Most Popular
PHYSICOCHEMICAL CHARACTERIZATION OF 99mTECHNITIUM – LUTEOLIN AS RADIOPHARMACEUTICAL PREPARATION FOR ANTIOXIDANT COMPOUND
The objective of this study was to formulate luteolin with radioisotope Technetium-99m (99mTc) to be 99mTc-Luteolin as an antioxidant compound. After optimization, this radiopharmaceutical preparation should be examined for its physicochemical characteristics, such as radiochemical purity, stability, lipophilicity, protein plasma binding, electronic charge, and stability test. The formulation was ...
2907
1126
DELAYED POST-OPERATIVE SURGICAL SITE INFECTION: SOURCE AND INVESTIGATION OF CAUSATIVE AGENT
About 70 middle aged (20 - 45 years) patients, including 40 males and 30 females, operated at Base Military Hospital, Meerut Cantonment Board, Meerut (India) developed typical symptoms of pus formation at surgical sites and opening of sutures after 30 - 45 days. To investigate the causative pathogen and source of infection, various samples were collected from wounds and various sites of Operation ...
2906
1376
MEASUREMENT OF NATURAL RADIOACTIVITY IN BUILDING MATERIALS SAMPLES BY USING (HPGe) SYSTEM
In the present work, we have measured natural radioactivity in twelve building materials samples for four kinds (Brick, cement, gypsum and sand) obtained from some Iraqi governorates by using High Purity Germanium (HPGe) radiation detectors system. The results of measurements have shown that the average values specific activity concentrations for 238U, 232Th and 40K which were equal to (24.236 ± ...
2906
1462
DESIGN AND DEVELOPMENT OF SUPERPOROUS HYDROGEL OF AN ANTIHYPER-TENSIVE DRUG FOR GASTRORETENTIVE DRUG DELIVERY
Superporous hydrogels (SPHs) is originally developed as a novel drug delivery system to retain drugs in the gastric medium by instant swelling on water absorption through open porous structure and maintain their integrity in that harsh environment. Atenolol, an antihypertensive drug with a short half-life, limited bioavailability, unstable nature at basic pH potentiated the need for developing a g...
2905
1253
FABRICATION AND CHARACTERIZATION OF NANOSUSPENSION FORMULATION OF DIOSMIN FOR ENHANCED ORAL DELIVERY
Nanosuspension is a biphasic system consisting of drug particles dispersed in an aqueous surfactant or polymeric solution with a particle size between 10 to 1000 nm. Nanosuspension offers the unique advantage of increasing solubility of the pure drug resulting into faster drug absorption and hence achieving faster maximum plasma concentration. Hence, the aim of this research work was to formulate ...
2905
1721
ANTIASTHMATIC EFFECT OF LEAVES OF EVOLVULUS ALSINOIDES
Evolvulus aslsinoides is being used in traditional medicine for the treatment of severe bronchitis and asthma. So the aim of study was to evaluate antioxidant and antiasthmatic activity of ethanol extract of Evolvulus aslsinoides leaves. The present investigation was undertaken to evaluate the histamine-induced bronchospasm of alcoholic extract of Evolvulus aslsinoides leaves in experimental anim...
2904
1255
USING OF INFORMATIONAL PARAMETERS AS A CRITERION FOR DETERMINING THE EFFECTIVENESS OF BIOSTIMULATION WITH USE OF TISSUE PREPARATIONS
Possibility of use of the informational parameters, which characterize adaptational and regenerative opportunities of organ, as potential criteria for the assessment of biological activity of tissue preparations, is investigated in this research. The influence of tissue preparation «STEMB» on the morphofunctional condition of a liver of rats at experimental toxic damage of organs was studied. Th...
2902
1382
STRUCTURAL ELUCIDATION OF CHITOSAN BASED HETEROCYCLIC COMPOUNDS OF ANTI-MICROBIAL AND ANTI-CANCER ACTIVITY
Schiff bases from chitosan and 5-nitro salicylaldehyde-aniline complexes represented the important structural subject in excess of biologically active molecules, including synthetic. The introduction of 5-nitro salicylaldehyde at C-2 nitrogen position and aniline at C-6 oxygen position of chitosan. The structure-activity relationship (SAR) of the double Schiff based chitosan, synthesized from the ...
2902
1300
FORMULATION DEVELOPMENT AND OPTIMIZATION OF HERBAL IMMEDIATE RELEASE TABLET FOR DENGUE
Dengue is the most rapidly spreading mosquito-borne viral disease in the world. Patients with dengue fever are treated symptomatically. There is no specific allopathic treatment for dengue fever. Traditional medicinal plants have been reported to be useful in the treatment of dengue fever. The development of new anti-dengue products from bioactive compounds is necessary to find an effective treatm...
2901
1455
FORMULATION AND EVALUATION OF CIPROFLOXACIN HYDROCHLORIDE ENCAPSULATED LIPOSOMAL HYDROGEL FOR DERMAL ADMINISTRATION
The present work aims to formulation and characterization of a topical liposomal gel for ciprofloxacin hydrochloride. The drug lipid interaction studies were carried out by FTIR analysis, X-ray diffraction study, and DSC study, and no changes of physicochemical properties of ciprofloxacin were found. The thin-film hydration method was used for the preparation of liposomes consisting of phosphatidy...
2900
2006