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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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34.

ANTIDIABETIC EFFECT OF ETHANOLIC SEED EXTRACT OF DECALEPIS HAMILTONII WIGHT AND ARN ON OXIDATIVE STRESS AND ENZYMIC ACTIVITIES IN ALLOXAN INDUCED DIABETIC RATS

Decalepis hamiltonii Wight and Arn. is an indigenous medicinal plant, which has a folk reputation in Western and southern India as hypoglycemic agent. The present investigation was carried out to evaluate the antidiabetic effect of ethanolic seed extract of Decalepis hamiltonii in alloxan induced diabetic Albino rats. Blood glucose levels and body weights of control and diabetic rats were monitore...

A. Rayar * and R. Manivannan

Department of Chemistry, Government Arts College (Autonomous), Kumbakonam, Tamilnadu State, India

DOI: 10.13040/IJPSR.0975-8232.7(1).292-99

292-299

3950

2005

4.

OROXYLUM INDICUM: AN OVERVIEW

Oroxylum indicum (O. indicum), commonly known as the Indian trumpet tree, belonging to the family Bignoniaceae, is a medicinally important, small, or medium-sized plant used to treat various diseases and also has its importance in the traditional system of medicine. Various parts of the plant have been proved to possess useful pharmacological activities. It is native to the Indian subcontinent, ex...

V. G. Kanase *, P. M. Pandagale and S. M. Dani

Department of Pharmacology, Oriental College of Pharmacy, Sanpada, Navi Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.13(6).2242-50

2242-2250

3950

2586

3.

GLOBAL PERSPECTIVES ON MEDICAL DEVICE REGULATIONS: A COMPARATIVE STUDY OF US, CANADA, EUROPE, INDIA, AND JAPAN

This review paper compares medical device regulations across the United States (US), Canada, Europe, India, and Japan. It offers an understanding of the many regulatory frameworks that control the approval processes for medical devices, the Competent Authorities, the rules and regulations, the licensing or registration processes, the classification systems for devices, and the quality management/G...

Rounak Bhattacharya, Subhadeep Parua *, Debkanta Das, Satyasis Majumder, Sudip Mukherjee and Rudrajit Saha

School of Pharmacy, Seacom Skills University, Bolpur, West Bengal, India.

DOI: 10.13040/IJPSR.0975-8232.15(11).3148-64

3148-3164

3949

2222

5.

GENE THERAPY, RECENT DEVELOPMENT AND FUTURE PROSPECTS IN GASTROINTESTINAL ONCOLOGY: A REVIEW ARTICLE

The introduction of nucleic acids into cells has as a purpose of medical condition or disease. Currently, gene therapy studies a broad range of potential therapeutic interventions, including the body's immune reaction to tumours, new blood vessels in the heart to alleviate heart attacks and to stop HIV-replication in patients with AIDS1 .There is also renewed emphasis on the gene therapy of geneti...

Kotla Ramya Sree and Mudavath Hanumanaik

Department of Pharmaceutical Chemistry KLE University College of Pharmacy, Vidyanagar, Hubli, Karnataka, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(2).558-74

558-574

3949

1697

22.

IMMUNOMODULATORY ACTIVITY OF LEAVES OF RUMEX VESICARIUS LINN. AND SYMPLOCOS RACEMOSA ROXB.

Objective: To determine the immunomodulatory activity of leaves of Rumex vesicarius Linn. and Symplocos racemosa Roxb. Methods: The ethyl acetate and ethanolic extract of Rumex Vesicarius Linn. and ethanolic and N-hexane extract of Symplocos racemosa Roxb. were administered orally at the dosage level of 200 mg/kg/day and 400 mg/kg/day each according to the body weight of Rat. The assessments of im...

J. Y. Manure* and N. S. Naikwade

Department of Pharmaceutical Chemistry, Appasaheb Birnale College of Pharmacy, Sangli, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.9(4).1537-44

1537-1544

3949

1804

9.

