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HAEMOVIGILANCE: STEPPING STONE TOWARDS BLOOD SAFETY- INDIAN SCENARIO
Blood transfusion is an important part of various treatment protocols. Blood should be transfused with certain precautions like drug because blood and its constituents have the propensity to cause effects like introduction of donor antigens within the recipient, transfusion reactions or exposure to numerous transfusion-transmitted diseases. Thereby, it is important for the clinicians to remember t...
4008
1828
ANALGESIC POTENTIAL OF HYDROGELS OF SILVER NANOPARTICLES USING AQUEOUS EXTRACT OF SARACA INDICA BARK
The present study reports analgesic potential of hydrogels of silver nanoparticles using Saraca indica bark extract makes a fast and convenient method for the synthesis of silver nanoparticles with the aid of microwave. The synthesized nanoparticles were characterized using UV-visible (UV-vis) spectrophotometer, Transmission electron microscopy (TEM), X-ray diffraction (XRD) and Fourier transform ...
4007
1914
VARIATION IN MEMBRANE ELECTROCHEMICAL POTENTIAL OF PLASMODIUM INFECTED ERYTHROCYTES
Membrane electrochemical potential or zeta potential (ZP) is a feature of the molecular profile of the cell membrane and the two-dimensional arrangement of its charge-bearing molecules. Plasmodium species, the causative agents of malaria, are intracellular parasites that remodel host erythrocytes by expressing their own proteins on erythrocyte membranes. In the present study the variation in the Z...
4007
1435
EVALUATION OF BIOACTIVE COMPOUNDS AND ANTIOXIDANT ACTIVITY OF SOME WILD FRUITS BY IN-VITRO ASSAYS
The present study aimed to evaluate bioactive compounds and total antioxidant activity of differentfruits viz Phyllanthus emblica, Limonia acidissima, Syzygium cumini, Artocarpus hirsutus, Carissa congesta, Anacardium occidentale. Phytochemical study confirms the presence of carbohydrates, proteins, amino acids, cardiac glycosides, steroids, terpenoids and flavonoids in all the fruit extract. Asco...
4006
1867
IMMOBILIZATION OF TANNIN ACYL HYDROLASE FROM ASPERGILLUS NIGER
Tannin acyl hydrolase, commonly referred to as tannase (E.C. 3.1.1.20), an inducible extra-cellular enzyme produced by a number of animals, plants and microbes. In this investigation, tannase production under solid-state fermentation by using Aspergillus niger and the waste residue of cashew husk was used as substrate for obtaining the desired fermented product. After termination of fermentation g...
4006
1623
APPLICATION OF ELECTRON DENSITY AND MOLAR VOLUME AS DESCRIPTORS IN QSAR STUDY OF THE ANTIOXIDANT ACTIVITY OF FLAVONOIDS
QSAR study of lipid peroxidation (LPO) inhibitory activity of 18 flavonoids belonging to four classes namely flavones, isoflavones, flavonols and flavanones has been made with the help of PM3 calculations and geometry optimizations using CAChe software. Quantum-chemical descriptors were calculated by the same software using MOPAC 2002 engine. Two quantum-chemical descriptors, molar volume (M.V.) a...
4005
1753
A STUDY OF ETHNOMEDICINAL PLANT DIVERSITY OF SACRED NATURAL SITES OF PANCHKOSHI PILGRIMAGE OF VARANASI, UTTAR PRADESH INDIA
Introduction: Medicinal plants have always played a major role in primary health care system since time immemorial. Sacred natural sites is the prime place to encompass large medicinal plant with wide range of natural resources. It potentially conserves plant biodiversity with inclusion of sacred places and sacred water bodies. Apart from social and religious importance it, regulate air and water ...
4005
1572
NON DESTRUCTIVE METHOD FOR GENE AND DRUG DELIVERY IN LIVING CELL
Gene transfer represents a relatively new way for the treatment of rare genetic disorders by changing the expression of a person's genes. Electroporation is a mechanical method of gene transfer used to introduce polar molecules such as DNA, RNA and Peptides (Heparin, Insulin) into a host cell through the cell membrane. In this procedure, a large electric pulse temporarily disturbs the phospholipid...
4004
1897
IN VITRO ANTHELMINTIC ACTIVITY OF DIFFERENT EXTRACTS OF ROOT OF CARISSA SPINARUM
Modern medicines are gaining less attention due to their limited availability and affordability in human intestinal helminthesis. Thus, most of the world’s population depends to a greater extent on traditional medical remedies. Carissa spinarum, Linn. (Apocynaceae) is a small spinous, evergreen shrub growing throughout India in dry regions. Further, C. spinarum roots are traditionally used for t...
4004
1538
SCHIFF BASES DERIVED FROM 2-HYDROXY AND 2- METHOXY NAPHTHALDEHYDE: EXPLORATION OF IN SILICO DOCKING, DNA CLEAVAGE, ANTIBACTERIAL ACTIVITIES AND SAR
Antibacterial activities, molecular docking and DNA cleavage activities of five structurally related Schiff bases [L3 (a), L3 (b), L3 (c) L3 (d) and L3 (e)] were performed and their structure activity relationship was studied. Antibacterial activities of these compounds against gram-negative and gram-positive bacteria were evaluated by using well diffusion method and the compound L3 (c); 1-[(E)-(4...
4004
1590