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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

A Web of Science - ESCI Indexed Journal
Projected Impact Factor (2019): 1.230 , CiteScore (2017): 0.27

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52.

PHYTONUTRIENTS AND ANTIMICROBIAL ASSAY OF CAT’S TAIL

Herbal medicine plays an important role in rural areas, and various locally produced drugs are still being used as household remedies for different ailments. Acalypha hispida (Euphorbiaceae) is a plant popularly used in pharmaceutical used and as a commercial product. Hence, the need to explore the potential of this plant, especially in the area of traditional medicine and pharmaceutical industrie...

D. Saikia * and B. Parasar

Department of Biotechnology, Kaliabor College, Kuwaritol, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.11(9).4540-49

4540-4549

155

74

48.

EFFECT OF OLANZAPINE ON HYPERTHERMIA IN SEROTONIN SYNDROME MODEL

The serotonin syndrome is a life-threatening adverse drug reaction caused by a significant increase in the concentration of 5-hydroxytryptamine (serotonin) in the central nervous system. The aim of this study was to establish the effects of olanzapine, an antipsychotic drug, on the hyperthermic response in rat experimental serotonin syndrome. In this study, we used an animal model of the serotonin...

R. Nikolov * and G. Bogdanov

Department of Pharmacology and Toxicology, Faculty of Medicine, Medical University, 2 “Zdrave” Sofia, Bulgaria.

DOI: 10.13040/IJPSR.0975-8232.11(9).4509-12

4509-4512

155

89

66.

DEVELOPMENT, OPTIMISATION, AND CHARACTERISATION OF SNEDDS OF ANTI-LIPASE INHIBITOR

Background: Self-Nanoemulsifying Drug Delivery System (SNEDDS) has been employed extensively by the formulation of scientists to tackle the low solubility issues of various drugs and lift the bioavailability profile. But the potential of SNEDDS is not limited to augment the dissolution profile only. Objective: The objective of the study was to develop, optimization, and characterization of SNEDDS ...

A. Vyas *, A. Diwan and R. Sharma

School of Pharmaceutical Sciences, Apeejay Stya University, Gurgaon, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.11(9).4667-75

4667-4675

155

84

64.

A COMPARATIVE STUDY ON PROXIMATE AND MINERAL COMPOSITION OF UNPROCESSED AND PROCESSED UNDERUTILIZED JERUSALEM ARTICHOKE TUBER FLOUR

Jerusalem artichoke is one of the underutilized tuber crops distributed worldwide in temperate areas. It is considered healthy and functional food due to its chemical composition as it contains proteins, mono or poly-unsaturated fatty acids, dietary fibers, vitamins, and minerals. In this present research work, the effect of processing on the proximate and mineral composition of Jerusalem artichok...

D. Gupta * and N. Chaturvedi

Department of Food Science and Nutrition, Banasthali Vidyapith, Tonk, Rajasthan, India.

DOI: 10.13040/IJPSR.0975-8232.11(9).4648-54

4648-4654

154

75

56.

METHODS OF EXTRACTION AND FRACTIONATION OF BIO-ACTIVE COMPONENTS OF MORINDA COREIA FOR ANTI-TUBERCULAR AND ANTICANCER ACTIVITIES

In Asian countries, roots, barks, stems, leaves, and fruits of plants belonging to the Morinda species are considered as valuable traditional herbs. They are used in folk medicine for the treatment of many diseases, including diabetes, high blood pressure, and cancer. Anti-tubercular and cytotoxic activities of Morinda citrifolia (noni) have been reported, but Morinda coreia has not been explored ...

A. S. Avasthi, M. Bhatnagar, A. Thirumoorthy, W. Selvamurthy, N. Sinha and S. Ghosal *

Center for Plant and Environmental Biotechnology, Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(8).4062-69

4062-4069

154

77

47.

