Pages Menu
TwitterRssFacebookWhatsapplinkedin
ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

Categories Menu

Most Popular

 
Title
Views
PDF
Cited
36.

A RANDOMIZED SINGLE BLIND PLACEBO CONTROLLED CLINICAL STUDY TO EVALUATE EFFICACY OF AMALAKI (EMBLICA OFFICINALIS) EXTRACT CAPSULE ON ACNE VULGARIS ALONG WITH ITS ANTI-OXIDANT PROPERTY

Background and Objectives: Acne vulgaris is a chronic skin infection affecting the majority of teenagers and adolescents. It is a disease that affects almost 80% of individuals. Acne, by definition, is multi-factorial chronic inflammatory disease of the Pilosebaceous unit. Nowadays, herbal formulations are gaining popularity in the treatment of various diseases. By considering this fact, the prese...

G. Patel *, R. Sorake and N. Pai

K. Patel Phyto Extractions Pvt. Ltd. 507, B Wing, Eureka Tower, Mind Space, Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(7).3832-38

3832-3838

2880

1268

35.

IN-SILICO MOLECULAR DOCKING ANALYSIS OF ISOLATED HOMOISOFLAVANONES FROM BULBS OF LEDABOURIA REVOLUTA AS GABAA RECEPTOR INHIBITORS

γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the vertebrate central nervous system (CNS); it activates the GABAA receptors that play a role in epilepsy. Targeting GABAA receptors through specific enhancement of neuronal inhibition involving GABA can be a better mechanism for identification of novel antiepileptic drugs. In this report, screening of novel isolated homoisof...

B. S. Veena and E. Sujatha *

Department of Botany, University College of Science, Osmania University, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.10(9).4315-21

4315-4321

2878

1378

36.

IN-VITRO EVALUATION OF ANTIOXIDANT ACTIVITIES OF OLDENLANDIA CORYMBOSA L. (SYN. HEDYOTIS CORYMBOSA) FRACTIONATED EXTRACTS IN VARIOUS SOLVENTS

Antioxidants are the substance having the potential to quench free radicals and significantly delay or inhibit oxidation of the substrate, thus protect biological systems against potentially harmful effects of free radicals; in low concentrations. The present study was aimed to evaluate the in-vitro antioxidant activity of Oldenlandia corymbosa L., a locally available medicinal plant of Assam, use...

G. K. Das and R. Bharali *

Department of Biotechnology, Gauhati University, Guwahati, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.11(6).2840-50

2840-2850

2878

1653

17.

A MATHEMATICAL APPROACH OF EXPLORATION TOWARDS EXTREME RISK FACTOR IN CANCER OF OPTIMAL CONDITION

The aim of this present investigation is to identify the most important risk factor for cancer by means of a mathematical model. The study begins with considering some types of cancer viz. breast, colorectum as well as lung and bronchus cancer as most of the cancer patients suffer from these types of cancers. Teaching-Learning-Based Optimization technique is applied to sorting out the most lethal ...

P. Majumder *, A. K. Saha and M. Majumder

Department of Mathematics, National Institute of Technology, Agartala, Barjala, Jirania, Tripura, India.

DOI: 10.13040/IJPSR.0975-8232.9(9).3732-42

3732-3742

2877

1323

25.

DESIGN, SYNTHESIS AND COMPARATIVE PHARMACOLOGICAL ASSESSMENT OF NOVEL FLUOROQUINOLONE DERIVATIVES

One of the proposed groupings of the fluoroquinolones describes the excellent broad-spectrum activity forms an invaluable part of the present anti-infective armory of the clinicians. The fluoroquinolones are most significant weapons can be credited for saving more human lives than any other area of medicinal therapy. In this current research segment, the novel C-3 substituted fluoroquinolone scaff...

P. P. Majalekar *, P. K. Shirote, V. Nalawade and P. Shelake

Department of Pharmaceutical Chemistry, Appasaheb Birnale College of Pharmacy, Sangli, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.10(8).3735-40

3735-3740

2877

1603

4.

