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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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36.

SYNTHESIS AND IN-VITRO ANTIPROLIFERATIVE ACTIVITY OF SUBSTITUTED-2, 3-DIMETHYL-N-(3-(4-PHENYL PIPERAZIN-1-YL) PROPYL)-6, 7-DIHYDRO-5H-BENZO [7] ANNULENE-8-CARBOXYLIC ACIDS

Benzosuberones and phenylpiperazinyl moieties are important heterocyclic compounds which constitute many biological activities which include anti bacterial, anti fungal, anti inflammatory, antioxidant, antitubercular and anti cancer activities. A novel series of 2,3-dimethyl-N-(3-(4-phenyl piperazin-1-yl)propyl)-6,7-dihydro-5H-benzo[7] annulene-8-carboxylic acids (5a-e) have been synthesized in go...

K. Vijay * and C. B. P. Devi

Department of Chemistry, University College of Pharmaceutical Sciences, Acharya Nagarjuna University, Nagarjuna Nagar, Guntur, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.9(10).4343-48

4343-4348

2862

1520

50.

EVALUATION OF PHYTOCONSTITUENTS, FT-IR ANALYSIS, TOTAL PHENOLIC, FLAVONOID CONTENTS, IN-VITRO ANTIBACTERIAL AND ANTIOXIDANT STUDIES OF ETHANOLIC ROOT EXTRACT OF MILLETTIA PINNATA

This research work presents the phytochemical and FTIR analysis, total phenolic, and flavonoid quantification, and evaluation of in-vitro antibacterial and antioxidant activity of ethanolic root extract of Millettia pinnata. Ethanolic root extract was subjected to the phytochemical and FTIR spectrum analysis. Total phenolic and flavonoid contents were quantitatively determined by Colorimeter. The ...

R. K. Banoth *, S. Shaik, T. Dumpala and P. Yadav

Institute of Pharmaceutical Technology, Sri Padmavati Mahila Visvavidyalayam (Women’s University), Tirupati, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(5).2396-02

2396-2402

2862

1559

70.

PHARMACOGNOSTICAL STUDY OF THE AUTHENTICITY OF MORINGA OLEIFERA LEAVES

Moringa oleifera is widely used in Asia and Africa as an anti-inflammatory, anti-diabetic, and cold agent. However, there are no Moringa medicines on the Russian pharmaceutical market; therefore, it is of interest for research as a promising source of raw materials and introduction to the State Pharmacopoeia of Russian Federation. This study was conducted to compare the characteristics of the auth...

I. V. Gravel *, H. N. Amutenya and U. K. Upadhyaya

Department of Pharmaceutical Science, Institute of Pharmacy, Sechenov First Moscow State Medical University, Moscow, Russia.

DOI: 10.13040/IJPSR.0975-8232.12(2).1272-76

1272-1276

2862

1351

45.

NANOSPONGES AS NOVEL CARRIER FOR TOPICAL DELIVERY OF LULICONAZOLE -AN ANTIFUNGAL DRUG

The main goal of this work is to formulate nanosponges and access its suitability to deliver Luliconazole for topical application, to improve its therapeutic effect, better dispersion and good storage. Nanosponges are water-soluble, which does not mean that molecules are chemically decomposed in water but that nanosponge particles are mixed with water and used as a carrier fluid. Compared with tra...

B. S. Wakure *, M. A. Salunke, P. T. Mane, S. R. Awale, R. D. Shinde and S. S. Eklinge

Vilasrao Deshmukh Foundation, Group of Institutions, VDF School of Pharmacy, Latur, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(10).5570-83

5570-5583

2862

2295

1.

WOUND HEALING PERSPECTIVES OF PROMISING HERBAL RESOURCES: A REVIEW

A wound is described as a break in a tissue's cellular and anatomic continuity. A wound is a cellular, anatomical, and functional disturbance of living tissue induced by physical, chemical, electrical, or microbiological threats to the tissue. Wound healing is a multi-step process involving injured tissue regeneration or restoration. The typical wound-healing response is a coordinated series of pr...

