and minimum inhibitory concentrations were determined by disk diffusion and agar dilution methods. The seed oil contains 46 different p...
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PROTECTIVE PROFILE OF HYDNOCARPUS LAURIFOLIA ON STREPTOZOTOCIN INDUCED OXIDATIVE STRESS IN RATS
The present study was aimed to evaluate the anti-oxidative defence system of Hydnocarpus laurifolia in diabetic rats and its potential effect against the β-cell damage induced by oxidative stress. Hydnocarpus laurifolia is a plant which belongs to the family Flacourtiaceae. According to the Indian system of traditional medicine it is used in the treatment of diabetes mellitus. Also literature rev...
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BIOSORPTION OF As (III) BY ASPERGILLUS NIGER X300 USING COMPLEX NUTRIENT MEDIUM
An experimental study was carried out to select a suitable complex nutrient medium for growth and As(III) biosorption by an As(III) resistant strain Aspergillus niger X300 .For this purpose different complex nutrient were examined one by one. The recommended complex nutrients (gm%) were corn steep liquir, 20; rice bran extract, 10; paddy soak liquir, 10; wheat bran extract, 15 beef extract, 30, me...
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