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TOXIC IMPACT OF λ- CYHALOTHRIN ON DNA AND RNA CONTENTS OF THE FISH CTENOPHARYNGODON IDELLA
The synthetic pyrethroids used in agriculture also absorb rapidly via different routes and slowly accumulate into various vital tissues and cause adverse effects on the health status of animals. It leads to produce a number of biochemical changes at the level of nucleic acids. The freshwater fish Ctenopharyn godonidella was exposed to sublethal concentrations (1/10th of LC50 value) of λ- cyhalo...
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453
SOLUBILITY ENHANCEMENT AND OPTIMIZATION OF VARIOUS VARIABLES OF FAST DISINTEGRATING TABLETS OF LERCANIDIPINE HYDROCHLORIDE USING CENTRAL COMPOSITE DESIGN
The oral route of drug administration is the most common and preferred method of delivery due to convenience and ease of ingestion, but it is problematic if the drug is poorly soluble. Sufficient drug absorption, reproducible bioavailability and pharmacokinetic profile of orally administered drug substances are highly dependent on the solubility of that compound in an aqueous medium. Also, the the...
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670
IN VITRO AND IN VIVO EVALUATION OF POLY (CAPROLACTONE FUMARATE) NANOPARTICLES
Retraction Note : Shokri N, Azizi E, Akbari Javar H, Fouladdel Sh, Khalaj A, Dinarvand R. In vitro and in vivo evaluation of poly (caprolactone fumarate) nanoparticles. International Journal of Pharmaceutical Sciences and Research. 2012; 3(9):3106-3115. It has come to the attention of the IJPSR Editors that there are substantial overlaps between the text of the above article and the foll...
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DESIGN AND CHARACTERIZATION OF SOME NEW NON-SYMMETRIC SUBSTITUTED TRIAZINES AND TRIAZINE DERIVATIVES
Attempts were made to carry out the laboratory synthesis of non-symmetric mono-, di- and tri- substituted 1, 3, 5-triazines by the action of the electron-donating substituent on 2, 4, 6-trichloro-1, 3, 5-triazines by aromatic nucleophilic substitution reaction mechanism (SNAr reaction) by temperature controlled. The introduction of the amino group (-NH-), ether (-O-) and thiol (-S-) Linker Bridge ...
1506
1254
DEVELOPMENT OF HERBAL NIOSOMES FOR WOUND HEALING
Traditionally Psidum guajava has been used for the treatment of several kinds of disorders. The component quercetin a flavonoid that is present in the guava leaves, is responsible of having wound healing properties, so the aim and objective of the study was to Develop Herbal loaded Niosomes for the treatment of Wound Healing. To enhance the transport and efficacy of many materials through stratum ...
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582
UPLC STABILITY INDICATING METHOD FOR SIMULTANEOUS ESTIMATION OF GLECAPREVIR AND PIBRENTASVIR
A forced stability-indicating method for simultaneous estimation of glecaprevir and pibrentasvir by Ultra Performance Liquid Chromatography (UPLC) was developed and validated. The separation was done on column BEH C18 50 × 2.1mm 1.7m which was maintained at 30 °C, eluted with isocratic mobile phase and eluents were detected at 260nm. Mobile phase containing Buffer 0.01NKH2PO4: Acetonitrile taken...
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778
EFFICACY OF TWO AYURVEDA REGIMEN IN MILD SCORPION STING: AN OPEN-LABEL, TWO-ARM, CLINICAL TRIAL
Background: Scorpionism is an endemic and highly prevalent public health predicament causing severe cardio or neurotoxic effect. Ayurveda proposes a range of medicinal preparations (internal & external) in the management of Vrishchika Damsha (Scorpion sting). Among them, Hingwadi and Jeerakadi lepa are topical anti-inflammatory medications, and Bilwadi Gutika is a potent vishahara medicine (Al...
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560
AMELIORATION OF DEXTRAN SULPHATE SODIUM INDUCED ULCERATIVE COLITIS IN MICE BY STEM BARK EXTRACT OF TERMINALIA TOMENTOSA
A plethora of herbs have been tested for their activity against ulcerative colitis, a debilitating disease in the group of IBDs. However, a promising adjuvant to conventional therapy remains still at large. Ellagic acid, a polyphenol widely available in berries have shown efficacy against ulcerative colitis in preclinical models. Owing to its high content of ellagic acid and its analogs, the stem ...
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612
INFLUENCE OF PIOGLITAZONE ON IMMUNOMODULATORY ACTIVITY OF AZATHIOPRINE IN RODENT MODELS
The present study was designed to investigate the antioxidant and immunomodulatory activity of Azathioprine-Pioglitazone combination therapy to check whether it has added on benefit over monotherapy with Azathioprine or Pioglitazone in rodent models. The test drugs in combination showed better inhibition of free radicals in both H2O2 radical scavenging assay and nitric oxide scavenging assay than ...
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591
DIURETIC ACTIVITY OF HYDROALCOHOLIC EXTRACT OF FRAGARIA ANANASSA FRUIT IN WISTAR ALBINO RATS
Fragaria ananassa fruit are small shrubs belonging to family rosaceae. Fragaria ananassa mainly contains anti-oxidants such as tocopherols, ascorbic acid and b-carotene which are effective against cancer, heart disease and cataracts. The focus of the study was toanalyze the diuretic activity of hydro alcoholic extract of Fragaria ananassa fruit in albino rats. Diuretic activity of hydroalcoholic (...
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566