AN UPDATE ON BIOLEACHING TECHNOLOGY: IRON BACTERIA AS A SOURCE OF OXIDIZING IRON TRACES FROM WATER SAMPLES

The removal of metals by the use of microbes is known as bioleaching in terms of oxidation or degradation of metal from complex raw materials or depots. Such microbial oxidation or bio-removal occurs in terms of sulphur degradation and oxidation (for example, sulphur oxidation, iron oxidation etc.). This process is thus known as bioleaching, which is related to the all metal oxidation processes li...

U. Rani *, S. Gupta and V. Kumar

Department of Biotechnology, Himalayan School of Biosciences, Swami Rama Himalayan University, Jolly Grant, Dehradun, Uttarakhand, India.

DOI: 10.13040/IJPSR.0975-8232.12(2).744-53

744-753

2875

1427

51.

EVALUATION OF ANTIDIABETIC ACTIVITY OF WITHANIA COAGULANS L. DUNAL

The present study estimated the antidiabetic activity of methanolic extract of plant fruits of plant Withania coagulans L. Dunal. Withania coagulans (family Solanaceae) is commonly known as “Paneer ke phool” in Hindi and “Indian cheese maker” or “Vegetable rennet” in English, distributed in drier parts of India. The primary aim of this study was to confirm antidiabetic action of Withan...

M. D. Rageeb *, M. D. Usman and N. G. Bhat

Department of Pharmacognosy, Smt. Sharadchandrika Suresh Patil College of Pharmacy, Chopda, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.14(2).981-87

981-987

2875

1482

10.

SPECTROPHOTOMETRIC ANALYSIS OF BOVINE SERUM ALBUMIN IN PRESENCE OF 1-(4-AMINOPHENYL)-3-PHENYLPROP-2-EN-1-ONES

Proteins, which are soluble under normal physiological conditions, sometimes form insoluble aggregates with serious medical implications. Bovine serum albumin (BSA), a structural analogue of human serum albumin. Bovine Serum Albumin (BSA) has been used as a carrier, and stabilizing agent, for insoluble fatty acids. The chemistry of chalcone has been recognized as a significant field of study. An i...

S. Garg, M. Singh and N. Raghav*

Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2657-61

2657-2661

2874

1571

50.

DESIGN, SYNTHESIS AND MOLECULAR DOCKING STUDIES ON NOVEL CINNOLINE DERIVATIVES AS POTENTIAL ANTITUBERCULOSIS AGENTS

The emerging need for the multidrug regimen of M. tuberculosis strains urged us to synthesize novice and potent anti-tubercular medicaments. Our interest in this work had afforded a series of novice cinnolines as a new structural category of antituberculosis agents. All 14 compounds were synthesized using the appropriate scheme, two-step reactions with the high yielding product. The newly synthesi...

M. P. Evangelin *, P. P. Kumar and K. Balamurugan

Department of Pharmacy, Annamalai University, Chidambaram, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.11(4).1898-05

1898-1905

2873

1605

39.

DEVELOPMENT AND VALIDATION OF RP-HPLC FOR SIMULTANEOUS ESTIMATION OF PREGABALIN AND ETORICOXIB IN PHARMACEUTICAL TABLET DOSAGE FORM

A simple, precise, rapid, linear and economical RP-HPLC method was developed and validated for simultaneous estimation of Pregabalin and Etoricoxib in pharmaceutical tablet dosage form. The determination was performed on Phenomenex C18 (250 mm × 4.6 mm, ID, 5µ) column at 30 ºC temperature using a mobile phase Acetonitrile: Water (55:45 %v/v) at a flow rate of 0.8 ml/min was employed. The RP-HPL...

M. B. Karanjkar

Department of Quality Assurance Techniques, S.V.P.M. College of Pharmacy Malegaon (BK), Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.13(2).872-79

872-879

2872

1389