Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
EFFECT OF DIFFERENT CARBON AND NITROGEN SOURCES ON α- AMYLASE PRODUCTION FROM BACILLUS AMYLOLIQUEFACIENS
Amylases are among the most important enzymes in present-day biotechnology. The effects of various carbon and nitrogen sources on α-amylase production by submerged fermentation (smF) from Bacillus amyloliquefaciens was investigated. The study revealed that the levels of the α- amylase production varied greatly with the type and concentration of carbon and nitrogen sources used. The highest α-am...
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ANTI-DIABETIC ACTIVITY OF ROOTS OF QUERCUS INFECTORIA OLIVIER IN ALLOXAN INDUCED DIABETIC RATS
The methanolic extract of roots of Quercus infectoria Olivier at a dose of 250 mg/kg and 500 mg/kg body weight respectively was tested for anti-diabetic activity in Alloxan-induced hyperglycaemic rats. The blood glucose levels were measured at 0, 2h, 4h and 6h after the treatment. The methanolic extract reduced the blood glucose Alloxan- induced diabetic rats from 285.52 to 206.57mg/dl, 6h after o...
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DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR SIMULTANEOUS ESTIMATION OF METOPROLOL SUCCINATE AND TELMISARTAN IN COMBINED PHARMACEUTICAL FORMULATION
Four simple, rapid, precise, economical and accurate spectrophotometric methods have been developed for simultaneous analysis of Metoprolol succinate and Telmisartan in their combined dosage form. Method 1, First derivative simultaneous equation method (Vierodt’s method). It employs formation and solving of simultaneous equation using two wavelengths 230.2 nm (λmax of Metoprolol succinate) and ...
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IN VITRO EVALUATION OF ANTIBACTERIAL POTENTIAL OF ANNONA SQUAMOSA L. AGAINST PATHOGENIC BACTERIA
Three different solvent extracts of seeds of Annona squamosa L. were studied for its antibacterial activity. Agar cup method was selected to test antibacterial activity using two Gram-positive (Bacillus subtilis, Staphylococcus aureus) and three Gram-negative (Escherichia coli, Pseudomonas aeruginosa and Klebsiella pneumoniae) bacteria. The screeningresults showed that highest inhibition was obser...
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FORMULATION AND EVALUATION OF CONTROLLED POROSITY OSMOTIC DRUG DELIVERY SYSTEM OF METOPROLOL SUCCINATE
Controlled porosity osmotic tablet of metoprolol succinate prepared and evaluated in this study. Metoprolol succinate is very high soluble drug, so complete drug release obtained very fast. It is difficult to formulate osmotic tablet of Metoprolol succinate which gives drug release up to 24 hr at zero order. To get desired dissolution profile various formulation parameters like osmogen concentrati...
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ANALGESIC, PHYTOCHEMICAL AND ACUTE TOXICITY EVALUATION OF THE METHANOL EXTRACT OF THE LEAVES OF PTEROCARPUS SANTALINOIDES- FAMILY FABACEA
Pterocarpus santalinoides, family- Fabaceae was claimed to have analgesic properties. The people of Ogidi in Idemili North Local Government Area of Anambra State, Nigeria used it in the management of aches and pains. This study is therefore aimed at determining this claim of the activities of Pterocarpus santalinoides using the leaves which will serve as a criterion to recommend the ethno pharmaco...
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ANTIBACTERIAL ACTIVITY OF SOME SELECTED INDIAN MEDICINAL PLANTS
There is a continuous and urgent need to discover new antimicrobial compounds with diverse chemical structures and novel mechanisms of action because there has been an alarming increase in the incidence of new and re-emerging infectious diseases. In recent years, drug resistance to human pathogenic bacteria has been commonly reported from all over the world. In the present scenario of emergence of...
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PHYTOCHEMICAL AND BIOLOGICAL EVALUATION OF VITEX NEGUNDO LINN: A REVIEW
Vitex negundo Linn. belong to family Verbenaceae. It is an important medicinal plant.Literaturesurvey of V. negundo revealed the presence of different classes of natural products including essential oil,triterpenes, diterpenes, sesquiterpenes, lignan, flavonoids,flavones glycosides, iridoid glycosides, and stilbene derivative. The plant is traditionally reported for its use for the treatment of ...
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A NOVEL APPROACH IN GASTRO RETENTIVE DRUG DELIVERY SYSTEM: FLOATING DRUG DELIVERY SYSTEM
The task of achieving efficient delivery of drugs that have poor bioavailability or narrow absorption windows have plagued the pharmaceutically industry for decades. Thus, much research has been dedicated to the development of novel polymeric-based gastro retentive drug delivery technologies that may optimize the bioavailability and subsequent therapeutic efficacy of such drugs. Several technical ...
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PHYTOCHEMICAL AND PHARMACOLOGICAL SCREENING OF SPHAERANTHUS INDICUS LINN. FOR ANTIMICROBIAL ACTIVITY
Sphaeranthus indicus Linn (Asteraceae) is a common annual spreading herb found in rice field throughout India. Six crude extracts were prepared from the whole plant Sphaeranthus indicus using different solvents by cold maceration process. The extracts were subjected to screening to detect potential antimicrobial activity against S. aureus, B. substillus, P. Gentamycin and Nystatin as standard by c...
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