Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
EFFECT OF METOPROLOL AND ATORVASTATIN ON OXIDATIVE STRESS IN SOUTH INDIAN CARDIOVASCULAR PATIENTS
Over production of oxygen free radicals, which is mainly mediated by super oxide, occurs in human atherosclerosis. Metoprolol and atorvastatin are the drugs which found to be more prescribed drugs for cardiovascular patients. In the present study, an attempt has been made to evaluate the levels of serum Glutathione, Total anti-oxidant status, lipid peroxidation (malondialdehide) and liver funct...
4493
1586
PENETRATION OF DICLOFENAC FROM NOVEL QUICK PENETRATING SOLUTION. A COMPARATIVE SCINTIGRAPHY STUDY WITH GEL
Topical NSAIDs do not effectively cross the skin due to barrier of stratum corneum. The aim of the study was to evaluate penetration of diclofenac from a novel quick penetrating solution (QPS) and conventional gel prepared using Tc-99 m labeled diclofenac. The study was conducted in 16 healthy subjects, divided in 4 groups, each with 4 subjects. In first three groups, the applications were made on...
8084
2518
TOXICOLOGICAL EFFECT OF MALLASINDURA (MSL) ON LIVER FUNCTION PARAMETERS OF RAT PLASMA AFTER CHRONIC ADMINISTRATION
Mallasindura (MSL), a widely used ayurvedic preparation is used for the treatment of bronchial asthma. It contains rasa –mercury, Rasakarpura -mercurial compound, Bali –purified and processed sulphur and Malla-purified arsenic oxide with herbal juices. The liver function parameters of rat plasma were studied after chronic administration of MSL. The animals used to conduct this experiment wer...
4188
1461
ANALYSIS OF MOLECULAR INTERACTION IN TRAMADOL DRUG WITH ALCOHOLS UNDER ULTRASONIC TECHNIQUE AT TEMPERATURE T= 278.15 K
The prime aim of this research paper is to find out the various kinds of intermolecular interactions in the alcoholic tramadol below the room temperature. Study of molecular interaction in the mixture of alcohols namely ethanol,1-propanol,1-butanol with tramadol drug at T = 278.15 K have been examined under the ultrasonic technique at 2MHz. Ultrasonic data of drug solutions has been evaluated at v...
3756
1642
ELECTROCHEMICAL BEHAVIOR AND ANALYSIS OF KETAMINE IN PHARMACEUTICAL FORMULATIONS BY VOLTAMMETRIC TECHNIQUES
The electrochemical behavior of Ketamine is studied by employing D.C. Polorography (DCP), Cyclic Voltammetry (CV) and Differential Pulse Polarography (DPP) in universal buffers of pH ranging from 2.0-12.0. The kinetic parameters, such as transfer coefficients, diffusion coefficients and heterogeneous forward rate constant values were evaluated by employing these techniques. Differential Pulse Pola...
4196
1935
STUDY OF ANTIDEPRESSANT ACTIVITY OF CHRONIC ADMINISTRATION OF TRAMADOL AND WHEN IT IS CO-ADMINISTERED WITH FLUOXETINE IN LOW DOSES IN SWISS ALBINO MICE USING DESPAIR SWIM TEST
Objective- To evaluate the antidepressant activity of chronic administration of Tramadol alone and when combined with Fluoxetine in low doses in albino mice. Methods- The antidepressant effect was determined by recording the immobility time in Despair Swim Test. The mice were randomized into seven groups, with six mice in each group. Group 1 mice were given normal saline (10 ml/kg) which served as...
3796
1575
PHARMACOGNOSTICAL STUDIES ON MESUA FERREA, CARICA PAPAYA, ASIMUM SANCTUM AND TRIBULUS TERRESTRIS. IN RAYALASEEMA, A.P.
The Present paper deals with the pharmacognostical studies on Mesua ferrea (Flowers), Carica The Present paper deals with the pharmacognostical studies on Mesua ferrea (Flowers), Carica papaya (Seeds), Asimum sanctum (Leafs) and Tribulus terrestris (Leafs). Fluorescence analysis has been performed and physicochemical characters such as ash values and extractive values have been performed. Prelimin...
5114
1812
STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF DOXYCYCLINE MONOHYDRATE AND ORNIDAZOLE IN BULK AND PHARMACEUTICAL DOSAGE FORM
A simple, rapid, precise, cost effective, stability indicating RP-HPLC method has been developed and validated for the simultaneous estimation of Doxycycline monohydrate (DOXM) and Ornidazole (ORN) in Bulk and pharmaceutical dosage form. The chromatographic separation was achieved on Hypersil BDS C18 column (250mm ×4.6mm, 5μm) using a mobile phase consisting of Buffer : Acetonitrile (55:45 v/v...
3807
3140
OPTIMIZATION OF INFLUENZA A AND B VIRUSES CULTIVATION CONDITIONS FOR PREPARATION OF TRIVALENT SEASONAL INFLUENZA SPLIT VACCINE
This article presents the results of studies on determination of optimal parameters of recombinant strains A/NYMC X-217 (H3N2) and B/NYMC BX-49 of influenza virus cultivation in chicken embryos. It is found that a maximum virus accumulation is formed under the following cultivation conditions: age of chicken embryos is 9-11 days in case of inoculation of the allantoic cavity, inoculated virus dose...
3914
1393
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF NEW BAYLIS-HILLMAN DERIVED NITRO METHYLENE IMIDAZOLE DERIVATIVES AS INSECTICIDAL AGENTS
A series of Baylis-Hillman derived N-cinnamyl substituted nitro methylene imidazole derivatives 4a-swere synthesizedfrom Baylis-Hillman acetates and nitro methylene imidazole compoundsand characterised by 1H NMR, IR, Mass and HRMS spectroscopy. Their insecticidal activities were evaluated against T. Castaneum and compared with a standard insecticide Permethrane. Preliminary biological activity tes...
3713
2077