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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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47.

PROSPECTIVE OBSERVATIONAL, NON-RANDOMIZED, PARALLEL SEQUENCE STUDY FOR ASSESSMENT OF ADVERSE DRUG REACTIONS DUE TO CHEMOTHERAPEUTIC TREATMENT IN DIFFERENT TYPES OF CANCER PATIENTSABSTRACT

Objective: To assess incidence, causality, severity, predictability and preventability of adverse drug reactions (ADRs) in hospitalised oncology patients. Materials and Methods: A prospective observational, non-randomized, parallel sequence study was conducted at Dr B. Borooah Cancer Institute (BBCI) after getting an approval from human ethical committee. Patients hospitalised at BBCI from Aug ...

Mrugank B.P. *and Hareesha R.P.

Clinical Research Scientist, Division of Research and Development, Alembic Pharmaceuticals Limited, Vadodara, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(1).386-91

386-391

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24.

BIOSORPTION OF As (III) BY ASPERGILLUS NIGER X300 USING COMPLEX NUTRIENT MEDIUM

An experimental study was carried out to select a suitable complex nutrient medium for growth and As(III) biosorption by an As(III) resistant strain Aspergillus niger X300 .For this purpose different complex nutrient were examined one by one. The recommended complex nutrients (gm%) were corn steep liquir, 20; rice bran extract, 10; paddy soak liquir, 10; wheat bran extract, 15 beef extract, 30, me...

S. Ganguly

Department of Biological Sciences, Sankrail Abhoy Charan High School (H.S.), Sankrail, Howrah, West Bengal, India

DOI: 10.13040/IJPSR.0975-8232.4(7).2648-51

2648-2651

3935

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45.

PHYSICAL, CHEMICAL AND PHYSICO-CHEMICAL CONTROL OF HELIOTROPIUM INDICUM LINN., BORAGINACEAE, POWDER AND TINCTURE

The quality control of herbal drugs and their extracts is essential when they are used as raw material for the development of herbal medicines. In this work, several techniques (pharmacopoeial and non-pharmacopoeial) were performed, aiming at establishing quality control parameters of the leaves of Heliotropium indicum L. (Boraginaceae), a shrub popularly known as stinker (fedegoso) in Brazilian n...

R. S. Costa , S. R. P. Camelo , R. M. Ribeiro-Costa , W. L. R. Barbosa , F. Vasconcelos , J. O. C. Silva Júnior

Department of Pharmacy, Laboratory R & D Pharmacotechniques and Pharmaceutical Technology, Federal University of Pará, Brazil

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.2(8).2211-16

2211-2216

3935

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29.

ANTIOXIDANT POTENTIAL OF TRAGIA INVOLUCRATA LINN ON STREPTOZOTOCIN INDUCED OXIDATIVE STRESS IN RATS

In Traditional Ayurvedic system of treatment Tragia involucrata Linn. is intended to use for diabetic patients has been screened for antioxidant activity. For antioxidant studies, aqueous ethanolic extract of Tragia involucrata (AEETI) was administered orally for 28 days at a dose of 250 and 500 mg/kg body weight to Streptozotocin- Nicotinamide induced Wistar rats. All the animals were sacrificed ...

S. Mohamed Farook* and W. Clement Atlee

Department of Pharmacology, C. L. Baid Metha College of Pharmacy, Thuraipakam, Chennai, Tamil Nadu, India

DOI: 2http://dx.doi.org/10.13040/IJPSR.0975-8232.2(6).1530-36

1530-1536

3934

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23.

INFLUENCE OF FLUCONAZOLE PRE-TREATMENT ON ANTIDIABETIC ACTIVITY OF THIAZOLIDINEDIONES IN DIABETIC RATS

The influence of fluconazole pre-treatment on the hypoglycaemic effect of pioglitazone (10 mg/kg, p.o) and rosiglitazone (720µg/kg, p.o) was studied. This study was conducted on diabetic rats of either sex, randomly distributed into two different groups. Diabetes was induced by administering 120mg/kg of alloxan intraperitonially. Then they were pretreated with fluconazole (36 mg/kg) in 2% w/v gum...

