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ANTILITHIATIC ACTIVITY OF ETHANOLIC LEAVES EXTRACT OF DALBERGIA SISSOO LINN. ETHYLENE GLYCOL INDUCED LITHIASIS IN RATS
Aim of the Study: The aim of this study was to investigate the antilithiatic activity of ethanolic leaves extract of Dalbergia sissoo Linn. ethylene glycol induced in rats. Materials and Methods: All the chemicals were analytical grade. Cystone was obtained from from Himalaya Health Care Ltd. The ethanolic extract of plant Dalbergia sissoo Linn. leaves were given with tween 80 as vehicle administe...
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SPECTROPHOTOMETRIC DETERMINATION OF ETODOLAC USING CHARGE TRANSFER COMPLEX
In this study, we developed a cheap and precise analytic method to measure Etodolac concentration in bulk and pharmaceutical formula. The modified, updated method depends on the reaction between ferric ion and Etodolac to yield ferrous ion. Then the former ion reacted with potassium ferric cyanide to form colored compound has a maximum absorbance at 700 nm. The method was validated by calculating ...
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ANTICANCER POTENTIAL OF PLUMBAGO ZEYLANICA LINN. AND ITS ISOLATED CONSTITUENT PLUMBAGIN: A REVIEW
Varieties of natural products have been proved as a rich source of phytoconstituents which are reported for a wide range of therapeutic potential. Plumbago zeylanica L. Is one of the herbs which are traditionally used for its therapeutic value. It is reported for several bioactive chemical constituents like naphthoquinones, flavonoids, alkaloids, glycosides, steroids, tri-terpenoids, tannins, fixe...
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DEVELOPMENT OF ANALYTICAL METHOD FOR SIMULTANEOUS ESTIMATION OF AMOXICILLIN AND CARBOCISTEINE IN SOLID DOSAGE FORM BY RP-HPLC
Pharmaceutical analysis is the application of principles of analytical chemistry to drug analysis. The analytical chemistry is the science of developing accurate, precise, and sensitive methods for determining the composition of materials in terms of elements or compounds which they contain. Quality means confirming specifications and standards, and it is never an accident; it is a result of intel...
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FORMULATION AND IN-VITRO CHARACTERISATION OF VILAZODONE IMMEDIATE RELEASE TABLETS
The aim of the present study is to develop and evaluate the immediate release tablet of Vilazodone by direct compression method. The superdisintegrant crospovidone (CP), croscarmellose sodium (CCS), sodium starch glycolate (SSG), and Locust beam gum were used for the immediate release of drug from the tablet. Optimization of superdisintegrant concentration that can control the release of the drug ...
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SYNTHESIS OF NOVEL SCHIFF’S BASES AND THEIR BIOLOGICAL ACTIVITIES
A new series of Schiff's base compounds were synthesized by condensation of 1-(4-amino-4 phenyl) 3-phenyl triazene-1-ol) and substituted aldehyde and gave high yields of target compounds. Antimicrobial activity of compounds has been tested against bacterial and fungal species, namely gram-positive bacteria as S. aureus and S. pyogenes, gram-negative bacteria as E. coli and P. aeruginosa, and funga...
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GENDER WISE PREVALENCE OF COMORBIDITIES AND MEDICATION ADHERENCE AMONG TYPE 2 DIABETICS IN MALAPPURAM
Background: Type 2 diabetes is a major lifestyle disease often seen with comorbidities or complications. This study is conducted to find out the gender-wise prevalence of comorbidities and medication adherence among the diabetics in Malappuram. Methods: A cross-sectional study was conducted among the 179 diabetics selected for the study. A pre-tested interview schedule was used to collect informat...
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UTILIZATION OF MAIZE EXTRACT FOR THE SYNTHESIS AND CHARACTERIZATION OF GOLD NANOPARTICLES AT ROOM TEMPERATURE
In present work, the gold nanoparticles have been prepared through green synthesis using maize extract at room temperature, the maize extract was used as reducing and stabilizing agents for AuNPs (gold nanoparticles), synthesized gold nanoparticles were confirmed by the color change of the aqueous solution, and the PH of the solution was 7.8, after the confirmation, green gold nanoparticles were c...
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HIGH-THROUGHPUT STRUCTURE BASED VIRTUAL SCREENING TARGETING CNS FOR INHIBITED ACETYLCHOLINESTERASE REACTIVATION
Organophosphorus (OP) nerve agents blocks acetylcholinesterase and do not allow the degradation of acetylcholine. Post-treatment of organophosphate poisoning involves the treatment with oxime reactivators as an antidote, which will dephosphorylate the phosphate bond between enzyme and nerve agent. Due to CNS permeability failure of these oximes, the introduction of low molecular non-oximes has bec...
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HYPOGLYCEMIC EFFECTS OF LUFFA ACUTANGULA (L.) ROXB. FRUIT EXTRACT IN NORMAL AND STREPTOZOTOCIN-INDUCED DIABETIC RATS
Luffa acutangula (L.) Roxb. (Family: Cucurbitaceae) has been used in the folkloric Indian medicinal system to treat numerous health conditions. The fruits of the plant have been used in dysentery, jaundice, diabetes, hemorrhoids, leprosy, and ringworm infection. The present study aimed to establish the hypoglycemic effect of the aqueous fruit extracts of Luffa acutangula was investigated in normal...
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