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MEDICINALLY IMPORTANT COLEUS SPECIES, COLEUS MALABARICUS BENTH. AND MANY OTHERS OF FAMILY LAMIACEAE FROM THE WESTERN GHATS, INDIA – A REVIEW
India is renowned for its rich biodiversity and the Western Ghats, because of its varied topography and ecological conditions support a very rich flora including medicinally valuable aromatic and non-aromatic plant species. The Western Ghats are additionally documented for diversity within the ethnic communities; they have been utilizing the plant wealth for medicinal purposes and have proven succ...
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FORMULATION DEVELOPMENT AND OPTIMIZATION OF HERBAL IMMEDIATE RELEASE TABLET FOR DENGUE
Dengue is the most rapidly spreading mosquito-borne viral disease in the world. Patients with dengue fever are treated symptomatically. There is no specific allopathic treatment for dengue fever. Traditional medicinal plants have been reported to be useful in the treatment of dengue fever. The development of new anti-dengue products from bioactive compounds is necessary to find an effective treatm...
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REVIEW ON DERIVING A HYPOTHESIS FOR ACHIEVING SUPERIOR BIOAVAILABILITY OF CURCUMIN AS AN ANTITUMOR AGENT
Curcumin, chemically 1,7-bis (4-hydroxy-3-methoxyphenyl) hepta-1,6-diene-3,5-dione derived from Curcuma longa L. is an active chemical constituent used medicinally worldwide from ancient times. Though Curcumin enjoying the reputation of many pharmacological actions, it has certain setbacks with poor bioavailability. The poor water solubility is said to be the reason for poor bioavailability, rathe...
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FORMULATION AND EVALUATION OF BILAYER FLOATING TABLETS OF ATORVASTATIN AND CAPTOPRIL
The aim of the present research work was to develop a bilayer floating dosage form of immediate-release Atorvastatin (ATR) and sustained release Captopril (CPT) in matrix form for the treatment of hyperlipidaemia and hypertension to reduce multiple dosing frequencies and enhance patient compliance. ATR belongs to the BCS Class II category having poor aqueous solubility, which was enhanced by using...
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IMPACT OF CLINICAL PHARMACIST DELIVERED EDUCATION AMONG TYPE 2 DIABETES MELLITUS PATIENTS IN A TERTIARY CARE HOSPITAL
Diabetes mellitus is a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia. The aim is to study the impact of clinical pharmacists delivered education among type 2 diabetes mellitus patients in a tertiary care hospital. A prospective, interventional, randomized control study was carried out over a period of 6 months in the general medicine department of a tertiary care...
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CITRULLUS COLOCYNTHIS PHYTOSOMES: DEVELOPMENT AND PHYSIOCHEMICAL CHARACTERIZATION
Present work is aimed at development and characterization of phytosomes, novel drug delivery dosage form used to improve the bioavailability of the drug, containing ethanolic, aqueous, dichloromethane and ethyl acetate extract of Citrullus colocynthis to meet the need for better effectiveness and safety. Required phytosomal formulations were developed using different extracts of Citrullus colocynt...
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SYNTHESIS AND CHARACTERIZATION OF NOBLE ANTICANCER DRUG OF CHITOSAN-5FU CONJUGATED FORMULATION
Cancer is one of the emergings, and best-understood neoplasm’s from a genetic perspective, yet it remains the second most common cause of cancer-related death, indicating that some of its cancer cells are not removing completely by current therapies. Chitosan is a polysaccharide β-linked D-glucosamine and N-acetyl-D-glucosamine were used as conjugate to 5Fluorouracil. 5FU is one of the most com...
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A CRITICAL REVIEW ON THIRATCHAI KUDINEER -A SIDDHA DECOCTION FOR LIVER DISEASES
Pollution and overgrowing populations cause many problems such as environmental degradation, climate change, disease, etc. Among all the problems, the disease is an important factor that may affect the normal day-to-day activities of human beings, and it may be fatal sometime. Hence many researchers, government and private sectors are involved in the process of formulating new drugs to the existin...
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ANTIANXIETY AND ANTIDEPRESSANT ACTIVITY OF VALERIANA PYROLAEFOLIA
Aim of the present study was to evaluate the antianxiety and antidepressant activity of Valeriana pyrolaefolia, a member of family Valerianaceae. The antianxiety and antidepressant activities of dichloromethane extract were evaluated using the elevated plus-maze model and porsolt’s despair swim test. The studies were conducted on lacca mice, and the test materials were administered per oral rout...
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DESIGN AND DEVELOPMENT OF SUPERPOROUS HYDROGEL OF AN ANTIHYPER-TENSIVE DRUG FOR GASTRORETENTIVE DRUG DELIVERY
Superporous hydrogels (SPHs) is originally developed as a novel drug delivery system to retain drugs in the gastric medium by instant swelling on water absorption through open porous structure and maintain their integrity in that harsh environment. Atenolol, an antihypertensive drug with a short half-life, limited bioavailability, unstable nature at basic pH potentiated the need for developing a g...
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