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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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19.

SYNTHESIS, CHARACTERIZATION, MOLECULAR DOCKING STUDIES AND ANTHELMINTIC AND ANTI-CANCER ACTIVITY OF PYRAZOLE CONTAIN NOVEL INDOLIN-2-ONE DERIVATIVES

Background: Imidazole-5-one scaffold has been predicted in the important synthetic drug analogs, which gave valuable information for treatment and high binding affinity to the multiple receptors helpful drug development. Objective: To synthesize and evaluate the anthelmintic, anticancer, and Insilco docking studies of pyrazole contain novel Indole derivatives (4a-4h). Methods: In the present work,...

Hemalatha Sattu *, Sayeda Hinanaaz and Oleti Navneetha

Department of Pharmaceutical Chemistry, S. N. Vanita Pharmacy Mahavidyalaya, Tarnaka, Secunderabad, Hyderabad, India.

DOI: 10.13040/IJPSR.0975-8232.14(7).3404-13

3404-3413

634

323

21.

ISOLATION, CHARACTERIZATION AND EVALUATION OF ANTI-ULCER ACTIVITY OF PHYTOCONSTITUENTS PRESENT IN MORINGA OLEIFERA LEAF

Moringa oleifera leaf is widely used in the traditional medicine system and also used as a food by different communities and local tribes of Assam in India. Moringa oleifera leaf contains various bioactive compounds such as alkaloids, flavonoids, rutin, steroids, etc. The flavonoids quercetin act as an anti-ulcer agent, and rutin have a gastro cytoprotective effect i.e., present in M. oleifera lea...

Banik Bapan *, Mallik Ajanta, Barman Priyanka and K. Das Malay

Department of Pharmaceutical Sciences, Dibrugarh University, Dibrugarh, Assam, India.

DOI: 10.13040/IJPSR.0975-8232.13(3).1218-24

1218-1224

633

316

5.

PHARMACEUTICAL APPLICATIONS OF LYOPHILIZATION: RECENT UPDATES AND ADVANCEMENTS

For almost five decades, from its application in preserving blood plasma to stabilizing pharmaceuticals and biopharmaceuticals, lyophilization has been used in life sciences. Lyophilization is a popular drying technique for preserving various drugs, formulations and biological materials such as proteins, plasma, and living cells. The researchers have made significant efforts to develop lyophilize...

M. S. Motwani, A. R. Shahu, M. J. Umekar, D. M. Biyani and K. J. Wadher *

Department of Pharmaceutics, Smt. Kishoritai Bhoyar College of Pharmacy, Kamptee, Nagpur, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.14(4).1594-03

1594-1603

633

454

44.

FORMULATION AND EVALUATION OF TOPICAL ITRACONAZOLE NANOGEL

Itraconazole is a triazole antifungal category drug used for the treatment of local &Systemic fungal infections. Itraconazole is not recommended to neutropenic and other immune-compromised patients who have difficulty swallowing the oral capsule formulation, and it has many side effects. Commercially, Itraconazole topical gel preparation is not available in the market; thus, this formulation i...

Ashwini P. Potulwar * and Shraddha S. Tiwari

School of Pharmacy, SRTM University, Vishnupuri, Nanded, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.14(4).1954-61

1954-1961

632

428

5.

CURRENT REGULATORY REQUIREMENTS FOR MEDICAL DEVICES IN US, EU, AND INDIA

Clinical results of various medical treatments using medical devices demonstrate continuous advances, dealing with multiple types of products covering a vast range of applications in the last two decades. Millions of people rely on medical devices to diagnose and manage illnesses. A typical framework for medical device regulations is a whole product life cycle regulatory system that covers product...

N. Suganthi, Kaviya Suresh and B. Anbarasan *

Department of Pharmaceutics, Sri Ramachandra Faculty of Pharmacy, SRIHER (DU), Porur, Chennai, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.14(10).4733-40

4733-4740

630

392

4.

