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ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES OF LEAF EXTRACTS OF BERBERIS ARISTATA AND ABIES WEBBIANA: THE ETHNOMEDICINAL PLANTS
This study was carried out to investigate the antibacterial and antifungal potentials of Abies webbiana and Berberis aristate Linn. The study aims to assess the antimicrobial activity and determine the zone of inhibition of extracts on some bacterial and fungal strains. The extracts determined the antimicrobial activity using the agar disc diffusion method. The antibacterial and antifungal activit...
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FORMULATION, EVALUATION AND COMPARISON OF NATURAL AND SYNTHETIC SUPERDISINTEGRANTS USED IN THE FAST-DISSOLVING TABLET BY DIRECT COMPRESSION TECHNIQUES
Fast-dissolving tablets are a novel drug delivery system that provides the fastest onset of action and rapid pharmacological effects after administration. It can be administered simply by putting the tablets on the tongue, without the need for water. Mostly, this drug delivery system is efficient in emergency situations where an immediate drug response is needed. For the formulation of this kind o...
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LISINOPRIL PROTECTS THE LIVER AGAINST FUNCTIONAL DISORDERS AND HISTOLOGICAL DAMAGES INDUCED BY FERROUS SULFATE IN RATS
Iron overload has toxic effects on the body. Hepatotoxicity is a common finding in iron-overloaded patients, resulting from iron deposition in hepatocytes. Angiotensinɪɪ is involved in developing hepatic damage through its pro-oxidative properties. Therefore, the current study aimed to investigate the therapeutic effect of the ACE inhibitor, lisinopril, against ferrous sulfate-induced hepatic fu...
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REVIEW ON NARINGIN: METHOD OF ISOLATION, ANALYTICAL DEVELOPMENT, AND ITS RECENT PHARMACOLOGICAL ACTIVITIES
Naringin is a flavonoid isolated from different citrus fruits like Grapefruit, Orange, Pomelo, Lemon, etc, which are commonly called local fruit. Naringin is found in the white spongy portion of citrus peel. Its content varies from 0.65 mg/gm in the mandarin peel to 14.40mg/gm in the grapefruit peel. Naringin is metabolized to the flavanone naringenin by the enzyme Naringinase present in the liver...
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UV-B RADIATION INDUCED DIFFERENTIAL PHYSIOLOGICAL AND BIOCHEMICAL RESPONSES IN NOSTOC COMMUNE AND ANABAENA VARIABILIS
Batch cultures of two cyanobacterial species i.e., Nostoc commune and Anabaena variabilis were used to evaluate the impact of UV-B radiation on growth, photosynthetic pigments, lipid peroxidation, proline content, protein content as well as on the enzymes nitrate reductase and glutamine synthetase. The essential targets of UV-B radiation are the photosynthetic apparatus, photosynthetic pigments, a...
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MOMORDICA CHARANTIA (BITTER MELON) CHEWABLE LOZENGES- A HYPOTHESIS-BASED APPROACH TO THE TREATMENT OF DIABETES MELLITUS
Diabetes Mellitus is a prevalent global health problem commonly known as diabetes, a metabolic disease resulting in high blood sugar levels. India considered as "Capital of Diabetes” and more than 61 million Indians suffer from diabetes. Plants are incredible natural reservoirs of phytochemicals and vital medicines. Momordica charantia (MC), commonly known as bitter melon, has high phytochemical...
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PREPARATION AND STANDARDISATION OF PANCHA HARITHAKADI CHURNA BY HPTLC
Standardization of herbal formulation is essential to assess the quality of drugs for its therapeutic efficacy. Pancha Haritha kadi Churna (PHC) is a traditional poly herbal formulation meant for digestion which consists of five ingredients having digestive property. It is used for the treatment of Constipation and Bloating. Churna’s will play an important role in gastro intestinal problems and ...
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FORMULATION AND EVALUATION OF SATRANIDAZOLE BY SELF EMULSIFYING DRUG DELIVERY SYSTEM
Background: Satranidazole is a class II drug per biopharmaceutical classification systems with poor aqueous solubility and antiprotozoal and anti-bacterial properties. Aim: Therefore, the purpose of the present study was to enhance the solubility of Satranidazole using a self-emulsified drug delivery system (SEDDS). Methods: SEDDS was prepared using Satranidazole (10 mg) and dissolved in the oil p...
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CLINICAL STUDY ON THE IMMUNOMODULATORY EFFECT OF NIDIGDHIKADILEHA ON PRANAVAHA SROTO DUSHTI W. S. R. UPPER RESPIRATORY TRACT INFECTIONS IN CHILDREN
Aim of study: A Randomized controlled trial was planned to evaluate the Clinical efficacy of Nidigdhikadileha an Ayurveda multi-dimensional herb preparation in children suffering from Recurrent Respiratory tract infection in children. Nidigdhikadileha contains Nidigdhika (Solanum Xanthocarpum), Pippali (Piper longum), Amrita (Tinospora cardifolia), and Nagar (Zingiber officinale). All these drugs ...
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ATTENUATION OF INFLAMMATION BY ETHANOLIC EXTRACT OF CAESALPINIA BONDUCELLA USING IN-VITRO INFLAMMATORY MODELS
Background: Caesalpinia bonducella F. (Leguminosae) has long been used in traditional medicinal treating methods. It has high therapeutic values in India Ayurveda. They contain tannin, saponins, flavonoids, and alkaloids. The seeds of Caesalpinia bonducella are claimed to be styptic, purgative, anthelmintic and cures inflammations. Today the interest in traditional medicine and demand for more pla...
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