A. K. Patel *, J. Kaur, D. K. Yadav, M. Hasan and P. K. Tyagi

College of Pharmacy, Shree Ganpati Institute of Technology, Hapur, UP, India

DOI: 10.13040/IJPSR.0975-8232.7(11).4480-84

4480-84

3934

1628

26.

FORMULATION AND EVALUATION OF CUBOSOMAL GEL FOR TOPICAL APPLICATION

The present research aims to develop a transdermal Cubosomal gel formulation of Indomethacin, which would attenuate the gastrointestinal toxicities associated with oral administration and also aimed to encapsulate high drug pay load in Cubosomes for improved therapeutic efficiency. Indomethacin is an NSAID commonly recommended for the relief of pain and inflammation. Indomethacin was formulated as...

S. Shahana, Alkka Anna Sabu * and Preetha Mathew

Department of Pharmaceutics, Nazareth College of Pharmacy, Othera P.O Thiruvalla, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.15(2).518-25

518-525

3933

2136

35.

ANTIHYPERGLYCEMIC, ANTIOXIDANT AND ANTIDYSLIPIDEMIC PROPERTIES OF HEMIDESMUS INDICUS ROOT EXTRACT STUDIED IN ALLOXAN-INDUCED EXPERIMENTAL DIABETES IN RATS

Diabetes mellitus is a chronic metabolic disorder associated with hyperglycemia, oxidative stress and dyslipidemia. Hemidesmus indicus is employed as an indigenous medicine for a variety of ailments from earlier days. The present study was aimed to evaluate the role of Hemidesmus indicus in alloxan-induced experimental diabetic rats. The effect of oral administration of Hemidesmus indicus root ext...

S. Subramanian*, A. Abarna and V. Thamizhiniyan

Assistant Professor, Department of Biochemistry, University of Madras, Guindy campus, Chennai-600 025, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(1).227-34

227-234

3932

1596

52.

X-RAY DIFFRACTION STUDY OF A PANCHAVAKTRA RAS

Analytical monitoring of Pharmaceutical products is necessary to ensure its safety and efficacy throughout all phases of the drug. A systematic approach should be adapted to the presentation and evaluation of stable information, which should include, as necessary, physical, chemical, biological and microbiological test characteristics. Indian System of Medicine (ISM) frequently uses metal/mineral ...

B. Srinivasulu*, P. Bhadra Dev, P.H.C. Murthy

P.G. Department of Rasa-Shastra, Dr. N.R.S. Government Ayurvedic College, Vijayawada, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(6).1853-59

1853-1859

3932

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51.

EVALUATION OF ANTIMICROBIAL POTENTIAL OF BAUHINIA BLAKEANA FLOWERS

In this study, the phytochemicals and their antimicrobial potential of flowers of Bauhinia blakeana of Fabaceae Family were evaluated. The selected microbes for the antimicrobial study were E. coli, Enterobacter sp., Proteus sp., and Klebsiella sp. Ethanolic extract was prepared by continuous hot percolation method using Soxhlet extractor, and Antimicrobial activity was tested by Agar well diffusi...

D. V. S. Elezabeth and P. Ramachandran *

PG & Research Department of Chemistry, Nehru Memorial College, Puthanampatti , Tiruchirappalli, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.5(9).3932-35

3932-3935

3931

1726

29.

COMPARATIVE STUDY OF PHENOLICS AND ANTIOXIDANT ACTIVITY OF PHYTOCHEMICALS OF T.CHEBULA EXTRACTED USING MICROWAVE AND ULTRASONICATION

The extraction of active compounds from plants is one of the most critical steps in the commercial development of natural products for medicinal and health benefits. In view of the large number of plant species potentially available for study, it is essential to have efficient systems for the rapid and efficient extraction of phytochemicals for further investigation on their properties. The presen...

R. Thomas*, R. Tripathi, S. D. Kamat and D. V. Kamat

Department of Biotechnology, Mithibai College of Arts, Chauhan Institute of Science and Amrutben Jivanlal College of Commerce & Economics, Vile Parle (West), Mumbai- 400 056, Maharashtra, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(1).194-97

194-197

3930

1460