HETEROCYCLIC COMPOUNDS WITH THEIR RECENT DEVELOPMENT: AN INTEGRATED APPROACH

Organic chemist has developed the number of heterocyclic compounds. The heterocyclic compounds have gained more attention in medicinal and organic chemistry because of their numerous biological activities. There are various types of the heterocyclic compound available for several biological activities such as antibacterial activity, anticancer activity, antiepileptic activity, antipsychotic activi...

P. L. Ladda, S. S. Thorat *, N. N. Khebude and S. B. Powar

Shree Tarun Mandal, Kolhapur, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.15(3).642-655

642-655

630

274

9.

ETHICAL LANDSCAPE OF HERBAL MEDICINES

Remarkable numbers of people have a false belief in naturally obtained herbal medicines as they are safe to use, omitting the fact that herbal medicines have pharmacological action like allopathic medicines. Many plants are poisonous and there is less safety data available for herbal medicines. Adverse drug reactions associated with herbal medicines are overdose and toxicity, herb interactions and...

M. S. Umashankar *, A. Rakesh Rosario, S. Pavithra and S. Lavanya

Department of Pharmacy, SRM College of Pharmacy, Faculty of Medical and Health Science, SRM Institute of Science and Technology, S. R. M. Nagar, Kattankulathur, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.13(8).3056-61

3056-3061

629

274

3.

UNDERSTANDING OF PHYTO-NANOMEDICINE FOR THE MANAGEMENT OF INFLAMMATION AND WOUND HEALING: AN OUTLOOK

Nanoparticles are the modern-day drug delivery system for biocompatible drugs. Numerous products have developed from nanotechnology to develop effective wound healing and inflammatory treatments. Plant extracts (phytoconstituents) have a lot of therapeutically potential because of their distinctive properties, including anti-inflammatory, antioxidant and insulin-sensitizing properties etc. Furthe...

Deepika Aggarwal, Kamal *, Manjusha Choudhary, Gaurav Agarwal, Ashish Kumar and Diksha Sharma

Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, Haryana, India.

DOI: 10.13040/IJPSR.0975-8232.14(10).4713-23

4713-4723

629

420

17.

DESIGN, DEVELOPMENT AND FORMULATION OF ECONAZOLE NITRATE CO-CRYSTAL LOADED GEL TO CURE TOPICAL ANTIFUNGAL DISEASE

In the past years many drug discoveries were investigated to be poorly soluble in aqueous medium. These poorly aqueous soluble drugs include Econazole Nitrate (ECZN) having high permeability. ECZN is an effective, potent anti-fungal drug used to cure large range of fungus. Oral administration of ECZN causes gastrointestinal irritation. To overcome or avoid the “first pass metabolism” and to op...

Mohammad Wais, Priyanka S. Gala * and Anagha Raut

Department of Pharmaceutics, H. K. College of Pharmacy, Oshiwara, Jogeshwari [W], Mumbai, Maharashtra, India.

DOI: 10.13040/IJPSR.0975-8232.14(11).5253-68

5253-5268

629

499

44.

IN-VITRO AND IN-VIVO ANTIOXIDANT PROPERTIES OF STEM EXTRACTS OF CROTON MEMBRANACEUS

Croton membranaceus is a tropical plant that grows wildly in some West African countries. Though several parts of this plant are used for the treatment of diverse disease conditions, its root extracts are traditionally used mainly in Ghana for the management of prostate diseases. This present study aimed to investigate the in-vitro and in-vivo antioxidant activities of the stem extracts of C. memb...

D. K. Afriyie *, E. Ofori-Ameyaw, D. O. Acheampong, I. Tuffour and Regina Appiah-Opong

Department of Biomedical Sciences, University of Cape Coast, Ghana, College of Health Sciences, University of Ghana.

DOI: 10.13040/IJPSR.0975-8232.13(2).921-29

921-929

629

324