Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
IN-VITRO BIOACTIVE POTENTIAL OF ENDOPHYTIC FUNGI CURVULARIA LUNATA ISOLATED FROM MEDICINAL PLANT FICUS RELIGIOSA
Several studies undertaken in the recent past have demonstrated that endophytic fungi are capable of producing a number of important bioactive secondary metabolites, hitherto known only from plants, thereby raising the potential of using endophytes as alternative sources for these metabolites. Occasionally, the compounds produced by endophytic fungi are similar to those produced by the respective ...
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1057
TECHNOLOGICAL DEVELOPMENT IN COMPARISON WITH IDEAL FORMULATION OF BCS CLASS IV DRUG – RIFAXIMIN
The solubility, dissolution, and gastrointestinal permeability are the prime factors for drug absorption. Rifaximin is a structural analogue of rifamycin that inhibits RNA synthesis by binding to β-subunit of bacterial DNA-dependent RNA polymerase. Rifaximin is a class 1V drug having low solubility and low permeability. My theme of the design is to develop the technological characterization of do...
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ALPHA-AMYLASE INHIBITORY ACTIVITY OF KATANKATERYADI KWATHA (K. KWATHA) IN MANAGEMENT OF TYPE 2 DIABETES
Objectives: The objective of the study is to find out the alpha-amylase inhibitory activity of Katankateryadi Kwatha. The alpha-amylase enzyme is the key source for postprandial hyperglycaemia, which is responsible for Type 2 Diabetes. Methodology: The crude drugs of Katankateryadi Kwatha (K. Kwatha) were collected from a local market. The Kwatha was prepared and dried with rotatory evaporator, un...
2363
1007
A NOVEL APPROACH TOWARDS GREEN SYNTHESIS OF ZINC NANOPARTICLES FROM BANIUM PERSICUM AND ITS PHARMACOLOGICAL EFFICACY
Integration of nano-science in medicine leads to the development of biomedical products that help society in a faster and safer manner. In the present studies, Zinc nanoparticles were synthesized by green synthesis route using aqueous extracts of Banium persicum, and characterization was done through UV, SEM, TEM, FT-IR, and XRD. The synthesized nanoparticle was spherical in shape with an average ...
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EVALUATION OF ANTIDIABETIC ACTIVITY OF ECHINOCHLOA COLONA PLANT EXTRACT
The current work comprises the assessment of antidiabetic activity of chloroform, ethyl acetate, and ethanol fractions and isolation of some phytoconstituents from chloroform fraction obtained from ethanolic extract of Echinochloa colona. The antidiabetic activity was performed using streptozocin induced diabetic model in male Wistar rats (150-200 g). The best restraint results were for metformin,...
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IDENTIFICATION AND OPTIMIZATION OF BINDING SITE FOR AN ACTIVE METABOLITE OF CLOPIDOGREL, PRASUGREL AND TICLOPIDINE ON RECEPTOR P2Y12
In this article, an attempt was made to develop molecular docking studies on active metabolites of Prasugrel, Clopidogrel, and Ticlopidine acting as protein P2Y12 inhibitors. Molecular docking analysis was performing by using autodock version 4.3 adjoin with discovery studio to better understand the interactions between P2Y12 targets and inhibitors in this series. Hydrophobic and hydrogen bond int...
2067
1362
EVALUATION OF TOTAL POLYPHENOLIC CONTENT AND FREE RADICAL SCAVENGING ACTIVITY OF ETHANOLIC AND AQUEOUS EXTRACTS OF CORDIA OBLIQUA FRUITS
The present study was carried out to investigate the phytochemicals, Total polyphenolic content and In-vitro antioxidant activity of ethanolic and aqueous extracts of Cordia obliqua fruits. Objective: To determine the primary and secondary metabolites present in different extracts, to aces the quantity of phenolic compounds by total phenolic content and to evaluate the % inhibition of free radical...
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946
INHIBPRED: A WEB SERVER FOR PREDICTING INHIBITORY ACTIVITY OF MOLECULES AGAINST HUMAN HDAC6 PROTEIN
Oral squamous cell carcinoma (OSCC) is the most commonly occurring malignancy of the oral cavity. Over the years, the incidence and morbidity rate of Oral Cancer patients has increased worldwide. In the last few decades, although oral cancer treatment modalities have advanced, the survival rate of oral cancer patients is very low. Thus, there arises a need for the identification of new drug target...
1656
979
EVALUATION OF HUMAN SALIVARY METALLOPROTEINASE INHIBITORS IN PLANT LEAVES
Previous studies investigated the host-derived salivary matrix metalloproteinases (MMPs) are responsible for dentin caries progression. The utilization of the MMP inhibitors can become a successful strategy to control dentin caries. In this study, we have tested twenty-four different medicinal plant leaf extracts against human salivary MMPs for investigation of inhibitors. Total phenolics were ext...
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FORMULATION AND EVALUATION OF DICLOFENAC SODIUM MICROEMULSION SUBCUTANEOUS DRUG DELIVERY SYSTEM
The objective of this current work is to develop the formulation and evaluation of a subcutaneous drug delivery system based on diclofenac sodium microemulsion. A different formulation has been formulated using a modifying amount of gelling agent and a penetration enhancer. Pseudo ternary phase diagrams were constructed for different microemulsion formulations composed of the formulations FEG1, FE...
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