Most Popular
FORMULATION AND EVALUATION OF MUCOADHESIVE VAGINAL TABLET FOR THE TREATMENT OF BACTERIAL VAGINOSIS
The primary purpose of this study was to formulate a mucoadhesive vaginal tablet of clindamycin phosphate. It developed to achieve an excellent therapeutic effect and patient compliance in the treatment of bacterial vaginosis. The formulation has a sustained-release effect with good mucoadhesion due to mucoadhesive polymers like Polycarbophil and Carbopol 971P NF, which decreases dose frequency. T...
1544
853
NANOEMULSION: A PROMISING AND NOVEL NANOTHERAPEUTIC VEHICLE FOR TRANSDERMAL DRUG DELIVERY
Transdermal delivery of therapeutics has been identified by scientific researchers as an alternative choice of drug administration, owing to its unique and tremendous benefit over conventional and oral administrations, but its exploration has been limited because of the “skin barricade” as its major challenge. A special formulation that is capable of meeting up and overcoming its associated ch...
1543
679
PHYTOCHEMICAL EVALUATION OF CASSIA AURICULATA USING ANALYTICAL STUDIES
Medicinal plants, herbs, spices, and herbal remedies are integral components of the alternative system of medicine since while’s ancient Cassia auriculata Linn is a potential folklore medicinal plant (Caesalpiniaceae) used for Ayurveda and Siddha systems of medicine. Plants contain a wide variety of phytochemical constituents, which are secondary metabolites and are used either directly or indir...
1543
1101
OPTIMIZATION OF PROCESS PARAMETERS FOR IMPROVED PRODUCTION OF BIO-ACTIVE METABOLITES BY ENDOPHYTIC FUNGUS CLADOSPORIUM CLADOSPORIOIDES ISOLATED FROM MANGROVE PLANT LUMNITZERA RACEMOSA LINN.
A study has been undertaken with an aim to isolate potent endophytic fungi from mangrove plant Lumnitzera racemosa Linn. Among the 10 different fungal strains isolated, one potent strain with broad-spectrum antagonistic activity was found. Basing on the morphological, cultural and molecular characteristics, the potent fungal strain was identified as Cladosporium cladosporioides. Production of bioa...
1542
628
HYDROPHILIC AND HYDROPHOBIC MATRIX SYSTEM ENGINEERED DEVELOPMENT OF EXTENDED-RELEASE TABLETS OF OXYBUTYNIN CHLORIDE
The present aim study is the formulation development and evaluation of extended-release matrix tablets of oxybutynin chloride by using hydrophilic and hydrophobic matrix systems. The pilot-scale batches of nine formulations were prepared using Eudragit RSPO, Eudragit RLPO, Carbopol 971NF, ethylcellulose individually, and in the combination of above polymer and Avicel PH102 by adopting direct compr...
1542
773
GC-MS ANALYSIS OF BIOACTIVE COMPOUNDS FROM ETHANOLIC EXTRACT OF WHOLE PLANT OF MOLLUGO OPPOSITIFOLIA L. AND THEIR PHARMACOLOGICAL ACTIVITIES
Ethanolic extract of the whole plant of Mollugo oppositifolia L. of Molluginaceae has been analyzed by using GC-MS for Bioactive compounds and for their pharmacological activities. GC-MS showed 32 compounds and is confirmed with the help of the database of NIST. Out of these, seven major Bioactive compounds are identified based on their retention time and peak area in GC-MS chromatogram. Among the...
1541
1092
SIMULTANEOUS EQUATION METHOD AND ABSORPTION CORRECTION METHOD FOR THE ESTIMATION OF PERINDOPRIL ERBUMINE AND AMLODIPINE BESYLATE IN BULK AND IN COMBINED TABLET DOSAGE FORM USING UV SPECTOPHOTOMETRY
In the present work a simple, accurate and precise method has been developed and validated for the simultaneous estimation of Perindopril Erbumine (PDE), Amlodipine Besylate (AMD)and in their combined dosage form by UV Spectrophotometric Methods. The Method A employs estimation of drugs by simultaneous equation method (SEM) using 298.3 nm and 231.9nm i.e. λmax values of PDE and AMD respectively. ...
1539
670
0
COMPOUNDS FROM TROPIDIA CURCULIOIDES AS INDUCERS OF APOPTOSIS IN CANCER CELLS
Arunachal Pradesh (AP), the North-eastern state of India, is a natural habitat of 550 species of orchids including 37 species of medicinal importance. Though these plants are used extensively by locals for various ailments, very few scientific investigations have been conducted to establish their pharmacological potential. In the present study, we selected Tropidia curculioides, a relatively unexp...
1537
658
IMPACT OF CLINICAL PHARMACIST DELIVERED EDUCATION AMONG TYPE 2 DIABETES MELLITUS PATIENTS IN A TERTIARY CARE HOSPITAL
Diabetes mellitus is a metabolic disorder of multiple etiologies characterized by chronic hyperglycemia. The aim is to study the impact of clinical pharmacists delivered education among type 2 diabetes mellitus patients in a tertiary care hospital. A prospective, interventional, randomized control study was carried out over a period of 6 months in the general medicine department of a tertiary care...
1535
812
AN UPDATED REVIEW ON THE THERAPEUTIC POTENTIAL OF PRUNUS ARMENIACA
Excessive drug therapy, environmental pollutants, hepatic cancer and alcoholic intoxicants are the main causes of liver disorders. The hepatic disorders/toxicity can occur by several mechanisms like cytochrome P450 activation, lipid peroxidation, induction of nitric acid synthase, mitochondrial dysfunction, activation of pro-inflammatory mediators and bile acid-indu...
1535
1081