Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF SOFOSBUVIR AND VELPATASVIR BY UV-VISIBLE SPECTROPHOTOMETRY
A simple, linear, precise, and economical UV spectro-photometric method has been developed for the simultaneous estimation of sofosbuvir and velpatasvir in the bulk and pharmaceutical dosage form. The standard stock solutions were prepared by using methanol as solvent. Estimation of sofosbuvir and velpatasvir was conducted by using a simultaneous equation method based on the measurement of Maximum...
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DESIGN AND EVALUATION OF ZERO-ORDER DRUG-RELEASING RIVASTIGMINE TRANSDERMAL SYSTEM
Rivastigmine is used for the treatment of mild to moderate dementia of the Alzheimer’s type. Transdermal delivery of Rivastigmine is preferable to improve gastrointestinal tolerability. A novel transdermal system with zero-order release kinetics was developed following a hybrid technique in a combination of the micro reservoir and adhesive dispersion system. The transdermal system was prepared b...
1938
1218
COLD-ACTIVE EXO-INULINASE ENZYME: ISOLATION AND SCREENING OF ENDOPHYTIC MICROBES FROM FRUITS
Microbial inulinases have a great potential for industrial use in the production of fructose from inulin. Optimization of the growth parameters of the microbes is essential to obtain inulinase in sufficient quantity. The present work aims to obtain inulinase from different fruits of endophytic bacteria and optimize its growth parameters. In a total of 22 isolates and among them, each one isolates ...
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ANTI-EPILEPTIC ACTIVITY OF INDIAN MEDICINAL PLANTS – A REVIEW
In global debates, traditional herbal medicines are getting a lot of attention, especially in the treatment of Epilepsy. This deadly disease is estimated to affect around 50 million people around the world. This neurological disorder is believed to be due to excessive electric discharge in the brain and the release of neurotransmitter substances. Antiepileptic drugs are useful but are expensive an...
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SCREENING OF MEDICINAL PLANTS USED FOR PREVENTION AND TREATMENT NEURODEGENERATIVE DISEASES: A REVIEW
Amyotrophic lateral sclerosis (ALS), Parkinson's disease, Alzheimer's disease, and Huntington's disease occur as a result of the neurodegeneration process. No specific treatment was found to reduce or stop neurodegenerative diseases. In conventional medicine, many plants have been used to treat neurodegenerative diseases. Natural products play an important role in the prevention and treatment of v...
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COMPARATIVE REVIEW OF MOMORDICA CHARANTIA AND MOMORDICA DIOICA: AN UPDATE
Momordica charantia and Momordica dioica species belong to the Cucurbitaceae family. Momordica charantia and Momordica dioica climbing creeper plants are used both in the prevention and cure of various diseases and in the food of humans. Momordica charantia is also known as bitter gourds, bitter melon, karela, and balsam pear. Momordica charantia contain phytochemical constituents such as alkaloid...
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THE ANTICANCER ACTIVITY OF BIOACTIVE COMPOUNDS FROM MEDICINAL PLANTS: AN REVIEW
Cancer is a serious health concern in both developed and developing nations. Cancer causes due to unwanted growth of cells and irregular cell division. Medicinal plants have been used by village folk from ancient times. The plants contain various bioactive compounds that can be used for treating cancer. Some of the phyto compounds isolated from plants have shown promising results; these include ...
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ANDROGRAPHOLIDE AND HESPERIDIN – A BRIEF OVERVIEW
Andrographolide is a labdane diterpenoid isolated from the leaves and roots of Andrographis paniculata Nees (Acanthaceae). Andrographolide is isolated by various processes and the simple method is the maceration process. It is bitter in taste and used as hepatoprotective, cholinergic, antispasmodic, stomachic, anthelmentic, alterative, blood purifier, and febrifuge. It promotes the secretion of bi...
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PHARMACOLOGICAL STUDIES OF MEDICINAL PLANT CITRULLUS COLOCYNTHIS: A REVIEW
The medicinal plant Citrullus colocynthis is very significant for indigenous medicine. The pharmacological effects of root, fruits, seeds, leaves, and the whole C. colocynthis have been practices for the treatment of diseases. Phytochemical screening of the fruits of C. colocynthis has observed several bioactive compounds. The glycosides, flavonoids, alkaloids, carbohydrates, fatty acids, and esse...
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CYTOTOXIC AND ANTIPROLIFERATIVE STUDIES OF ISOCORDOIN AND SOME DERIVATIVES AGAINST PROSTATE CANCER CELL LINES
The proposed study was to evaluate the in-vitro cytotoxic and antiproliferative activities on prostate cancer cell lines of isocordoin (1) and 2’,4’-dihydroxy-3’-(g,g-dimethylallyl) dihydrochalcone (2), chalcones isolated from roots of Lonchocarpus xuul Lundel, together with four analogues of 1. Isolation of compounds 1 and 2 from L. xuul roots and chemical modification were in accordance wi...
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