Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
FORMULATION AND EVALUATION OF TRANSDERMAL DRUG DELIVERY OF RALOXIFENE HYDROCHLORIDE
The present investigation was taken up to prepare and evaluate a transdermal drug delivery system (patch) of Raloxifene Hydrochloride to increase its bioavailability. The matrix type patches were prepared using different ratios of Eudragit RL100, Poly vinyl Pyrrolidone K-30, HPMC, CAP and PEG6000 in different ratios. All the prepared formulations were subjected to physical studies (weight variatio...
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STUDIES ON ANTIDIARRHOEAL ACTIVITY OF LEAVES OF AMORPHOPHALLUS PAEONIIFOLIUS IN EXPERIMENTAL ANIMALS
Acute diarrhoea is one of the principal causes of death in the infants, particularly in developing countries. An array of medicinal plants with anti-diarrhoeal properties has been widely used by the traditional practitioners; however, the efficacy of many of these anti-diarrhoeal conventional medicines has not been scientifically evaluated. Hence the present study was under taken to explore anti-d...
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ROUTINE BLEEDING TECHNIQUES IN LABORATORY RODENTS
Collecting blood from Lab animals is necessary for a wide variety of scientific studies, and there are a number of efficient methods available. It is important to remember that blood collection can stress the animals, and may have an impact on the outcome of research data. Potential adverse affects viz. Hypovolemic shock, anemia, stress, haemorrhage, bruising, thrombosis; infection at the site of...
9461
1931
IN VIVO AND IN VITRO ANTIOXIDANT ACTIVITIES OF COUMARIN ON CHEMICAL INDUCED HYPERGLYCEMIC RATS
The present study was aimed at investigating the antioxidant activities of coumarin in streptozotocin (STZ)-nicotinamide (NA) induced type 2 diabetic rats. Diabetes was induced in experimental rats by a single intraperitoneal (i.p.) injection of STZ (45 mg/kg body weight (b.w.)), 15 min after the i.p. administration of NA (110 mg/kg b.w.). Diabetic rats were administered coumarin intragastrically ...
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DENDRIMERS: NOVEL DRUG NANOCARRIERS
Dendrimers are unique class of the polymer which is characterized by its extensively branched 3D structure that provides a high degree of surface functionality and versatility. Many drugs used in various therapies are facing difficulties like toxicity or nonspecific targeting. New delivery technologies could help to overcome this challenge. Nanostructures with uniform and well-defined particle siz...
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EVALUATION OF ANXIOLYTIC ACTIVITY OF HYDROALCOHOLIC ACTIVITY OF TEPHROSIA PURPURIA (L) PERS ON SWISS ALBINO MICE
The present work is to evaluate the anxiolytic activity of a hydroalcoholic extract of Tephrosia purpuria (L) Pers (HAETP) in mice using the elevated plus-maze (EPM), elevated zero-maze (EZM), Y-maze and hole-board models. Furthermore, the anxiolytic effects of HAETP were compared to a known active anxiolytic drug diazepam. The extract, administered orally, in two different doses of HAETP 200 mg/k...
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EVALUTION OF ANTI-DIABETIC ACTIVITY OF METHANOL EXTRACT OF DIGERA MURICATA (L) MART IN ALLOXAN INDUCED DIABETIC RATS
Digera muricata (L.) Mart (Amaranthaceae) commonly known as Cancali soppu widely used in traditional system of medicine for the treatment of diabetes mellitus In the present study, Methanol extract of Digera muricata(MEDM) leaves were subjected to phytochemical investigation and evaluated for antidiabetic activity in alloxan induced diabetic rats. MEDM (100, 200 mg/kg) and Glibenclamide (3mg/k...
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DEVELOPMENT OF A NOVEL FORMULATION FOR TRANSDERMAL DELIVERY OF AN ANTIDEPRESSANT DRUG
The aim of this study was to investigate the effect of permeation of drug into skin by taking three different vesicle size niosomal formulations. The combined influence of 3 independent variables in the preparation of venlafaxine niosomes by the Ether Injection Method and it was to derive a second order polynomial equation and construct contour plots to predict responses. Seventeen batches were pr...
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SOLID DISPERSION – A PROMISING NOVEL APPROACH FOR IMPROVING THE SOLUBILITY OF POORLY SOLUBLE DRUGS
Solid dispersions is an efficient means of improving the dissolution rate and hence the bioavailability of a range of poorly soluble drugs. This article reviews the various types of solid dispersion, preparation techniques for solid dispersion and compiles some of the recent technologies. Some of the practical aspects to be considered for the preparation of solid dispersions, such as selection of ...
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PHARMACOLOGICAL REVIEW OF AEGLE MARMELOS CORR. FRUITS
Aegle marmelos Corr. (Rutaceae), commonly known as Bael, Bengal Quince is a tree of Indian origin, well known from pre- historic time. Utilization of bael fruit in day-to-day life has a great nutritional, environmental as well as commercial importance. All the parts of this tree including stem, bark, root, leaves, fruit and seeds at all stages of maturity has medicinal virtues and has been used in...
8886
1913