PHARMACOLOGICAL EVALUATION OF POLYHERBAL SUSPENSION AS ANTI-DEPRESSANT IN RAT

The ethanolic extract of Moringa oleifera leaves & methanolic extract of rose hips of Rosa damascena were first subjected to various phytochemical tests and further assessed for their antioxidant activity by DPPH method. Different ratio of two drugs in the polyherbal formulation were based on antioxidant activity in albino Wistar rats. Thirty rats (180 -250 g) of either sex were randomly divid...

S. Gupta and K. Mishra *

Hygia Institute of Pharmaceutical Education & Research, Lucknow, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(8).3968-74

3968-3974

151

76

43.

EVALUATION OF METHANOLIC EXTRACT OF MACROTYLOMA UNIFLORUM SEEDS ON INHIBITION OF CALCIUM OXALATE CRYSTALLIZATION- IN-VITRO

Seeds of Macrotyloma uniflorum Linn. (Fabaceae) are widely used for treatment in kidney stones in India. In This study evaluates the in-vitro effect of methanolic extract of Macrotyloma uniflorum (MEMU) on calcium oxalate crystallization. A methanolic extract of M. uniflorum seeds at different concentrations (250-1500 μg/ml) was subjected to in-vitro crystallization activity. The obtained results...

V. B. Patel and N. Acharya *

Department of Pharmacognosy, Institute of Pharmacy, Nirma University, Ahmedabad, Gujarat, India.

DOI: 10.13040/IJPSR.0975-8232.11(8).3936-43

3936-3943

151

77

54.

BIOSYNTHESIS, CHARACTERIZATION AND BIOLOGICAL STUDIES OF SILVER NANOPARTICLES USING METHANOLIC EXTRACT OF BULB OF ZEPHYRANTHES CITRINA

In the present study, an eco-friendly, cost-efficient, rapid and simple approach was applied to the synthesis of silver nanoparticles by using a methanolic extract of bulb of Zephyranthes citrina. The metal salt was reduced to ions by metabolites present in bulb extracts. The plant extracts acts both as a reducing agent as well as a capping agent. The synthesized silver nanoparticles were characte...

J. Prakash and S. Vedanayaki *

Department of Chemistry, Kandaswami Kandar’s College, Namakkal, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.11(9).4558-66

4558-4566

151

77

25.

ANTIDYSLIPIDEMIC AND ANTI-OXIDANT ACTIVITIES OF NIGELLA SATIVA SEEDS EXTRACT IN HYPERLIPIDEMIC RATS

This experimental study had approved by animal ethics of Central Drug Research Institute, Lucknow, and had undertaken to evaluate the antidyslipidemic and anti-oxidant activities of Nigella Sativa (N. Sativa), Hindi name Kalonji seeds extract in two models of hyperlipidemia. 1- triton and 2- cholesterol-rich high-fat diet (HFD) induced hyperlipidemia. N. Sativa and Gemfibrogil were macerated with ...

S. Saxena, P. T. Pandey, V. Kumar * and J. K. Saxena

Department of Biochemistry, SRMS Institute of Medical Sciences, Bareilly, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(9).4321-28

4321-4328

150

82

53.

IN-VIVO AND STABILITY STUDIES OF DRY POWDER INSUFFLATION CONTAINING TERBUTALINE SULPHATE AND ITRACONAZOLE NANOPARTICLES FOR THE TREATMENT OF ASTHMA

The present research was envisaged on the development of dry powder to treat asthma. Terbutaline sulphate (a bronchodilator) and Itraconazole (an antifungal) were used in the present study for bronchodilation and allergy to Aspergillus fumigatus (fungi) using lactose and trehalose as excipients. Dry powder insufflations were prepared by physical mixing (milling) and spray drying, out of which spra...

V. Penabaka, B. Kumar * and N. B. L. Prasad

Department of Pharmaceutics, Ratnam Institute of Pharmacy, Pidathapolur, Muthukur, SPSR Nellore, Andhra Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.11(9).4550-57

4550-4557

145

73