NON-INFERIORITY OF NEBULIZED COLISTIN COMPARED WITH CONVENTIONAL SYSTEMIC ANTIBIOTICS FOR THE TREATMENT OF VENTILATOR-ASSOCIATED PNEUMONIA

Background: In the present study, our objective was to determine whether nebulized colistin as an adjunctive therapy to conventional intravenous antibiotics of Ventilator-associated pneumonia (VAP) caused by multi-drug resistant (MDR) was safe and beneficial in critically ill patients. Methods: A prospective matched case-control study was performed at the ICUs of the University Hospital of Isfahan...

B. Alikiaie, S. Mousavi * and N. Yeilaghian

Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.

DOI: 10.13040/IJPSR.0975-8232.9(6).2221-27

2221-2127

3949

1929

4.

HAEMOVIGILANCE: STEPPING STONE TOWARDS BLOOD SAFETY- INDIAN SCENARIO

Blood transfusion is an important part of various treatment protocols. Blood should be transfused with certain precautions like drug because blood and its constituents have the propensity to cause effects like introduction of donor antigens within the recipient, transfusion reactions or exposure to numerous transfusion-transmitted diseases. Thereby, it is important for the clinicians to remember t...

P. P. Anagha and S. Ponnusankar *

Department of Pharmacy Practice, JSS College of Pharmacy, Ooty, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.11(2).535-45

535-545

3949

1804

20.

PATIENT- REPORTED ADVERSE EFFECTS TO ANTI RETROVIRAL DRUGS IN A SPECIALIST HOSPITAL, NORTH WEST NIGERIA

Patients experiencing adverse effects are less likely than those not experiencing it to adhere to treatment. However little is known about the adverse drug reactions to many HIV programme in developing countries, indicating the need for Antiretroviral (ART) safety surveillance. The study is a retrospective analysis of records of adverse reactions by patients initiated on ART. A total of 1870 patie...

I.M. Adebisi*, A.O. Jimoh , E.G. Odoh , A.S. Adebisi 3 S. B. Shittu and Z. Sani

Lecturer II, Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(4).1274-78

1274-1278

3948

1769

11.

SYNTHESIS AND SPECTROSCOPIC STUDIES OF COBALT (II) COMPLEXES WITH NITROGEN- OXYGEN AND NITROGEN SULPHUR DONOR LIGANDS

CoII complexes of ligands pyridine3carboxamide thiosemicarbazone (L1), pyridine 3 carboxamide semicarbazone (L2), pyridine2carboxamide thiosemicarbazone (L3) and pyridine 2 carboxamide semicarbazone (L4) have been synthesized. The ligands were characterized based on elemental analyses, IR, 1HNMR studies while the complexes were characterized by elemental analyses, molar conductance, magnetic momen...

S. Chandra *, S. Raizada and S. Sadwal

Department of Chemistry, Zakir Husain Delhi College, University of Delhi, Jawaharlal Nehru Marg, New Delhi, India.

DOI: 10.13040/IJPSR.0975-8232.5(11).4718-23

4718-4723

3948

1923

30.

PROTECTIVE PROFILE OF HYDNOCARPUS LAURIFOLIA ON STREPTOZOTOCIN INDUCED OXIDATIVE STRESS IN RATS

The present study was aimed to evaluate the anti-oxidative defence system of Hydnocarpus laurifolia in diabetic rats and its potential effect against the β-cell damage induced by oxidative stress. Hydnocarpus laurifolia is a plant which belongs to the family Flacourtiaceae. According to the Indian system of traditional medicine it is used in the treatment of diabetes mellitus. Also literature rev...

P. Sailaja Rao * and G. Krishna Mohan

Department of Pharmacology, Sri Venkateshwara College of Pharmacy & Research centre, Madhapur, Hyderabad, Telangana, India

DOI: 10.13040/IJPSR.0975-8232.8(1).231-35

231-235

3947

1554