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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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43.

THE IMPACT OF CARCINOGENIC CHEMICAL USE AMONG CARDAMOM FARMERS AND THE PREVALENCE OF CANCER IN IDUKKI DISTRICT, KERALA

The prevalence of cancer is drastically increasing among cardamom farmers using chemical pesticides in Idukki district. The chemicals, mainly Organochlorine and organophosphates, result in various disease conditions. The main aim of the study was to explore the prevalence of cancer and other disease conditions among farmers and other people who were exposed to chemical pesticides. A community-base...

B. Mishra * and D. Johnson

Department of Pharmacology and Research & Development Cell Nirmala College of Pharmacy, Muvattupuzha, Ernakulam, Kerala, India.

DOI: 10.13040/IJPSR.0975-8232.12(5).2884-91

2884-2891

2300

1040

5.

REVITALIZING RATIONALITY THROUGH PDAA CYCLE-A UNION THERAPY CONCEPT

Medicine has been a noble profession since time immemorial. Many cultures have the view that it is linked with the supernatural deity. The persons were priests in many civilizations. They had high status in Society. They were considered as a medium of communication between the supernatural and were assumed to have powers. In those times, those priests used rituals and follow some religious code of...

K. Kala * and R. K. Sodhi

IK Gujral PTU (IK Gujral Punjab Technical University, Jalandhar, Punjab, India.

DOI: 10.13040/IJPSR.0975-8232.11(12).5987-94

5987-5994

2298

1019

59.

DETECTION OF B. ABORTUS S19 ON UTERINE RAT (RATTUS NORVEGICUS) WITH IMMUNOHISTOCHEMICAL METHOD

Objective: Brucellosis in humans is the most common zoonotic infection in the world. Brucellosis can be prevented by vaccination but no effective vaccines are known for prevention of human brucellosis and minimal impact of animal brucellosis. Outer membrane proteins (OMPs) of Brucella sp. have been the focus of vaccine development and the diagnosis of brucellosis. Methods: The pathogenesis study o...

F. Purnamawati *, S. Santoso and Aulanni’am

Biomedical Science Master Program, Medical Faculty, Universitas of Brawijaya Malang, Indonesia.

DOI: 10.13040/IJPSR.0975-8232.9(9).4021-28

4021-4028

2295

1103

30.

INDOLE 1,2,3,4-TETRAHYDROPYRIMIDINONE: SYNTHESIS, CHARACTERIZATION AND IT’S BIOLOGICAL APPLICATIONS

The present research work involves the use of exclusively and commercially available indole-3-carbaldehyde as a starting material to synthesize novel pyrimidine analogues. The synthesis of series of indole and pyrimidine containing N-substituted-4-(1H-indol-3-yl)-6-methyl-2-oxo-1, 2, 3, 4-tetrahydro-pyrimidine-5-carbohydrazide U(1-10) has been done by using principle of Biginelli condensation reac...

G. S. Mhaske *, R. H. Khiste, S. A. Shinde and S. A. Jadhav

Department of Pharmaceutical Chemistry, Marathwada Mitra Mandal’s College of Pharmacy, Thergaon, Pune, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.12(2).963-72

963-972

2293

1204

46.

NANOTECHNOLOGY BASED ORAL FORMULATIONS OF TOLBUTAMIDE BY USING BIODEGRADABLE POLYMER

The present study concerns the development, characterization, and optimization of nanoparticulate oral formulations of Tolbutamide using poly (ԑ-caprolactone) which is a biodegradable polymer. Emulsion Solvent Evaporation technique was used for preparation of drug-loaded polymeric nanoparticles. This research was carried out to improve the therapeutic efficacy of tolbutamide by increasing its bio...

N. Singh, P. K. Verma * and S. Nanda

Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.10(12).5599-05

5599-5605

2292

959

33.

EFFECT OF GARLIC AND GINGER AQUEOUS EXTRACT ON MITOTIC INDEX OF ONION ROOT TIPS GROWN IN PESTICIDE CONTAINING WATER

Since ancient times, herbal knowledge has been used in the field of health care by different cultures. Ginger and garlic are important herbs that have covered a wide role in various health ailments like kidney and heart diseases. Also, they are considered to be potential against suppressing toxicity. The present study was conducted to evaluate the toxicity suppressing capability of these two herbs...

K. Das, J. Gogoi * and P. Dutta

Faculty of Sciences (Biochemistry), Assam down town University, Panikhaiti, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.12(2).988-90

988-990

2291

835

53.

HAEMOTOXICITY OF LEAD (Pb) ON THE BLOOD PARAMETERS OF FRESH WATER TELEOST HETEROPNEUSTES FOSSILIS (BLOCH)

Blood parameters are important indicators for assessing the health status of living organisms subject to changing environment. Blood parameters (Hb%, TEC, TLC, ESR, PCV, MCH, and MCV) of Heteropneustes fossilis exposed to lead were investigated at different time intervals. Acclimatized specimens were divided into four groups: Group-A (Control), Group-B (2.25 ppm), Group-C (2.65 ppm), Group-D (2.85...

V. K. Verma, N. Gupta * and D. K. Gupta

Chhatrapati Shahu Ji Maharaj University, Kanpur, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(3).1444-51

1444-1451

2290

842

20.

MOLECULAR VERSUS CONVENTIONAL TECHNIQUES FOR THE DETECTION OF STAPHYLOCOCCUS AUREUS, PSEUDOMONAS AERUGINOSA AND CANDIDA ALBICANS IN NON-STERILE PHARMACEUTICAL PREPARATIONS

Notable progress has been made in methods that encourage the use of PCR as a rapid and accurate tool in quality evaluation of pharmaceuticals. In this study, monoplex and multiplex PCR based assays were developed and compared with standard conventional methods for rapid detection of three specified topical indicator pathogens, Pseudomonas aeruginosa, Staphylococcus aureus, and Candida albicans, in...

R. S. El-Houssieny, M. M. Aboulwafa *, W. F. Elkhatib and N. A. Hassouna

Department of Microbiology and Immunology, Faculty of Pharmacy, Ain Shams University, Cairo, Egypt.

DOI: 10.13040/IJPSR.0975-8232.11(9).4279-92

4279-4292

2290

886

25.

TO EVALUATE THE USE AND SAFETY OF BLOOD THINNING AGENTS IN TERTIARY CARE HOSPITAL

Objective: To ensure the basic principles of drug utilization and the use and safety of blood thinning agents in tertiary care hospital. Experimental design: The study included 224 patients’ and was conducted in a tertiary care hospital and we were focused on to find out the drug-drug interactions of anticoagulants, antiplatelet, and thrombolytic agents, to study the major area involvement for b...

S. S. Jokandan *, D. K. Jha and T. N. Swamy

Department of Pharm D, Karnataka College of Pharmacy, Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(7).3332-39

3332-3339

2289

882

43.

DEVELOPMENT AND EVALUATION OF CANDESARTAN CILEXETIL TABLETS USING CRYSTAL AGGREGATES PREPARED BY POLYMER ENRICHED BRIDGING LIQUID

The main objective of the study was to formulate tablets of Candesartan cilexetil using the crystal agglomerates for the enhancement in flow properties and solubility. The crystal agglomerates were prepared by polymer enriched bridging liquid (PEBL) technique. The process requires three solvent systems, the good solvent for the drug, the bad solvent and the bridging liquid. The hydrophilic polymer...

K. Manoj, P. Seenivasan *, K. Arul and M. S. Kumar

Faculty of Pharmacy, Sri Ramachandra Institute of Higher Education and Research, Porur, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(12).5579-86

5579-5586

2289

1168