Dinesh Kumar * and Vivek

Department of Pharmaceutical Sciences, Shri Jagdishprasad Jhabarmal Tibrewala University, Jhunjhunu, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.14(5).2011-29

2011-2029

2859

1420

48.

ISOLATION AND CHARACTERIZATION OF BIOFILM FORMING MULTIPLE DRUG-RESISTANT BACTERIA FROM PATIENTS INFECTED WITH UTI

Biofilms are protective organic extracellular polymeric substances secreted by a microbial population which prevents the penetration of antimicrobial substances such as antibiotics. The existence of biofilms has become a significant problem in the case of infections as well as industrial processes. Although, biofilms may act as an advantage to the microbial community, they are found to cause food ...

Y. Rajkumar, N. Asma and P. Shlini *

Department of Chemistry (PG Biochemistry), Mount Carmel College, Autonomous, Bengaluru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(4).1922-28

1922-1928

2858

1329

41.

STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR DETERMINATION OF RELATED SUBSTANCE IN VENLAFAXINE HYDROCHLORIDE TABLETS

Recently, several methods have been developed for the determination of drugs and their impurities products by Reverse Phase-High Performance Liquid chromatography (RP-HPLC). The present paper describes highly specific, linear, precise, rugged, accurate, robust, and stability, indicating the RP-HPLC method for the determination of related substances present in Venlafaxine tablets as per ICH guideli...

A. Ajitha * and G. S. Rani

Department of Pharmaceutical Analysis, CMR College of Pharmacy, Kandlakoya, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.11(8).3923-29

3923-3929

2858

1794

17.

EVALUATION OF ANTIBACTERIAL ACTIVITY OF PENTABARK KASHAYA AGAINST SELECTED BACTERIAL STRAINS CAUSING WOUND INFECTION: IN-VITRO STUDY

Background: Wound infection occurs when one or more organisms invade the wound. Nosocomial infections are the most common hospital acquired infections responsible for mortality and morbidity. Multidrug resistance against bacterial strains is the most serious emerging situation in worldwide, warranting the search for other alternatives. In this regard Pentabark kashaya was developed which contains ...

M. Mandiwalar *, S. S. Pradeep, R. R. Hiremath and R. Killedar

Department of Shalya Tantra, KAHER’S Shri B. M. Kankanawadi Ayurveda Mahavidhyalaya Shahapur, Belagavi, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3687-92

3687-3692

2858

1277

14.

FRESH JUICE OF DRYNARIA QUERCIFOLIA RHIZOME FOR THE MANAGEMENT OF ARTHRITIS

Drynaria quercifolia rhizome (DQR) ethnomedicinal information shows the traditional usage of this rhizome for the treatment of body and joint pain, diarrhoea, typhoid, cholera, and skin diseases. The fresh juice of rhizome is still being consumed as an energy drink by tribes and localities of Tamil Nadu and Kerala. However, no investigations have been carried out to claim the anti-arthritic activi...

U. M. Dhanalekshmi, B. Ramya, T. Gowri and R. Srinivasan *

Organic and Bio Organic Chemistry Division, CLRI, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.12(3).1465-73

1465-1473

2857

1500

22.

THE POTENTIAL PROTECTIVE EFFECT OF ROASTED DATE PALM CAKE EXTRACTS (PHOENIX DACTYLIFERA L.) AGAINST NICKEL CHLORIDE-INDUCED INFERTILITY IN MALE MICE

The powder date palm cake is sold in coffee and confectionary shops in the central region of the Kingdom of Saudi Arabia, where it is used as a hot drink in the form of decoction. It is alleged by users in the local community in Saudi Arabia to improve fertility. The date palm cake is the roasted grounded seeds of the date palm (Phoenix dactylifera L.). The objective of this study is to evaluate t...

S. E. M. Eltom *, M. A. Mobark, M. S. Al-Omer, H. A. Mohammed, E. M. E. Agabein, M. H. Alqambar and M. Alhawsawi

Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Qassim University, KSA.

DOI: 10.13040/IJPSR.0975-8232.10(11).4988-94

4988-4994

2856

1146